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anti-Survivin (BIRC5) Antibodies

BIRC5 is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. Additionally we are shipping Survivin Kits (37) and Survivin Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BIRC5 11799 O70201
BIRC5    
BIRC5    
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Top anti-Survivin Antibodies at antibodies-online.com

Showing 10 out of 406 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IF, IHC, IHC (fro), IHC (p), WB Staing of ovary, cancer using ABIN153038. Detection of Survivin in HeLa whole cell extract using ABIN153038. 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Hamster Mouse Un-conjugated ICC, IF, IHC (p), IP, IHC, ELISA, WB Staining of human lung, cancer using ABIN153037. 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IF, IHC (fro), IHC (p), IP, WB Survivin detected in rat aorta smooth muscle cell lysate using ABIN153011. Flow Cytometry: Survivin Antibody (60.11) [ABIN153011] - Staining of NTERA-2 cells using ABIN153011 at a 1:2000 dilution detected using Dylight-488 conjugated goat anti-mouse IgG secondary antibody. 0.1 mL Log in to see 5 to 7 Days
$381.94
Details
Human Goat Un-conjugated ELISA, WB ABIN185270 (0.01µg/ml) staining of Molt-4 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: Survivin [p Ser20] Antibody [ABIN4099727] - Detection of Survivin [Ser20] in phosphorylated recombinant protein (+), but not in unphosphorylated protein (-) using ABIN4099727. Immunocytochemistry/Immunofluorescence: Survivin [p Ser20] Antibody [ABIN4099727] - Survivin [p Ser20] antibody was tested in Hela cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Log in to see 5 to 7 Days
$381.94
Details
Human Mouse Un-conjugated BP, ELISA, FACS, ICC, IF, IHC, IHC (p), in vitro, Neut, WB 0.1 mL Log in to see 5 to 7 Days
$381.94
Details
Human Mouse Fluorescein FACS Detection of Survivin in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human Survivin Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$315.00
Details
Human Rabbit Un-conjugated ICC, IF, WB Lane 1: Phosphorylated Survivin protein and Lane 2: Non-phosphorylated Survivin protein. Immunocytochemistry/Immunofluorescence: Survivin [p Thr34] Antibody [ABIN153036] - Survivin antibody was tested in HeLa cells with FITC (green). Nuclei were counterstained with Dapi (blue). 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Cat Rabbit Un-conjugated ChIP, ELISA, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, SimWes, WB Telophase with accumulation of survivin in the midbodies of two daughter cells. Survivin detection using ABIN153009 0.1 mL Log in to see 5 to 7 Days
$447.56
Details
Gerbil Rabbit Un-conjugated IHC (fro), IHC (p), IP, IHC, WB Western blot analysis of Survivin using ABIN252166 at 1:2000.  Survivin was detected in the two tumor cell lines, Jurkat (T cell lymphoma) and  RS11846 (non-Hodgkin's lymphoma), but not in lysates from normal tissues. Survivin RP, full-length recombiant human survivin protein was used as a positive control. Immunohistochemical analysis of Survivin in formalin-fixed, paraffin-embedded human prostate and breast cancer using ABIN252166 at 1:2000.  A and A1, prostate cancer at low and high magnification, respectively. B and B1, breast cancer. B1 is a high magnification of an area of metastasis. Hematoxylin-eosin counterstain. 0.05 mL Log in to see 5 to 7 Days
$278.25
Details

BIRC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Survivin Antibodies

  1. Human Polyclonal Survivin Primary Antibody for ELISA, WB - ABIN185270 : Li, Ambrosini, Chu, Plescia, Tognin, Marchisio, Altieri: Control of apoptosis and mitotic spindle checkpoint by survivin. in Nature 1999 (PubMed)

  2. Human Monoclonal Survivin Primary Antibody for FACS - ABIN4898957 : Schneider, Costa, Legrand, Bigot, Lecleire, Grassi, Vannier, Vasse: In vitro secretion of matrix metalloprotease 9 is a prognostic marker in childhood acute lymphoblastic leukemia. in Leukemia research 2010 (PubMed)

  3. Human Monoclonal Survivin Primary Antibody for FACS - ABIN4895255 : Perabo, Frössler, Landwehrs, Schmidt, von Rücker, Wirger, Müller: Indirubin-3'-monoxime, a CDK inhibitor induces growth inhibition and apoptosis-independent up-regulation of survivin in transitional cell cancer. in Anticancer research 2006 (PubMed)

More Antibodies against Survivin Interaction Partners

Zebrafish Survivin (BIRC5) interaction partners

  1. The present studies aim to examine whether and how cilia function (Pkd1 (show PKD1 Antibodies) or Pkd2 (show PKD2 Antibodies)) and structure (Tg737 (show IFT88 Antibodies)) play a role in cystic kidney and aneurysm through survivin downregulation.

