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SOCS2 Proteins

(Suppressor of Cytokine Signaling 2 (SOCS2))
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].
SOCS2 Protein (AA 1-198) (GST tag) SOCS2 Protein (AA 1-198) (GST tag) SOCS2 Protein (AA 1-198) (GST tag) (ABIN1320927)

SOCS2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SOCS2 Protein (AA 99-198) (GST tag) SOCS2 Protein (AA 99-198) (GST tag) SOCS2 Protein (AA 99-198) (GST tag) (ABIN1320929)

SOCS2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SOCS2 Protein (AA 1-198) (Strep Tag) SOCS2 Protein (AA 1-198) (Strep Tag) SOCS2 Protein (AA 1-198) (Strep Tag) (ABIN3077005)

Crystallography grade SOCS2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA

SOCS2 Proteins by Grade

Find SOCS2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SOCS2 Proteins by Origin

Find SOCS2 Proteins for a variety of species such as anti-Human SOCS2, anti-Rat SOCS2, anti-Sheep SOCS2. The species listed below are among those available. Click on a link to go to the corresponding products.

SOCS2 Proteins by Source

Here you will find SOCS2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SOCS2 Proteins by Protein Type

Here you can find SOCS2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SOCS2 Proteins by Application

Find SOCS2 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SOCS2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1320927
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320929
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3077005
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3131673
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505230
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408915
Quantity 100 μg
Datasheet Datasheet
Reactivity Sheep
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2854101
Quantity 100 μg
Datasheet Datasheet
Reactivity Sheep
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2854104
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475740
Quantity 1 mg
Datasheet Datasheet
Reactivity Pig
Source Yeast
Validations
Cat. No. ABIN1613554
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1613612
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SOCS2 Proteins

Sen, Peng, Woods, Wistuba, Bell, El-Naggar, Lai, Johnson: "STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 1, pp. 127-39, (2012) (PubMed).

Aliases for SOCS2 Proteins

suppressor of cytokine signaling 2 (SOCS2) Proteins
suppressor of cytokine signaling 1 (Socs1) Proteins
suppressor of cytokine signaling 2 (Socs2) Proteins
suppressor of cytokine signaling 2 (socs2) Proteins
death domain-containing protein CRADD (LOC100716104) Proteins
suppressor of cytokine signaling 2 S homeolog (socs2.S) Proteins
8030460M17 Proteins
AI527257 Proteins
AW108012 Proteins
CIS2 Proteins
cis2 Proteins
Cish1 Proteins
Cish2 Proteins
cish2 Proteins
Cradd Proteins
D130043N08Rik Proteins
hg Proteins
JAB Proteins
si:dkey-202b22.1 Proteins
Socs-1 Proteins
SOCS-2 Proteins
Socs-2 Proteins
socs-2 Proteins
socs2 Proteins
Socs2 Proteins
SSI-2 Proteins
ssi-2 Proteins
SSI2 Proteins
ssi2 Proteins
STATI2 Proteins
stati2 Proteins
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