anti-Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) Antibodies

SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. Additionally we are shipping SDHC Kits (5) and SDHC Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SDHC 66052 Q9CZB0
SDHC 289217  
SDHC 6391 Q99643
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Top anti-SDHC Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SDHC antibody, IHC(P) IHC(P): Human Gastric Cancer Tissue Anti-SDHC antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: HELA Tissue Lysate Lane 3: JURKAT Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SDHC Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti SDHC Polyclonal Antibody, Unconjugated (ABIN1385318) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (44.33 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SDHC on formalin-fixed paraffin-embedded human skeletal muscle (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

SDHC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Rat (Rattus)


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Top referenced anti-SDHC Antibodies

  1. Human Monoclonal SDHC Primary Antibody for ELISA, WB - ABIN520106 : Lemarie, Grimm: Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells. in Mitochondrion 2009 (PubMed)
    Show all 2 Pubmed References

More Antibodies against SDHC Interaction Partners

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) interaction partners

  1. Studies indicate that the Tet-mev-1 conditional transgenic system can induce mutated SDHC gene in complex II.

Human Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) interaction partners

  1. SDH (show SARDH Antibodies)-deficient gastrointestinal stromal tumors (GISTs) account for approximately 8% of gastric GISTs and are associated with a high rate of distant metastasis, regardless of conventional risk category.

  2. 31% of the paragangliomas in the French Canadian can be explained by the SDHC mutation (c.397C>T, p.[Arg133Ter]).

  3. For classification, tumors were characterized by SDHA (show SDHA Antibodies), B, C, or D (SDHX) mutations and other genetic and epigenetic alterations, including presence of mutations in germline

  4. Heterozygous germline deletions of up to 104 kb in size were identified in SDHB (show SDHB Antibodies), SDHC, SDHD (show SDHD Antibodies) and flanking genes in 20 paraganglioma-pheochromocytoma patients. The exact breakpoint could be determined in 16 paraganglioma-pheochromocytoma patients of which 15 were novel deletions

  5. According to international guidelines, SDHB (show SDHB Antibodies), SDHC, and SDHD (show SDHD Antibodies) genetic testing were performed in this patient, but not SDHA (show SDHA Antibodies), which would have been prescribed only after surgery, in case of SDHA (show SDHA Antibodies) negative immunohistochemistry

  6. Loss of the SDHC gene is associated with metastatic sympathetic paraganglioma.

  7. This report provides evidence that SDHC promoter methylation can cause Paragangliomas due to SDHC inactivation

  8. significant association with overall survival were confirmed for SDHC gene, SDHD (show SDHD Antibodies) gene and FH gene ... SDHC gene and FH gene were the primary factors contributing to the different overall survival time of colorectal carcinoma

  9. This study strengthens the etiological association of SDH (show SARDH Antibodies) genes with pituitary neoplasia, renal tumorigenesis, and gastric gastrointestinal stromal tumors. Also, pancreatic neuroendocrine tumor falls within the SDH (show SARDH Antibodies)-related tumor spectrum.

  10. The discovery of SDHC epimutation provides a unifying explanation for the pathogenesis of SDH (show SARDH Antibodies)-deficient gastrointestinal stromal tumors.

Cow (Bovine) Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) interaction partners

SDHC Antigen Profile

Protein Summary

This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with SDHC

  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SDHC) antibody
  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (sdhc) antibody
  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SdhC) antibody
  • succinate dehydrogenase complex, subunit C, integral membrane protein (Sdhc) antibody
  • 0610010E03Rik antibody
  • AI316496 antibody
  • AU019277 antibody
  • CYB560 antibody
  • CYBL antibody
  • PGL3 antibody
  • QPS1 antibody
  • SDH3 antibody
  • SDHC antibody

Protein level used designations for SDHC

succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa , ENSANGP00000017418-like protein , OXPHOS complex II cytochrome B560 subunit , succinate dehydrogenase C , succinate dehydrogenase cytochrome b560 subunit, mitochondrial , QPs-1 , QPs1 , integral membrane protein CII-3 , succinate dehydrogenase complex, subunit C , cytochrome B large subunit of complex II , integral membrane protein CII-3b , succinate dehydrgenase cytochrome b , succinate dehydrogenase 3, integral membrane subunit , succinate-ubiquinone oxidoreductase cytochrome B large subunit , succinate dehydrogenase complex subunit C

GENE ID SPECIES
478983 Canis lupus familiaris
496650 Xenopus (Silurana) tropicalis
719978 Macaca mulatta
747462 Pan troglodytes
100114948 Nasonia vitripennis
100126849 Sus scrofa
66052 Mus musculus
289217 Rattus norvegicus
6391 Homo sapiens
327696 Bos taurus
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