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SRPX2 encodes a secreted protein that contains three sushi repeat motifs. Additionally we are shipping SRPX2 Antibodies (53) and SRPX2 Kits (19) and many more products for this protein.
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Increased Sushi repeat-containing protein X-linked 2 is associated with progression of colorectal cancer.
In rolandic epilepsy patients no major role was found for an association with SRPX2 or ELP4 (show ELP4 Proteins) genes.
High SRPX2 expression is associated with gastric cancer.
SRPX2 is an epilepsy- and language-associated gene that is a target of the foxhead box protein P2 (FoxP2 (show FOXP2 Proteins)) transcription factor.
The SRPX2 protein contains the P-DUDES structural domain in its C-terminal region. This domain has significant albeit remote sequence similarity to thioredoxin-like (show TXN Proteins) domains, and is predicted to possess an oxidoreductase (show TXNRD1 Proteins) function.
Hypomethylation of SRPX2 appeared at the transition from adenoma to carcinoma, and was correlated with adenocarcinoma histology, microsatellite stability, and poor differentiation.
SRPX2 is a novel chondroitin sulfate proteoglycan (show Vcan Proteins) that is overexpressed in gastrointestinal cancer cells.
The FOXP2 (show FOXP2 Proteins)-SRPX2/uPAR (show PLAUR Proteins) network provides exciting insights into molecular pathways underlying speech-related disorders.
acts as regulator of ICAM1 (show ICAM1 Proteins) and E-selectin (show SELE Proteins) during endotoxemia
These findings suggest that Srpx2 regulates endothelial cell migration and tube formation and provides a new target for modulating angiogenesis.
This gene encodes a secreted protein that contains three sushi repeat motifs. The encoded protein may play a role in the development of speech and language centers in the brain. This protein may also be involved in angiogenesis. Mutations in this gene are the cause of bilateral perisylvian polymicrogyria, rolandic epilepsy, speech dyspraxia and mental retardation.
sushi repeat-containing protein SRPX2
, sushi-repeat protein up-regulated in leukemia
, sushi-repeat-containing protein, X-linked 2
, sushi-repeat containing protein