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BIRC5 is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. Additionally we are shipping Survivin Kits (45) and Survivin Proteins (17) and many more products for this protein.
Showing 10 out of 378 products:
Human Polyclonal Survivin Primary Antibody for ELISA, WB - ABIN185270
Li, Ambrosini, Chu, Plescia, Tognin, Marchisio, Altieri: Control of apoptosis and mitotic spindle checkpoint by survivin. in Nature 1999
The present studies aim to examine whether and how cilia function (Pkd1 (show PKD1 Antibodies) or Pkd2 (show PKD2 Antibodies)) and structure (Tg737 (show IFT88 Antibodies)) play a role in cystic kidney and aneurysm through survivin downregulation.
Survivin 1 was identified as a key regulator of neurogenesis, vasculo-angiogenesis, hematopoiesis and cardiogenesis.
the Aurora B (show AURKB Antibodies) chromosome passenger protein complex, including INCENP (show INCENP Antibodies) and survivin, is regulated during oocyte maturation in Xenopus laevis
Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.
In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Antibodies) and ki67 (show MKI67 Antibodies).
survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.
Survivin directly participates in PRL (show PRL Antibodies)-mediated beta cell proliferation via Akt (show AKT1 Antibodies), STAT5 (show STAT5A Antibodies)-PIM (show PIM1 Antibodies) and ERK (show EPHB2 Antibodies) signalling pathways during pregnancy
Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.
Results suggest a role for survivin in regulating adult neural precursor activity and inhibiting apoptosis or programmed cell death in the dentate gyrus following brain injury
NR4A1 (show NR4A1 Antibodies) protects pancreatic beta-cells against endoplasmic reticulum stress-mediated apoptosis by up-regulating Survivin expression and down-regulating CHOP (show DDIT3 Antibodies) expression.
Studies indicate the importance of survivin in Sonic hedgehog (SHH (show SHH Antibodies))-driven medulloblastoma (MB).
the Skp1 (show SKP1 Antibodies).Cul1 (show CUL1 Antibodies).F-box protein (show FBXO30 Antibodies) complex subunit Fbxl7 (show FBXL7 Antibodies) modulates mitochondrial function by controlling the cellular abundance of survivin
Both HIF1-alpha (show HIF1A Antibodies) and survivin are involved in the retinal neovascularization in oxygen-induced retinopathy.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. In humans, gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts have been identified in human that regulate this gene's expression. At least three transcript variants encoding distinct isoforms have been found for this gene, although at least one of these transcript variants is a nonsense-mediated decay (NMD) candidate.
baculoviral IAP repeat-containing protein 5
, survivin 1
, baculoviral IAP repeat-containing protein 5.1
, Survivin 2
, baculoviral IAP repeat-containing 5, gene 2
, baculoviral IAP repeat-containing protein 5.2
, baculoviral IAP repeat-containing 5
, apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5 (survivin)
, apoptosis inhibitor 4