Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) ELISA Kits

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. Additionally we are shipping SUV39H2 Antibodies (114) and SUV39H2 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SUV39H2 SUV39H2 79723 Q9H5I1
Anti-Mouse SUV39H2 SUV39H2 64707 Q9EQQ0
Anti-Rat SUV39H2 SUV39H2 364785  
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More ELISA Kits for SUV39H2 Interaction Partners

Human Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) interaction partners

  1. histone H3 (show HIST3H3 ELISA Kits) lysine 9 methylation reduction, which may be due to the downregulation of methyltransferase SUV39H2 and the upregulation of demethylase (show MBD2 ELISA Kits) KDM4C (show KDM4C ELISA Kits), was found in CD4 (show CD4 ELISA Kits)(+) T lymphocytes of Latent autoimmune diabetes in adults patients

  2. data cannot finally exclude H2AX (show H2AFX ELISA Kits) methylation of SUV39H2 in cells, additional experimental evidence is required to validate this claim.

  3. Our results reveal the regulatory mechanism of LSD1 (show KDM1A ELISA Kits) protein through its lysine methylation by SUV39H2 in human cancer cells

  4. We also demonstrate that the N324K mutant in the SET domain of SUV39H2 that has been shown to cause an inherited nasal skin disease in Labrador Retrievers renders SUV39H2 inactive

  5. Expression of JHDM2A (show KDM3A ELISA Kits) was significantly increased but HDAC2 (show HDAC2 ELISA Kits), HDAC7 (show HDAC7 ELISA Kits), and SUV39H2 were significantly down-regulated in Systemic Sclerosis B cells relative to controls

  6. genetic association studies in a Finnish population with type I diabetes: The minor T allele of exonic SNP rs17353856 in SUV39H2 is associated with diabetic retinopathy (in a larger meta-analysis); thus an genetic variation may be protective.

  7. findings suggest that Suv39H1 (show SUV39H1 ELISA Kits) and Suv39H2 are key hypoxia-induced methyltransferases; their decline in fetal lung during late gestation is critical for epigenetic changes resulting in the developmental induction of SP-A

  8. a novel SUV39H2 polymorphism may have a role in lung cancer susceptibility for smokers

  9. The SUV39H2 gene is found in tetrapods (e.g., human, mouse and frog) but not in zebrafish, suggesting that this gene is generated by a tetrapod lineage-specific gene duplication event.

Pig (Porcine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) interaction partners

  1. Knockdown of SUV39H1 (show SUV39H1 ELISA Kits) and SUV39H2 in embryonic stem-like cells and embryonic fibroblasts increases telomere length.

Mouse (Murine) Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) interaction partners

  1. Data indicate that histone methyltransferase Suv39h2 expression is up-regulated in the liver in liver steatosis.

  2. Repeat-associated, Suv39h (show SUV39H1 ELISA Kits)-dependent H3K9me3 displays a dynamic distribution that differs in the epigenome of pluripotent versus more committed cells.

  3. ESET (show SETDB1 ELISA Kits) histone methyltransferase can form a large, multi-protein complex(es) with mSin3A/B co-repressors and HDAC1 (show HDAC1 ELISA Kits)/2 that participates in multiple pathways of transcriptional repression.

  4. Taken together, the results indicate epigenetic regulation of telomere length in mammals by Suv39h1 (show SUV39H1 ELISA Kits) and Suv39h2.

SUV39H2 Antigen Profile

Antigen Summary

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys- 9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes (By similarity).

Gene names and symbols associated with SUV39H2

  • suppressor of variegation 3-9 homolog 2 (Drosophila) (SUV39H2) antibody
  • suppressor of variegation 3-9 homolog 2 (suv39h2) antibody
  • similar to Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2) (SUV39H2) antibody
  • suppressor of variegation 3-9 homolog 2 (Drosophila) (Suv39h2) antibody
  • 4930507K23Rik antibody
  • AA536750 antibody
  • D030054H19Rik antibody
  • D2Ertd544e antibody
  • KMT1B antibody
  • SUV39H2 antibody

Protein level used designations for SUV39H2

suppressor of variegation 3-9 homolog 2 (Drosophila) , histone-lysine N-methyltransferase SUV39H2 , su(var)3-9 homolog 2 , histone-lysine N-methyltransferase SUV39H2-like , H3-K9-HMTase 2 , histone H3-K9 methyltransferase 2 , lysine N-methyltransferase 1B , Suv39h histone methyltransferase

466014 Pan troglodytes
549262 Xenopus (Silurana) tropicalis
697378 Macaca mulatta
698451 Macaca mulatta
100037174 Xenopus laevis
100401513 Callithrix jacchus
100436926 Pongo abelii
100469547 Ailuropoda melanoleuca
100591032 Nomascus leucogenys
79723 Homo sapiens
477995 Canis lupus familiaris
664651 Sus scrofa
536936 Bos taurus
64707 Mus musculus
364785 Rattus norvegicus
426314 Gallus gallus
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