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Surfactant Protein C (SFTPC) ELISA Kits

SFTPC encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Additionally we are shipping Surfactant Protein C Antibodies (107) and Surfactant Protein C Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SFTPC 20389  
SFTPC 6440 P11686
SFTPC 50683 P11685
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Top Surfactant Protein C ELISA Kits at

Showing 10 out of 44 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 2.34 pg/mL 9.37-600 pg/mL   96 Tests Log in to see 9 to 11 Days
Pig 1.56 ng/ml 6.25-400 ng/mL   96 Tests Log in to see 9 to 11 Days
Cow 3.12 ng/ml 12.5-800 ng/mL   96 Tests Log in to see 9 to 11 Days
Rat 0.94 ng/mL 1.56-100 ng/mL Diagramm of the ELISA kit to detect Rat SPCwith the optical density on... 96 Tests Log in to see 8 to 9 Days
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  96 Tests Log in to see 11 to 13 Days
Guinea Pig
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Top referenced Surfactant Protein C ELISA Kits

  1. Human Surfactant Protein C ELISA Kit for Sandwich ELISA - ABIN365768 : Uhl, Vierkotten, Wagner, Burgstaller, Costa, Koch, Lindner, Meiners, Eickelberg, Königshoff: Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures. in The European respiratory journal 2015 (PubMed)
    Show all 2 references for ABIN365768

More ELISA Kits for Surfactant Protein C Interaction Partners

Xenopus laevis Surfactant Protein C (SFTPC) interaction partners

Mouse (Murine) Surfactant Protein C (SFTPC) interaction partners

  1. Data suggests that different SP-C mutations have unique consequences for interstitial lung diseases. Mutations here resulted in aberrant proSP-c products

  2. In vivo deficiency of SP-C leads to inflammation, increased cytokine production by type II cells, and persistent inflammation after repetitive LPS (show TLR4 ELISA Kits) stimulation.

  3. Transgenic restoration of SP-C reduces inflammation and improves viral clearance in the lungs of SP-C deficient mice.

  4. The SPC H2B-GFP allele allowed the FACS-based enrichment and gene expression profiling of AT2 cells.

  5. misfolded surfactant protein C has a role in endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells

  6. Cytoprotective-selective activated protein C (show PROC ELISA Kits) attenuates Pseudomonas aeruginosa-induced lung injury in mice

  7. The differential expression of mRNA by both airway level and lung region was determined for surfactant protein C.

  8. To target type II alveolar epithelial cells with this model, we generated transgenic mice that express DTR (show HBEGF ELISA Kits) off of the type II cell-specific surfactant protein C (SPC) promoter.

  9. Nedd4-2-mediated ubiquitination regulates lumenal relocation of SP-C, leading to processing and, ultimately, secretion of SP-C.

  10. pulmonary surfactant protein C binds with CD14 (show CD14 ELISA Kits) and lipopolysaccharide

Human Surfactant Protein C (SFTPC) interaction partners

  1. We sequenced SFTPC and analyzed morphology, ultrastructure and SP expression in lung tissue when available. We identified eight subjects who were heterozygous for SP-C mutations.

  2. analysis of clinical patterns in patients with SFTPC mutations

  3. support a chaperone function of the BRICHOS domain, possibly together with the linker region, during pro-SP-C biosynthesis in the endoplasmic reticulum

  4. cleavage of BRICHOS in a loop region that is cleaved during proSP-C biosynthesis results in increased capacity to delay Abeta (show APP ELISA Kits)(42) fibril formation.

  5. Structural modeling of transmembrane (BRICHOS) domains of SFTPC precursor and BRI2/ITM2B (integral membrane protein 2B (show ITM2B ELISA Kits)) identifies conserved region structurally complementary to beta-sheet-/amyloid-prone regions in BRICHOS domain-containing proteins.

  6. (surfactant protein C), a specific functional marker of human type II alveolar epithelial cells, was detected in differentiated cells by RT-PCR (reverse transcription-PCR) analysis after day 15.

