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Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) ELISA Kits

SUV39H1 is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. Additionally we are shipping Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Antibodies (88) and Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SUV39H1 SUV39H1 6839 O43463
Anti-Mouse SUV39H1 SUV39H1 20937 O54864
Anti-Rat SUV39H1 SUV39H1 302553  
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More ELISA Kits for Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Interaction Partners

Human Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. we describe the synthesis of multidomain 'designer chromatin' templates and their application to dissecting the regulation of human Suv39h1

  2. These results suggest a model in which SUV39H1 downregulation promotes the establishment of cellular senescence.

  3. CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1 (show DEFA1 ELISA Kits)/DNMT3A (show DNMT3A ELISA Kits) in DNA methylation (show HELLS ELISA Kits)-based epigenetic silencing

  4. PHF2 (show PHF1 ELISA Kits) is likely to repress rDNA transcription by competing with PHF8 (show PHF8 ELISA Kits) for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1.

  5. High SUV39H1 expression is associated with hepatocellular carcinoma.

  6. Suv39H1 induced apoptosis and inhibited cell proliferation in the gastric cancer MGC803 cell line, while decreasing BCL-2 (show BCL2 ELISA Kits), pro-caspase-9 (show CASP9 ELISA Kits), pro-caspase-3 (show CASP3 ELISA Kits) and C-myc (show MYC ELISA Kits). Suv39H1 may be a potential gene target for anti-gastric carcinoma therapy.

  7. SUV39H1 expression was upregulated in glioma cell lines and in glioma tissues compared to normal brain, being positively correlated with grade and histological malignancy.

  8. Short-chain fatty acids from periodontal pathogens suppress EZH2 (show EZH2 ELISA Kits), and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication.

  9. Results suggest that by regulating JMJD2b and SUV39H1 expression, p53 (show TP53 ELISA Kits) not only controls transcription but also promotes HC relaxation to accelerate a rate-limiting step in the repair of complex genomes.

  10. The SUV39H1 chromodomain was shown to recognize histone H3K9me2/3 specifically.

Mouse (Murine) Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. Oct4P4 lncRNA forms a complex with the SUV39H1 HMTase to direct the imposition of H3K9me3 and HP1alpha (show CBX5 ELISA Kits) to the promoter of the ancestral Oct4 (show POU5F1 ELISA Kits) gene, located on chromosome 17, leading to gene silencing and reduced mESC self-renewal.

  2. Provide genetic evidence that Suv39h1 controls telomere homeostasis and mediates resistance to oncogenic stress in vivo, conferring resistance to skin carcinogenesis.

  3. Repeat-associated, Suv39h-dependent H3K9me3 displays a dynamic distribution that differs in the epigenome of pluripotent versus more committed cells.

  4. These findings indicate that Suv39h1 enhances AP-2alpha (show TFAP2A ELISA Kits)-mediated transcriptional repression of C/EBPalpha (show CEBPA ELISA Kits) in an epigenetic manner and further inhibits adipocyte differentiation.

  5. A-type lamins interact with SUV39H1, and prelamin A/progerin exhibits enhanced binding capacity to SUV39H1, protecting it from proteasomal degradation and, consequently, increasing H3K9me3 levels.

  6. Data indicate that loss of suv39h1 prevents Myc (show MYC ELISA Kits)-induced chromosomal instability.

  7. Smads recruit H3K9 methyltransferases Suv39h1 to the IL-2 (show IL2 ELISA Kits) promoter, thereby inducing suppressive histone methylation and inhibiting T cell receptor-mediated IL-2 (show IL2 ELISA Kits) transcription.

  8. SirT1 (show SIRT1 ELISA Kits) preserves heterochromatin structure: it modulates Suv39h1 protein levels in stress conditions by preventing MDM2 (show MDM2 ELISA Kits)-mediated polyubiquitination at K87.

  9. novel role for microRNA in the epigenetic regulation of inflammatory genes in vascular smooth muscle cells of diabetic mice through downregulation of SUV39h1.

  10. Ring1B (show RNF2 ELISA Kits) and Suv39h1 have mutually exclusive roles in regulating distinct chromatin states at key developmental genes, and play a part in how lineage specification can be reinforced during early development

Zebrafish Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. The identification of a histone H3 (show HIST3H3 ELISA Kits) lysine 9 histone methyltransferase, SUV39H1, as a suppressor of embryonal rhabdomyosarcoma formation in zebrafish, is described.

  2. These results suggest that Dnmt1 (show DNMT1 ELISA Kits) activity helps direct histone methylation by Suv39h1 and that, together, Dnmt1 (show DNMT1 ELISA Kits) and Suv39h1 help guide the terminal differentiation of particular tissues.

Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) Antigen Profile

Antigen Summary

This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.

Gene names and symbols associated with SUV39H1

  • suppressor of variegation 3-9 homolog 1 (suv39h1) antibody
  • suppressor of variegation 3-9 homolog 1 (Drosophila) (SUV39H1) antibody
  • suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1) antibody
  • suppressor of variegation 3-9 homolog 1a (suv39h1a) antibody
  • AI852103 antibody
  • AL022883 antibody
  • DXHXS7466e antibody
  • fe02c04 antibody
  • H3-K9-HMTase 1 antibody
  • KMT1A antibody
  • MG44 antibody
  • mIS6 antibody
  • RGD1565028 antibody
  • SUV39H antibody
  • suv39h1 antibody
  • wu:fe02c04 antibody
  • zgc:101027 antibody

Protein level used designations for SUV39H1

histone-lysine N-methyltransferase SUV39H1 , su(var)3-9 homolog 1 , Su(var)3-9 homolog 1 , histone H3-K9 methyltransferase 1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 1 , lysine N-methyltransferase 1A , position-effect variegation 3-9 homolog , H3-K9-HMTase 1 , Suv39h histone methyltransferase , histone-lysine N-methyltransferase SUV39H1-A , su(var)3-9 homolog 1-A , suppressor of variegation 3-9 homolog 1 , suppressor of variegation 3-9 homolog 1-A , suppressor of variegation 3-9-like 1a

GENE ID SPECIES
431943 Xenopus laevis
6839 Homo sapiens
491868 Canis lupus familiaris
523047 Bos taurus
20937 Mus musculus
302553 Rattus norvegicus
100172621 Pongo abelii
445198 Danio rerio
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