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Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. Additionally we are shipping Streptolysin O Antibodies (5) and and many more products for this protein.
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Streptococcus pyogenes (Streptococcus hemolyticus) SLO Protein expressed in Escherichia coli (E. coli) - ABIN2452205
Maeda, Ide, Koike, Uchiyama, Kinoshita: GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus. in Nature cell biology 2008
Show all 3 Pubmed References
Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
, Streptolysin O
, Thiol-activated cytolysin