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Structural Maintenance of Chromosomes 3 (SMC3) ELISA Kits

SMC3 belongs to the SMC3 subfamily of SMC proteins. Additionally we are shipping SMC3 Antibodies (79) and SMC3 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SMC3 SMC3 9126 Q9UQE7
Anti-Mouse SMC3 SMC3 13006 Q9CW03
Anti-Rat SMC3 SMC3 29486  
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More ELISA Kits for SMC3 Interaction Partners

Human Structural Maintenance of Chromosomes 3 (SMC3) interaction partners

  1. De novo heterozygous mutations in SMC3 cause a range of Cornelia de Lange syndrome-overlapping phenotypes

  2. cohesin's proposed DNA exit gate is formed by interactions between Scc1 (show PTPRJ ELISA Kits) and the coiled-coil region of Smc3.

  3. Cross-sectional deep-sequencing analysis for clonal hierarchy demonstrated STAG2, SMC3, and RAD21 (show RAD21 ELISA Kits) mutations to be ancestral in 18%, 18%, and 47% of cases, respectively, and each expanded to clonal dominance concordant with disease transformation

  4. Mutations in SMC3 is associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  5. Upon knock-down of human SMC1, much of SMC3 remains stable, accumulates in the cytoplasm and does not associate with other cohesin proteins.

  6. c-MYC (show MYC ELISA Kits) down-regulation caused by cohesin mutations in SMC1A (show SMC1A ELISA Kits) and SMC3 genes may be an early/primary event in the pathogenesis of Cornelia de Lange syndrome.

  7. NIPBL (show NIPBL ELISA Kits), SMC1A (show SMC1A ELISA Kits), and SMC3 mutation-positive patients were equally likely to have congenital heart diseases in Cornelia de lange syndrome.

  8. SMC3 and separase (show ESPL1 ELISA Kits) are upregulated and securin (show PTTG1 ELISA Kits) is downregulated in malignant transformation of BEAS-2B cells induced by coal tar (show RBM8A ELISA Kits) pitch smoke extracts.

  9. these studies clearly suggest that bamacan interacts with the vaccinia virus-N1L and such interactions seem to play a positive role in promoting the viral growth and perhaps contribute to the virulence of VV in neural cells.

  10. The identification of 14 additional mutations of the cohesin complex genes NIPBL (show NIPBL ELISA Kits) and SMC1A (show SMC1A ELISA Kits) in a cohort of 30 unrelated patients with Cornelia de Lange syndrome, is reported.

Mouse (Murine) Structural Maintenance of Chromosomes 3 (SMC3) interaction partners

  1. A positively charged channel within the Smc1 (show SMC1A ELISA Kits)/Smc3 hinge required for sister chromatid cohesion.

Xenopus laevis Structural Maintenance of Chromosomes 3 (SMC3) interaction partners

  1. XEco2 (show ESCO2 ELISA Kits) is the cohesin acetyltransferase responsible for Smc3 acetylation.

  2. Endogenous SMC3 and newly expressed hRAD21 (show RAD21 ELISA Kits) co-localize on chromosomal axes, sites where sister chromatids are tightly paired. hRAD21 (show RAD21 ELISA Kits) recruitment to lampbrush chromosomes is modulated by chromosomal SMC1 (show SMC1A ELISA Kits) and SMC3.

SMC3 Antigen Profile

Antigen Summary

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.

Gene names and symbols associated with SMC3

  • structural maintenance of chromosomes 3 (smc3) antibody
  • structural maintenance of chromosomes 3 (SMC3) antibody
  • structural maintenance of chromosomes 3 (Smc3) antibody
  • BAM antibody
  • bamacan antibody
  • BMH antibody
  • CDLS3 antibody
  • Cspg6 antibody
  • HCAP antibody
  • im:7142991 antibody
  • Mmip1 antibody
  • SMC-3 antibody
  • SMC3L1 antibody
  • SmcD antibody
  • wu:fb22e01 antibody
  • wu:fc30d07 antibody
  • xsmc3 antibody

Protein level used designations for SMC3

chondroitin sulfate proteoglycan 6 (bamacan) , SMC protein 3 , basement membrane-associated chondroitin proteoglycan , chromosome-associated polypeptide , structural maintenance of chromosomes protein 3 , chondroitin sulfate proteoglycan 6 , chromosome segregation protein SmcD , mad member-interacting protein 1 , structural maintenace of chromosomes 3 , cohesin complex subunit , bamacan , basement membrane chondroitin sulfate proteoglycan

100145671 Xenopus (Silurana) tropicalis
9126 Homo sapiens
13006 Mus musculus
324475 Danio rerio
399092 Xenopus laevis
395188 Gallus gallus
486886 Canis lupus familiaris
281729 Bos taurus
29486 Rattus norvegicus
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