  2. Survivin 1 was identified as a key regulator of neurogenesis, vasculo-angiogenesis, hematopoiesis and cardiogenesis.

Xenopus laevis Survivin (BIRC5) interaction partners

  1. the Aurora B (show AURKB Antibodies) chromosome passenger protein complex, including INCENP (show INCENP Antibodies) and survivin, is regulated during oocyte maturation in Xenopus laevis

Mouse (Murine) Survivin (BIRC5) interaction partners

  1. Survivin is a key regulator of gut (show GUSB Antibodies) tissue integrity by regulating epithelial homeostasis in the stem cell niche.

  2. TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (show WNT2 Antibodies) in CPCs to mediate cardioprotection and improve cardiac function.

  3. Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.

  4. In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Antibodies) and ki67 (show MKI67 Antibodies).

  5. survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.

  6. Survivin directly participates in PRL (show PRL Antibodies)-mediated beta cell proliferation via Akt (show AKT1 Antibodies), STAT5 (show STAT5A Antibodies)-PIM (show PIM1 Antibodies) and ERK (show EPHB2 Antibodies) signalling pathways during pregnancy

  7. Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.

  8. Results suggest a role for survivin in regulating adult neural precursor activity and inhibiting apoptosis or programmed cell death in the dentate gyrus following brain injury

  9. NR4A1 (show NR4A1 Antibodies) protects pancreatic beta-cells against endoplasmic reticulum stress-mediated apoptosis by up-regulating Survivin expression and down-regulating CHOP (show DDIT3 Antibodies) expression.

  10. Studies indicate the importance of survivin in Sonic hedgehog (SHH (show SHH Antibodies))-driven medulloblastoma (MB).

Survivin (BIRC5) Antigen Profile

Protein Summary

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. In humans, gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts have been identified in human that regulate this gene's expression. At least three transcript variants encoding distinct isoforms have been found for this gene, although at least one of these transcript variants is a nonsense-mediated decay (NMD) candidate.

Gene names and symbols associated with anti-Survivin (BIRC5) Antibodies

  • baculoviral IAP repeat-containing 5a (birc5a) antibody
  • survivin (LOC398389) antibody
  • baculoviral IAP repeat-containing 5 (BIRC5) antibody
  • baculoviral IAP repeat-containing 5, gene 1 (birc5.1) antibody
  • baculoviral IAP repeat containing 5 (birc5.2) antibody
  • survivin (AaeL_AAEL012446) antibody
  • survivin (CpipJ_CPIJ001663) antibody
  • survivin (CpipJ_CPIJ002689) antibody
  • survivin (CpipJ_CPIJ006694) antibody
  • baculoviral IAP repeat containing 5 (BIRC5) antibody
  • baculoviral IAP repeat-containing 5 (Birc5) antibody
  • AAC-11 antibody
  • Api4 antibody
  • BIR1 antibody
  • bir5a antibody
  • birc5 antibody
  • epr-1 antibody
  • LOC398389 antibody
  • SIX antibody
  • Su1 antibody
  • Su2 antibody
  • Survivin antibody
  • Survivin1 antibody
  • survivin40 antibody
  • svv1 antibody
  • svv2 antibody
  • TIAP antibody
  • XBIR1 antibody
  • xsurv antibody
  • xSurvivin antibody
  • xSurvivin1 antibody
  • xSurvivin2 antibody

Protein level used designations for anti-Survivin (BIRC5) Antibodies

baculoviral IAP repeat-containing protein 5 , survivin 1 , survivin , baculoviral IAP repeat-containing protein 5.1 , Survivin 2 , TGas101d21.1 , baculoviral IAP repeat-containing 5, gene 2 , baculoviral IAP repeat-containing protein 5.2 , baculoviral IAP repeat-containing 5 , apoptosis inhibitor survivin , baculoviral IAP repeat-containing 5 (survivin) , apoptosis inhibitor 4

GENE ID SPECIES
373110 Danio rerio
398389 Xenopus laevis
403540 Canis lupus familiaris
733532 Xenopus (Silurana) tropicalis
733575 Xenopus (Silurana) tropicalis
5576283 Aedes aegypti
6032633 Culex quinquefasciatus
6033880 Culex quinquefasciatus
6038455 Culex quinquefasciatus
100475314 Ailuropoda melanoleuca
442936 Canis lupus familiaris
493835 Felis catus
374078 Gallus gallus
11799 Mus musculus
100527953 Cavia porcellus
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