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Sucrase-Isomaltase (Alpha-Glucosidase) Proteins (SI)

SI encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. Additionally we are shipping Sucrase-Isomaltase (Alpha-Glucosidase) Antibodies (8) and Sucrase-Isomaltase (Alpha-Glucosidase) Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse SI SI 69983  
SI 6476 P14410
Rat SI SI 497756 P23739
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Top Sucrase-Isomaltase (Alpha-Glucosidase) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details

SI Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Sucrase-Isomaltase (Alpha-Glucosidase) (SI) Interaction Partners

Mouse (Murine) Sucrase-Isomaltase (Alpha-Glucosidase) (SI) interaction partners

  1. Core2 O-glycan structure is essential for expression of SI and DDP (show TIMM8A Proteins)-IV during intestinal cell differentiation.

  2. These suggest that induction of SI gene by the diet rich in carbohydrate is associated with acetylation of histone H3 (show HIST3H3 Proteins) and H4 as well as binding of HNF-1 (show HNF1A Proteins) and Cdx-2 (show CDX2 Proteins) on SI gene.

Human Sucrase-Isomaltase (Alpha-Glucosidase) (SI) interaction partners

  1. Core2 O-glycan structure is essential for expression of SI and DDP (show TIMM8A Proteins)-IV during intestinal cell differentiation.

  2. These results suggest that sucrase-isomaltase transcription might be unchanged or lower in maturity-onset diabetes of the young (MODY (show HNF4A Proteins)) type 3, but greater in MODY5 (show HNF1B Proteins).

  3. phenylalanine cluster is required for shielding a folding determinant in the extracellular domain of SI; substitution of a Q by a P at residue 1098 of sucrase disrupts this determinant and elicits retention of SI(Q1098P) in ER and cis (show CISH Proteins)-Golgi

  4. hepatocyte nuclear factor (HNF)-1alpha (show HNF1A Proteins) and HNF-1beta (show HNF1B Proteins) would contribute to constitutive expression of the SI gene in the differentiated state in Caco-2 cells

  5. glucose regulation of sucrase-isomaltase gene expression was attenuated in HNF-1alphaT539fsdelC cells, but was well maintained in empty vector & HNF-1betaR177X cells.Results suggest that HNF-1alpha (show HNF1A Proteins) participates in glucose regulation of SI gene expression.

Sucrase-Isomaltase (Alpha-Glucosidase) (SI) Protein Profile

Protein Summary

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.

Gene names and symbols associated with SI

  • sucrase-isomaltase, intestinal (Tsp_13316)
  • sucrase-isomaltase, intestinal (Tsp_01057)
  • sucrase isomaltase (alpha-glucosidase) (Sis)
  • sucrase-isomaltase (alpha-glucosidase) (SI)
  • sucrase-isomaltase (alpha-glucosidase) (Si)
  • sucrase-isomaltase, intestinal-like (LOC100623884)
  • 2010204N08Rik protein
  • SI protein
  • Si-s protein
  • SUCIMAL protein

Protein level used designations for SI

sucrase-isomaltase, intestinal , alpha-glucosidase , sucrase isomaltase, structural , sucrase-isomaltase , oligosaccharide alpha-1,6-glucosidase

GENE ID SPECIES
10899408 Trichinella spiralis
10905132 Trichinella spiralis
69983 Mus musculus
6476 Homo sapiens
100009093 Oryctolagus cuniculus
497756 Rattus norvegicus
100623884 Sus scrofa
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