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Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010].. Additionally we are shipping Structural Maintenance of Chromosomes 4 Antibodies (65) and Structural Maintenance of Chromosomes 4 Kits (6) and many more products for this protein.
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analysis of functional differences of SMC2 and SMC4 hinge domain between condensins and cohesin in DNA recognition
Results indicate that miR (show MLXIP Proteins)-124-5p may target the tumorigenesis gene, SMC4, which suggests that expression levels of miR (show MLXIP Proteins)-124-5p in plasma and FFPE samples.
Knockdown of SMC-4 expression significantly suppressed the proliferation.
SMC4 expression was significantly associated with tumor size, de-differentiation, advanced stages and vascular invasion of the primary liver cancers.
mutation analysis of hCAP-C & hCAP-E (show SMC2 Proteins) in leukemia-lymphoma cell lines including 8 pyothorax-associated lymphoma (PAL); 3 of 8 PAL cell lines have hCAP-C or hCAP-E (show SMC2 Proteins) heterozygous mutations, indicating condensin mutations are relatively frequent in PAL
silencing of transposons in the pericentromeric heterochromatin of Arabidopsis thaliana requires SMC4.
results reveal a critical role for AtCAP-C during cell division
Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.
SMC protein 4
, SMC4 structural maintenance of chromosomes 4-like 1
, XCAP-C homolog
, chromosome-associated polypeptide C
, structural maintenance of chromosomes protein 4
, MC4 structural maintenance of chromosomes 4-like 1
, chromosome assembly protein XCAP-C
, chromosome-associated protein C
, condensin complex subunit