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Surfactant Protein A1 Proteins (SFTPA1)

SFTPA1 encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. Additionally we are shipping Surfactant Protein A1 Antibodies (81) and Surfactant Protein A1 Kits (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SFTPA1 922 O43866
SFTPA1 14658 P48168
SFTPA1 24773 P08427
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Top Surfactant Protein A1 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$855.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Horse His tag   1 mg Log in to see 56 to 66 Days
$2,572.17
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$2,572.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,572.17
Details
Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days
$2,572.17
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,575.83
Details

SFTPA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)
,
Rat (Rattus) ,
,

More Proteins for Surfactant Protein A1 (SFTPA1) Interaction Partners

Human Surfactant Protein A1 (SFTPA1) interaction partners

  1. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  2. SP-A in exhaled particles from small airways may represent a promising non-invasive biomarker of disease in chronic obstructive pulmonary disease patients.

  3. AIM enhances intratubular debris clearance and ameliorates acute kidney injury via interaction with KIM-1 (show HAVCR1 Proteins).

  4. The present study provides the first evidence that apoptosis inhibitor of macrophages binds to IGFBP2, 3 and 4.

  5. CD36 (show CD36 Proteins) is involved in autophagy; the CD5L (show CD5L Proteins)-CD36 (show CD36 Proteins) axis has a role in the induction of macrophage autophagy

  6. In this study, the loci and haplotypes associated with pulmonary tuberculosis (PTB (show PTBP1 Proteins))were found mostly to be located in the SFTPA2 gene, suggesting that the effects of the SFTPA2 gene on PTB (show PTBP1 Proteins) are stronger than those of SFTPA1.

  7. CD5L (show CD5L Proteins) is a key protein in the control of immune homeostasis and inflammatory disease. (Review)

  8. Data suggest that that surfactant protein A (show GPR153 Proteins)(SP-A) levels may be important to maintain surfactant function in the presence of high cholesterol within surfactant.

  9. SP-A modulates lung immune system in the area of non-infectious lung diseases such as acute and chronic pulmonary fibrosis and lung cancer.

  10. 12 of which predicted to bind SP-A 3'UTRs.

Mouse (Murine) Surfactant Protein A1 (SFTPA1) interaction partners

  1. SP-A/D double knock-out mice showed increased susceptibility to urinary tract infection

  2. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  3. The presence of SP-A and SP-D (show SFTPD Proteins) in the murine decidua is likely to play a protective role against intrauterine infection during pregnancy.

  4. A species-specific thymine-to-guanine sequence variation in the Glrb (show GLRB Proteins) gene has been identified which gives rise to species-specific splice donor sites in the Glrb (show GLRB Proteins) genes of mouse and bushbaby.

  5. Data show that the type IV pilus (Tfp (show TRIM39 Proteins))-deficient mutant DeltapilA is severely attenuated in an acute pneumonia model of infection in the lungs of wild-type mice, but is virulent in the lungs of surfactant protein-A (show GPR153 Proteins) SP-A(-/-) mice.

  6. SP-A and SP-D (show SFTPD Proteins) attenuate kidney injury by modulating inflammation and apoptosis in sepsis-induced AKI.

  7. Maternal SP-A impacts milk sIgA and cytokine content, and is associated with improved newborn health.

  8. peptide from the interface with TLR4 (show TLR4 Proteins) inhibits endotoxic shock-like symptoms in a mouse model

  9. The SdpI (show PACSIN1 Proteins)-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta.

  10. Mice deficient in surfactant protein A (SP-A) and SP-D or in TLR2 manifest delayed parturition and decreased expression of inflammatory and contractile genes.

Pig (Porcine) Surfactant Protein A1 (SFTPA1) interaction partners

  1. Data suggest that transient exposure of surfactant to polymers like hyaluronan (HA) could be a promising strategy for the production of more efficient therapeutic surfactants SP-A, SP-B and SP-C (show SFTPC Proteins) preparations.

  2. PSP-A plays a significant physiological role as an antioxidant protecting the lung during the oxidative stress.

  3. Pulmonary surfactant-associated protein A (SP-A) is detected in thymus, trachea, lung, jejunum, and duodenum.

Cow (Bovine) Surfactant Protein A1 (SFTPA1) interaction partners

  1. gene encoding bovine surfactant protein A (show GPR153 Proteins) maps to the same locus on chromosome 28 as other collectins

Surfactant Protein A1 (SFTPA1) Protein Profile

Protein Summary

This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Surfactant Protein A1 Proteins (SFTPA1)

  • CD5 molecule-like (CD5L)
  • glycine receptor, beta subunit (Glrb)
  • surfactant associated protein A1 (Sftpa1)
  • surfactant protein A1 (Sftpa1)
  • surfactant protein A1 (SFTPA1)
  • AI853901 protein
  • AIM protein
  • API6 protein
  • COLEC4 protein
  • Glyrb protein
  • PRO229 protein
  • PSAP protein
  • PSP-A protein
  • PSPA protein
  • Sftp-1 protein
  • SFTP1 protein
  • Sftpa protein
  • SFTPA1B protein
  • SFTPA2 protein
  • SFTPA2B protein
  • Sftpl protein
  • SP-a protein
  • SP-A1 protein
  • SP-ALPHA protein
  • SPA protein
  • SPA1 protein
  • Spalpha protein
  • spastic protein

Protein level used designations for Surfactant Protein A1 Proteins (SFTPA1)

CD5 antigen-like , CD5 antigen-like (scavenger receptor cysteine rich family) , CT-2 , apoptosis inhibitor 6 , igM-associated peptide , glycine receptor 58 kDa subunit , glycine receptor subunit beta , inhibitory glycine receptor , PSAP , PSP-A , pulmonary surfactant-associated protein A , surfactant pulmonary associated protein A1 , pulmonary surfactant protein A , Surfactant-associated protein 1 (pulmonary surfactant protein SP-A) , Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A) , surfactant associated protein A , surfactant, pulmonary-associated protein A1 , SP-A , 35 kDa pulmonary surfactant-associated protein , alveolar proteinosis protein , collectin-4 , pulmonary surfactant-associated protein A1 , surfactant protein A1 variant AB'D' 6A , surfactant protein A1 variant AB'D' 6A2 , surfactant protein A1 variant AB'D' 6A3 , surfactant protein A1 variant AB'D' 6A4 , surfactant protein A1 variant ACD' 6A , surfactant protein A1 variant ACD' 6A2 , surfactant protein A1 variant ACD' 6A3 , surfactant protein A1 variant ACD' 6A4 , surfactant protein A1 variant AD' 6A , surfactant protein A1 variant AD' 6A2 , surfactant protein A1 variant AD' 6A3 , surfactant protein A1 variant AD' 6A4 , surfactant protein A1B , surfactant, pulmonary-associated protein A1A , surfactant, pulmonary-associated protein A1B , surfactant protein A , surfactant protein A2B , surfactant, pulmonary-associated protein A2 , surfactant, pulmonary-associated protein A2B , surfactant, pulmonary-associated protein A

GENE ID SPECIES
922 Homo sapiens
14658 Mus musculus
20387 Mus musculus
100135615 Cavia porcellus
24773 Rattus norvegicus
397503 Sus scrofa
653509 Homo sapiens
100009044 Oryctolagus cuniculus
407213 Bos taurus
610540 Canis lupus familiaris
100033826 Equus caballus
443033 Ovis aries
574108 Macaca mulatta
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