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Suppressor of Ty 16 Homolog (S. Cerevisiae) (SUPT16H) ELISA Kits

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. Additionally we are shipping Suppressor of Ty 16 Homolog (S. Cerevisiae) Antibodies (73) and Suppressor of Ty 16 Homolog (S. Cerevisiae) Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SUPT16H SUPT16H 114741 Q920B9
Anti-Human SUPT16H SUPT16H 11198 Q9Y5B9
Anti-Rat SUPT16H SUPT16H 305851  
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More ELISA Kits for Suppressor of Ty 16 Homolog (S. Cerevisiae) Interaction Partners

Fruit Fly (Drosophila melanogaster) Suppressor of Ty 16 Homolog (S. Cerevisiae) (SUPT16H) interaction partners

  1. results show that FACT, a heterodimer of dSPT16 and dSSRP1 (show SSRP1 ELISA Kits), associates with GAGA factor through its dSSRP1 (show SSRP1 ELISA Kits) subunit & facilitates chromatin remodeling; interactions between GAGA factor and spt16 implicate the GAGA factor-FACT complex in Hox (show MSH2 ELISA Kits) gene expression

  2. results show that FACT, a complex that comprises Spt16 and SSRP1, is associated with actively transcribed RNA polymerase II genes on Drosophila polytene chromosomes

Mouse (Murine) Suppressor of Ty 16 Homolog (S. Cerevisiae) (SUPT16H) interaction partners

  1. FACT is required for TOP1 (show TOP1 ELISA Kits) binding to H3K4me3 at non-B DNA containing chromatin for the site-specific cleavage.

  2. The mouse Supt16h/Fact140 gene, encoding part of the FACT chromatin transcription complex, maps close to Tcra and is highly expressed in thymus

Human Suppressor of Ty 16 Homolog (S. Cerevisiae) (SUPT16H) interaction partners

  1. FACT is required for TOP1 (show TOP1 ELISA Kits) binding to H3K4me3 at non-B DNA containing chromatin for the site-specific cleavage.

  2. In the absence of FACT complex, SSRP1 (show SSRP1 ELISA Kits) and SPT16 mRNAs are unstable and inefficiently translated, making reactivation of FACT function unlikely in normal cells.

  3. SUPT16H and RNF40 (show RNF40 ELISA Kits) are required for proper DNA end resection and timely DNA repair after double-strand breaks.

  4. facilitates RNA polymerase II driven transcription by destabilizing nucleosomal structure so that one histone H2A-H2B dimer is removed during enzyme passage; possesses intrinsic histone chaperone activity and can deposit core histones onto DNA

  5. Results demonstrate that elongation by RNA polymerase II through the nucleosomal barrier is minimally dependent upon (1) FACT and (2) the recruitment of PAF and the H2B monoubiquitination machinery.

  6. FACT is an integral and conserved component of the endogenous replication machinery, and support a model in which the concerted action of helicase and chromatin-modifying activities promotes chromosome replication.

  7. yFACT and Set2 oppose one another during transcriptional initiation at a step involving DNA binding by TBP (show TBP ELISA Kits) and TFIIA (show GTF2A1 ELISA Kits).

  8. SSRP1 (show SSRP1 ELISA Kits) has Spt16-dependent and -independent roles in regulating gene transcription in human cells.

  9. Data establish FACT as the major regulator involved in H2AX exchange process that is modulated by H2AX phosphorylation and Spt16 ADP-ribosylation.

Suppressor of Ty 16 Homolog (S. Cerevisiae) (SUPT16H) Antigen Profile

Antigen Summary

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit\; this gene encodes the 140 kDa subunit.

Gene names and symbols associated with SUPT16H

  • FACT complex subunit spt16 (AOR_1_1808194) antibody
  • FACT complex subunit SPT16 (CC1G_05155) antibody
  • CG1828 gene product from transcript CG1828-RB (dre4) antibody
  • Spt16p (SPT16) antibody
  • FACT complex component Spt16 (predicted) (SPBP8B7.19) antibody
  • similar to S. cerevisiae SPT16 (YGL207W) RNA Pol II transcriptional elongation regulator involved in chromatin remodeling (SPT16) antibody
  • global regulator of transcription (SPT16) antibody
  • FACT (FAcilitates Chromatin Transcription) complex subunit, putative (SPT16) antibody
  • FACT complex subunit SPT16 (spt16) antibody
  • suppressor of Ty 16 (Supt16) antibody
  • suppressor of Ty 16 homolog (supt16h) antibody
  • suppressor of Ty 16 homolog (S. cerevisiae) (SUPT16H) antibody
  • suppressor of Ty 16 homolog (S. cerevisiae) (Supt16h) antibody
  • Cdc68 antibody
  • CG1828 antibody
  • DDBDRAFT_0204912 antibody
  • DDBDRAFT_0231753 antibody
  • DDB_0204912 antibody
  • DDB_0231753 antibody
  • Dmel\\CG1828 antibody
  • DRE4/dSPT16 antibody
  • dspt16 antibody
  • DUF140 antibody
  • Fact140 antibody
  • FACTP140 antibody
  • l(3)62Bg antibody
  • l(3)dre4 antibody
  • spt16 antibody
  • SPT16/CDC68 antibody
  • SSF1 antibody
  • Supt16h antibody

Protein level used designations for SUPT16H

FACT complex subunit spt16 , FACT complex subunit SPT16 , CG1828-PA , CG1828-PB , dre4-PA , dre4-PB , lethal(3)62Bg , supressor of Ty element 16 , FACT complex component Spt16 (predicted) , hypothetical protein , global regulator of transcription , FACT (FAcilitates Chromatin Transcription) complex subunit, putative , Facilitates Chromatin Transcription (FACT) subunit protein, putative , cell division control protein 68 orthologue, putative , chromatin remodelling protein, putative , transcription elongation factor, putative , FACT 140 kDa subunit , FACTp140 , chromatin-specific transcription elongation factor 140 kDa subunit , facilitates chromatin transcription complex subunit SPT16 , suppressor of Ty 16 homolog , DNA unwinding factor 140 kDa subunit , facilitates chromatin transcription complex subunit spt16 , DUF140 , facilitates chromatin remodeling 140 kDa subunit , hSPT16

GENE ID SPECIES
5988427 Aspergillus oryzae RIB40
6009951 Coprinopsis cinerea okayama7130
38248 Drosophila melanogaster
852665 Saccharomyces cerevisiae S288c
2541355 Schizosaccharomyces pombe 972h-
3642741 Candida albicans SC5314
3642787 Candida albicans SC5314
4850866 Scheffersomyces stipitis CBS 6054
8047758 Candida dubliniensis CD36
8623736 Dictyostelium discoideum AX4
114741 Mus musculus
562348 Danio rerio
399345 Xenopus laevis
11198 Homo sapiens
612874 Canis lupus familiaris
514989 Bos taurus
305851 Rattus norvegicus
100155525 Sus scrofa
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