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anti-Sulfatase Modifying Factor 1 (SUMF1) Antibodies

SUMF1 encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Additionally we are shipping SUMF1 Proteins (11) and SUMF1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SUMF1 285362 Q8NBK3
SUMF1 58911 Q8R0F3
SUMF1 362409  
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Top anti-SUMF1 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB SUMF1 Antibody (C-Term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. SUMF1 Antibody (C-Term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SUMF1 Antibody (C-Term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SUMF1 Antibody (C-Term) (ABIN653924) in Hela cell line lysates (35 µg/lane). SUMF1 (arrow) was detected using the purified polyclonal antibody. SUMF1 Antibody (C-Term) (ABIN653924) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details

SUMF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SUMF1 Antibodies

  1. Human Polyclonal SUMF1 Primary Antibody for EIA, FACS - ABIN955006 : Hara, Shiga, Nozaki, Mitsui, Takahashi, Ishiguro, Yomono, Kurisaki, Goto, Ikeuchi, Tsuji, Nishizawa, Onodera: Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families. in Neurology 2008 (PubMed)
    Show all 4 references for ABIN955006

  2. Cow (Bovine) Polyclonal SUMF1 Primary Antibody for EIA, WB - ABIN401525 : Oshikawa, Usami, Kato: Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. in Molecular vision 2009 (PubMed)

More Antibodies against SUMF1 Interaction Partners

Human Sulfatase Modifying Factor 1 (SUMF1) interaction partners

  1. SUMF1 catalyses a monooxygenase type of reaction.

  2. This detailed clinical description and follow-up of a cohort of patients, together with the molecular characterisation of their underlying defects, contribute to improved knowledge of multiple sulfatase (show ARSH Antibodies) deficiency.

  3. MSD (show MESDC2 Antibodies) presenting in the newborn period with hypotonia, apnoea, cyanosis and rolling eyes, hepato-splenomegaly and deafness. This patient was compound heterozygous for two so far undescribed SUMF1 mutations (c.191C > A; p.S64X and c.818A > G; p.D273G

  4. The complete kinetic parameters for both forms of FGE are described, along with a proposed mechanism for FGE catalysis that accounts for the copper-dependent activity.

  5. A novel missense mutation & an insertional truncating mutation in SUMF1 gene causing nultiple sulphatase deficiency.

  6. furin (show FURIN Antibodies)-mediated processing of FGE during secretion is a physiological means of higher eukaryotic cells to regulate FGE activity upon exit from the endoplasmic reticulum

  7. Phenotypic outcome in Multiple Sulfatase (show ARSH Antibodies) Deficiency depends on both residual FGE activity as well as protein stability.

  8. This study identified genetic variation of SUMF1 in genes associated with in vivo glutamate (show GRIN1 Antibodies) measured using 1H magnetic resonance spectroscopic imaging in the grey matter of patients with multiple sclerosis.

  9. mutational analysis of SUMF1 in 20 Multiple sulfatase (show ARSH Antibodies) deficiency patients of different ethnic origin

  10. characterization of the human Calpha (show PRKACA Antibodies)-formylglycine-generating enzyme

Mouse (Murine) Sulfatase Modifying Factor 1 (SUMF1) interaction partners

  1. Sumf1(-/-) astrocytes failed to support the survival and function of wild-type cortical neurons, suggesting a non-cell autonomous mechanism for neurodegeneration.

  2. Sumf1 controls hematopoietic stem progenitor cell differentiation and hematopoietic lineage development through FGF and Wnt (show WNT2 Antibodies) signaling.

  3. Sumf1 is indispensable for sulfatase (show ARSH Antibodies) activation in mice and mammals, differently from bacteria, have a single sulfatase (show ARSH Antibodies) modification system

SUMF1 Antigen Profile

Protein Summary

This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SUMF1

  • sulfatase modifying factor 1 (SUMF1) antibody
  • sulfatase modifying factor 1 (Sumf1) antibody
  • AA543204 antibody
  • AAPA3037 antibody
  • AI463102 antibody
  • AI851573 antibody
  • FGE antibody

Protein level used designations for SUMF1

C-alpha-formylglycine-generating enzyme 1 , FGly-generating enzyme , sulfatase-modifying factor 1 , sulfatase-modifying factor

GENE ID SPECIES
285362 Homo sapiens
58911 Mus musculus
362409 Rattus norvegicus
536435 Bos taurus
484681 Canis lupus familiaris
100514188 Sus scrofa
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