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anti-Suppressor of Var1, 3-Like 1 (S. Cerevisiae) (SUPV3L1) Antibodies

Major helicase player in mitochondrial RNA metabolism. Additionally we are shipping Suppressor of Var1, 3-Like 1 (S. Cerevisiae) Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SUPV3L1 6832 Q8IYB8
SUPV3L1 338359 Q80YD1
SUPV3L1 294385 Q5EBA1
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Top anti-Suppressor of Var1, 3-Like 1 (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB SUPV3L1 Antibody (N-term) (ABIN1881857) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. SUPV3L1 Antibody (N-term) (ABIN1881857) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB SUPV3L1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated WB Western Blot analysis of SUPV3L1 expression in transfected 293T cell line by SUPV3L1 MaxPab polyclonal antibody.Lane 1: SUPV3L1 transfected lysate(86.46 KDa).Lane 2: Non-transfected lysate. SUPV3L1 MaxPab polyclonal antibody. Western Blot analysis of SUPV3L1 expression in human pancreas. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IP   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Mouse Un-conjugated WB   50 μg Log in to see 11 to 16 Days
$553.14
Details
Human Rabbit Un-conjugated   100 μL Log in to see 9 to 14 Days
$322.58
Details
Human Rabbit Un-conjugated FACS, IHC, WB   400 μL Log in to see 6 to 8 Days
$454.30
Details

SUPV3L1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,

Mouse (Murine)


Rat (Rattus)


Top referenced anti-Suppressor of Var1, 3-Like 1 (S. Cerevisiae) Antibodies

  1. Human Polyclonal SUPV3L1 Primary Antibody for FACS, IHC (p) - ABIN1881857 : Szczesny, Borowski, Brzezniak, Dmochowska, Gewartowski, Bartnik, Stepien: Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance. in Nucleic acids research 2010 (PubMed)
    Show all 5 references for ABIN1881857

  2. Cow (Bovine) Polyclonal SUPV3L1 Primary Antibody for WB - ABIN2775185 : Pereira, Mason, Szczesny, Maddukuri, Dziwura, Jedrzejczak, Paul, Wojcik, Dybczynska, Tudek, Bartnik, Klysik, Bohr, Stepien: Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality. in Mechanisms of ageing and development 2007 (PubMed)

More Antibodies against Suppressor of Var1, 3-Like 1 (S. Cerevisiae) Interaction Partners

Human Suppressor of Var1, 3-Like 1 (S. Cerevisiae) (SUPV3L1) interaction partners

  1. SUV3 bridges PNPase (show PNPT1 Antibodies) and mtPAP (show MTPAP Antibodies) to form a transient complex in modulating mt-mRNA poly(A) tail length depending on the mitochondrial matrix Pi level.

  2. Interaction between PNPase (show PNPT1 Antibodies) and hSuv3 is essential for efficient mitochondrial RNA degradation.

  3. Localisation of hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA.

  4. Human SUV3 is an ATP-dependent multiple-substrate helicase; in addition to dsRNA and dsDNA unwinding activity, SUV3-70 and SUV3-83 can unwind heteroduplexes of RNA and DNA.

  5. Suv3 protein interacts with HBXIP (show HBXIP Antibodies), previously identified as a cofactor of survivin (show BIRC5 Antibodies) in suppression of apoptosis

  6. Down-regulation of hSUV3 results in cell cycle perturbations and in apoptosis, which is both AIF (show AIFM1 Antibodies)- and caspase (show CASP3 Antibodies)-dependent, and proceeds with the induction of p53 (show TP53 Antibodies).

  7. Human SUV3 protein interacts with human WRN and BLM helicases. Silencing of the SUV3 gene in the human cell line HeLa resulted in elevation of homologous recombination as measured by the frequency of sister chromatid exchange during mitotic cell division.

  8. SUV3 is essential for maintaining proper mitochondrial function, likely through a conserved role in mitochondrial RNA regulation.

Mouse (Murine) Suppressor of Var1, 3-Like 1 (S. Cerevisiae) (SUPV3L1) interaction partners

  1. Spatial and temporal aspects of Supv3L1 promoter activity.

  2. Mice homozygous for Supv3L1 mutation die in utero before midgestation.

  3. Supv3L1 is important for the maintenance of the skin barrier. In addition, loss of Supv3L1 function leads to accelerated aging-like phenotypes.

Suppressor of Var1, 3-Like 1 (S. Cerevisiae) (SUPV3L1) Antigen Profile

Protein Summary

Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria\; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA (By similarity).

Gene names and symbols associated with SUPV3L1

  • suppressor of var1, 3-like 1 (S. cerevisiae) (SUPV3L1) antibody
  • suppressor of var1, 3-like 1 (S. cerevisiae) (Supv3l1) antibody
  • suppressor of var1, 3-like 1 (S. cerevisiae) (supv3l1) antibody
  • 6330443E10Rik antibody
  • SUV3 antibody
  • wu:fc19b02 antibody
  • wu:fe37e06 antibody

Protein level used designations for SUPV3L1

ATP-dependent RNA helicase SUPV3L1, mitochondrial , SUV3-like protein 1 , suppressor of var1 3-like protein 1 , suppressor of var1, 3-like 1(SUV3)

GENE ID SPECIES
6832 Homo sapiens
505988 Bos taurus
338359 Mus musculus
294385 Rattus norvegicus
423697 Gallus gallus
570852 Danio rerio
Selected quality suppliers for anti-Suppressor of Var1, 3-Like 1 (S. Cerevisiae) (SUPV3L1) Antibodies
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