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anti-Surfeit 1 (SURF1) Antibodies

SURF1 encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. Additionally we are shipping SURF1 Proteins (10) and SURF1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SURF1 6834 Q15526
SURF1 64463 Q9QXU2
SURF1 20930 P09925
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Top anti-SURF1 Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using SURF1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SURF1 AntibodyTitration: 1.0 µg/mL  Positive Control: HepG2 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of SURF1 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of SURF1 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated WB Western Blot analysis of SURF1 expression in transfected 293T cell line by SURF1 MaxPab polyclonal antibody.Lane1:SURF1 transfected lysate(33 KDa).Lane2:Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 8 to 10 Days
$522.50
Details

SURF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,

Rat (Rattus)


Mouse (Murine)


Top referenced anti-SURF1 Antibodies

  1. Human Polyclonal SURF1 Primary Antibody for WB - ABIN955011 : St-Pierre, Liu, Kha, Zhu, Ryan, Jiang, Zacksenhaus: Conserved and specific functions of mammalian ssu72. in Nucleic acids research 2005 (PubMed)
    Show all 3 references for ABIN955011

More Antibodies against SURF1 Interaction Partners

Human Surfeit 1 (SURF1) interaction partners

  1. Mutations in the SURF1 gene are a cause of Charcot-Marie-Tooth disease.

  2. This study suggested that hypertrophic olivary degeneration on magnetic resonance imaging in mitochondrial syndromes associated with POLG (show POLG Antibodies) and SURF1 mutations.

  3. sequenced the SURF1 gene and identified two heterozygous mutations; c.49+1 G>T and c.752_753del in Case 1, and homozygous c.743 C>A in Case 2

  4. Study identified 21 patients with clinical features of Leigh syndrome who are either homozygous or compound heterozygous for SURF1 mutations.

  5. Analysis of fibroblast cell lines from 9 patients with SURF1 mutations revealed a 70% decrease of the COX (show COX8A Antibodies) complex content to be associated with 32-54% upregulation of respiratory chain complexes I, III and V and accumulation of Cox5a (show COX5A Antibodies) subunit.

  6. Analysis of mutations in the SURF1 homolog Shy1 revealed Coa4, a new member of the cytochrome oxidase assembly factor family.

  7. Three novel mutations of the SURF-1 gene were identified in Japanese patients with cytochrome c (show CYCS Antibodies) oxidase deficiency; loss of function of the SURF-1 protein; cytochrome c (show CYCS Antibodies) oxidase activity was decreased to less than 20% of the control mean.

  8. new missense mutation of 574C>T in the SURF1 gene in Leigh's syndrome

  9. Two novel pathogenic SURF1 mutations have been identified in a patient with Leigh syndrome.

  10. Mutations in the nuclear SURF1 gene are specifically associated with cytochrome c (show CYCS Antibodies) oxidase (COX (show COX8A Antibodies))-deficient Leigh syndrome. MR imaging abnormalities in three children with this condition involved the brain.

Mouse (Murine) Surfeit 1 (SURF1) interaction partners

  1. These findings suggest that Surf1 deficiency-induced metabolic alterations may have positive effects on brain function.

  2. The expression of peroxisome proliferator-activated receptor gamma-coactivator 1-alpha (PGC-1alpha (show PPARGC1A Antibodies)) mRNA and protein was up-regulated in white adipose tissue from Surf1-/- mice, and the expression of PGC-1alpha (show PPARGC1A Antibodies) target genes

  3. Compared to wild type (WT) preparations Surf1 knockout preparations had a higher baseline respiratory frequency and abnormal responses to hypoxia and hypercapnia that involved both respiratory frequency and motor nerve discharge pattern.

  4. murine Surf1 protein (Surf1p) has a function specifically related to cytochrome c (show CYCS Antibodies) oxidase

  5. Prolonged lifespan and complete protection from Ca(2 (show CA2 Antibodies)+)-dependent neurotoxicity induced by kainic acid in Surf-1 knockout mice.

SURF1 Antigen Profile

Protein Summary

This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Gene names and symbols associated with anti-Surfeit 1 (SURF1) Antibodies

  • Surfeit 1 (Surf1) antibody
  • surfeit 1 (Surf1) antibody
  • surfeit 1 (SURF1) antibody
  • surfeit 1 (surf1) antibody
  • surfeit gene 1 (Surf1) antibody
  • Surfeit locus 1 cytochrome c oxidase biogenesis protein (SURF1) antibody
  • 0610010F23Rik antibody
  • Ab1-205 antibody
  • BcDNA:GH23574 antibody
  • CG9943 antibody
  • Dmel\\CG9943 antibody
  • GB14201 antibody
  • im:6898613 antibody
  • Surf-1 antibody
  • SURF1 antibody
  • SURFEIT 1 antibody
  • zgc:158646 antibody

Protein level used designations for anti-Surfeit 1 (SURF1) Antibodies

CG9943-PA , Surf1-PA , surfeit 1 , surfeit locus protein 1 , surfeit protein

GENE ID SPECIES
44498 Drosophila melanogaster
413781 Apis mellifera
480681 Canis lupus familiaris
557970 Danio rerio
693110 Bombyx mori
6834 Homo sapiens
64463 Rattus norvegicus
417157 Gallus gallus
20930 Mus musculus
821310 Arabidopsis thaliana
Selected quality suppliers for anti-SURF1 (SURF1) Antibodies
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