  7. Several genetic abnormalities have been associated with familial pulmonary fibrosis. The present study examined the genes coding for surfactant protein-C, ATPbinding cassette protein A3 and telomerase, and found no abnormalities.

  8. Mutation increases endoplasmic reticulum stress and induces apoptotic cell death compared with wild-type SP-C in alveolar type II cells, supporting the significance of this mutation in the pathogenesis of pulmonary fibrosis.

  9. Data show that, in contrast to its wild-type counterpart, SP-C(I73T) is misdirected to the plasma membrane and subsequently internalized to the endocytic pathway via early endosomes, leading to the accumulation of abnormally processed proSP-C isoforms.

  10. Our study indicates that missense single nucleotide polymorphisms and haplotypes of SFTPA1 (show SFTPA1 ELISA Kits), SFTPA2 and SFTPD (show SFTPD ELISA Kits) are associated with susceptibility to community-acquired pneumonia(CAP), and that several haplotypes also influence severity and outcome of CAP.

Cow (Bovine) Surfactant Protein C (SFTPC) interaction partners

  1. The hydrophobic surfactant proteins SP-B and SP-C induce formation of bicontinuous inverse cubic phases.

Pig (Porcine) Surfactant Protein C (SFTPC) interaction partners

  1. Data indicate that surfactant protein C (SP-C) structure does not seem altered by palmitoylation or the lipid environment.

  2. Data suggest that transient exposure of surfactant to polymers like hyaluronan (HA) could be a promising strategy for the production of more efficient therapeutic surfactants SP-A (show SFTPA1 ELISA Kits), SP-B and SP-C preparations.

  3. SP-B and SP-C proteins promote the formation of proteolipid channels in which lipid molecules are functionally involved.

  4. Palmitoylation is key for the functional cooperation of SP-C with SP-B that enables cholesterol-containing surfactant films to reach very low tensions under compression.

  5. Surfactant protein SP-B promoted film formation and reextension to lower surface tensions than SP-C.

  6. finds evidence of an interaction between cholesterol-enriched phases and SP-C, and confirms that physiological concentrations of cholesterol do not have any detrimental effect on lung surfactant with a proper lipid and protein composition

  7. study the effects of the interaction of SP-C with Dipalmitoleoylphosphatidylethanolamine on the adsorption and interfacial disintegration of phospholipid lamellar and non-lamellar phases and on the phase coexistence in insoluble DPoPE monomolecular films

Surfactant Protein C (SFTPC) Antigen Profile

Antigen Summary

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Gene names and symbols associated with Surfactant Protein C (SFTPC) ELISA Kits

  • surfactant protein C (SFTPC) antibody
  • surfactant protein C (LOC779071) antibody
  • surfactant, pulmonary-associated protein C (sftpc) antibody
  • surfactant associated protein C (Sftpc) antibody
  • surfactant protein C (Sftpc) antibody
  • BRICD6 antibody
  • pro-SpC antibody
  • PSP-C antibody
  • Sftp-2 antibody
  • SFTP2 antibody
  • SFTPC antibody
  • SMDP2 antibody
  • SP-C antibody
  • SP5 antibody
  • SPC antibody
  • xSP-C antibody

Protein level used designations for Surfactant Protein C (SFTPC) ELISA Kits

surfactant protein C , surfactant, pulmonary-associated protein C , pulmonary surfactant-associated protein C , pulmonary surfactant-associated proteolipid SPL(Val) , BRICHOS domain containing 6 , SP5 , pulmonary surfactant apoprotein-2 SP-C , SP-C , Surfactant pulmonary-associated protein C , Surfactant, pulmonary-associated protein C , surfactant associated protein C , type I SP-C , type II SP-C

464041 Pan troglodytes
779071 Xenopus laevis
100038236 Xenopus (Silurana) tropicalis
20389 Mus musculus
6440 Homo sapiens
282071 Bos taurus
50683 Rattus norvegicus
443034 Ovis aries
100009162 Oryctolagus cuniculus
733580 Sus scrofa
477385 Canis lupus familiaris
707696 Macaca mulatta
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