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anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Antibodies

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. Additionally we are shipping SUV39H2 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SUV39H2 79723 Q9H5I1
SUV39H2 64707 Q9EQQ0
SUV39H2 364785  
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Top anti-SUV39H2 Antibodies at antibodies-online.com

Showing 10 out of 109 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-hSUV39H2-K315 Pab (ABIN388082) in 293 and HL60 cell line lysates (35 µg/lane). hSUV39H2-K315(arrow) was detected using the purified polyclonal antibody (1:62 dilution). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-SUV39H2 Pab (ABIN388081) is used in Western blot to detect SUV39H2 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SUV39H2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-SUV39H2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated ChIP, EIA, WB AP22371PU-N (1µg/ml) staining of Rat Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB SUV39H2 Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SUV39H2 antibody detected the SUV39H2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IP, WB Western blot analysis of SUV39H2 expression in HepG2 (A), A431 (B), HL60 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

SUV39H2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced anti-SUV39H2 Antibodies

  1. Human Polyclonal SUV39H2 Primary Antibody for IHC (p), WB - ABIN388081 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 4 references for ABIN388081

  2. Human Polyclonal SUV39H2 Primary Antibody for IHC (p), WB - ABIN388082 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 references for ABIN388082

  3. Human Polyclonal SUV39H2 Primary Antibody for ELISA, WB - ABIN184882 : Peters, OCarroll, Scherthan, Mechtler, Sauer, Schöfer, Weipoltshammer, Pagani, Lachner, Kohlmaier, Opravil, Doyle, Sibilia, Jenuwein: Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. in Cell 2001 (PubMed)

More Antibodies against SUV39H2 Interaction Partners

Human Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) interaction partners

  1. Our results reveal the regulatory mechanism of LSD1 (show KDM1A Antibodies) protein through its lysine methylation by SUV39H2 in human cancer cells

  2. We also demonstrate that the N324K mutant in the SET domain of SUV39H2 that has been shown to cause an inherited nasal skin disease in Labrador Retrievers renders SUV39H2 inactive

  3. Expression of JHDM2A (show KDM3A Antibodies) was significantly increased but HDAC2 (show HDAC2 Antibodies), HDAC7 (show HDAC7 Antibodies), and SUV39H2 were significantly down-regulated in Systemic Sclerosis B cells relative to controls

  4. genetic association studies in a Finnish population with type I diabetes: The minor T allele of exonic SNP rs17353856 in SUV39H2 is associated with diabetic retinopathy (in a larger meta-analysis); thus an genetic variation may be protective.

  5. findings suggest that Suv39H1 (show SUV39H1 Antibodies) and Suv39H2 are key hypoxia-induced methyltransferases; their decline in fetal lung during late gestation is critical for epigenetic changes resulting in the developmental induction of SP-A

  6. a novel SUV39H2 polymorphism may have a role in lung cancer susceptibility for smokers

  7. The SUV39H2 gene is found in tetrapods (e.g., human, mouse and frog) but not in zebrafish, suggesting that this gene is generated by a tetrapod lineage-specific gene duplication event.

Pig (Porcine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) interaction partners

  1. Knockdown of SUV39H1 (show SUV39H1 Antibodies) and SUV39H2 in embryonic stem-like cells and embryonic fibroblasts increases telomere length.

Mouse (Murine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) interaction partners

  1. Repeat-associated, Suv39h (show SUV39H1 Antibodies)-dependent H3K9me3 displays a dynamic distribution that differs in the epigenome of pluripotent versus more committed cells.

  2. ESET (show SETDB1 Antibodies) histone methyltransferase can form a large, multi-protein complex(es) with mSin3A/B co-repressors and HDAC1 (show HDAC1 Antibodies)/2 that participates in multiple pathways of transcriptional repression.

  3. Taken together, the results indicate epigenetic regulation of telomere length in mammals by Suv39h1 (show SUV39H1 Antibodies) and Suv39h2.

SUV39H2 Antigen Profile

Protein Summary

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes (By similarity).

Gene names and symbols associated with SUV39H2

  • suppressor of variegation 3-9 homolog 2 (Drosophila) (SUV39H2) antibody
  • suppressor of variegation 3-9 homolog 2 (suv39h2) antibody
  • similar to Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2) (SUV39H2) antibody
  • suppressor of variegation 3-9 homolog 2 (Drosophila) (Suv39h2) antibody
  • 4930507K23Rik antibody
  • AA536750 antibody
  • D030054H19Rik antibody
  • D2Ertd544e antibody
  • KMT1B antibody
  • SUV39H2 antibody

Protein level used designations for SUV39H2

suppressor of variegation 3-9 homolog 2 (Drosophila) , histone-lysine N-methyltransferase SUV39H2 , su(var)3-9 homolog 2 , histone-lysine N-methyltransferase SUV39H2-like , H3-K9-HMTase 2 , histone H3-K9 methyltransferase 2 , lysine N-methyltransferase 1B , Suv39h histone methyltransferase

GENE ID SPECIES
466014 Pan troglodytes
549262 Xenopus (Silurana) tropicalis
697378 Macaca mulatta
698451 Macaca mulatta
100037174 Xenopus laevis
100401513 Callithrix jacchus
100436926 Pongo abelii
100469547 Ailuropoda melanoleuca
100591032 Nomascus leucogenys
79723 Homo sapiens
477995 Canis lupus familiaris
664651 Sus scrofa
536936 Bos taurus
64707 Mus musculus
364785 Rattus norvegicus
426314 Gallus gallus
Selected quality suppliers for anti-SUV39H2 (SUV39H2) Antibodies
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