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Structural Maintenance of Chromosomes 2 Proteins (SMC2)

Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010].. Additionally we are shipping SMC2 Antibodies (46) and SMC2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMC2 10592 O95347
SMC2 14211 Q8CG48
Rat SMC2 SMC2 362519  
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Top SMC2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SMC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Structural Maintenance of Chromosomes 2 (SMC2) Interaction Partners

Human Structural Maintenance of Chromosomes 2 (SMC2) interaction partners

  1. SMC2 (or the condensin complex (show SMC4 Proteins)) is a novel molecular target for the treatment of MYCN (show MYCN Proteins)-amplified neuroblastoma (show ARHGEF16 Proteins).

  2. analysis of functional differences of SMC2 and SMC4 hinge domain between condensins and cohesin in DNA recognition

  3. SMC2 gene is altered by both frameshift mutation and loss of expression in gastric and colorectal cancers, suggesting that SMC2 gene alterations might be involved in pathogenesis of these cancers

  4. WNT (show WNT2 Proteins) signaling can directly activate SMC2 transcription as a key player in the mitotic cell division machinery.

  5. Studies indicate that tagged SMC2 subunit of the condensin complex (show SMC4 Proteins) with the streptavidin-Binding Peptide (show HP Proteins) optimising efficacious use of this tag for protein analysis.

  6. human SMC2 hinge domain with short coiled coils was cloned, expressed, purified and crystallized in the orthorhombic space group C222 in native and SeMet-derivatized forms

  7. mutation analysis of hCAP-C (show SMC4 Proteins) & hCAP-E in leukemia-lymphoma cell lines including 8 pyothorax-associated lymphoma (PAL); 3 of 8 PAL cell lines have hCAP-C (show SMC4 Proteins) or hCAP-E heterozygous mutations, indicating condensin mutations are relatively frequent in PAL

SMC2 Protein Profile

Protein Summary

Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.

Gene names and symbols associated with SMC2

  • structural maintenance of chromosomes 2 (SMC2)
  • structural maintenance of chromosomes 2 (Smc2)
  • structural maintenance of chromosomes 2 (smc2)
  • 5730502P04Rik protein
  • AI255214 protein
  • AW545314 protein
  • CAP-E protein
  • CAPE protein
  • fb92e05 protein
  • Fin16 protein
  • SCII protein
  • SMC-2 protein
  • Smc2l1 protein
  • wu:fb92e05 protein
  • xcap-e protein
  • zeh1628 protein
  • zgc:55326 protein

Protein level used designations for SMC2

SMC protein 2 , SMC2 (structural maintenance of chromosomes 2, yeast)-like 1 , XCAP-E homolog , chromosome-associated protein E , structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E , structural maintenance of chromosomes protein 2 , FGF-inducible protein 16 , SMC2 structural maintenance of chromosomes 2-like 1 , fibroblast growth factor inducible 16 , (XCAP-E) , chromosome assembly protein XCAP-E , chromosome scaffold protein ScII

GENE ID SPECIES
10592 Homo sapiens
14211 Mus musculus
321452 Danio rerio
397800 Xenopus laevis
396156 Gallus gallus
481637 Canis lupus familiaris
362519 Rattus norvegicus
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