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Synaptic Vesicle Glycoprotein 2A Proteins (SV2A)

membrane glycoprotein\; acts as a synaptic vesicle-specific transporter [RGD, Feb 2006].. Additionally we are shipping SV2A Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SV2A 64051 Q9JIS5
Rat SV2A SV2A 117559 Q02563
SV2A 9900 Q7L0J3
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Top SV2A Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SV2A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Synaptic Vesicle Glycoprotein 2A (SV2A) Interaction Partners

Mouse (Murine) Synaptic Vesicle Glycoprotein 2A (SV2A) interaction partners

  1. This study reveals fundamental details of how phosphorylation of Thr84 on SV2A controls its interaction with synaptotagmin-1 (show SYT1 Proteins) and implicates SV2A as a phospho-dependent chaperone

  2. observed alterations of SV2A expression in hippocampus are consistent with the hypothesis that SV2A absence favors epileptic seizures around postnatal day 7

  3. Action potential- and Ca(2 (show CA2 Proteins)+) -dependent glutamatergic & GABAergic synaptic transmission are differentially altered in the hippocampus of SV2A-deficient mice, but the mechanism of exocytosis itself is not changed.

  4. Glycosylation is dispensable for sorting of synaptotagmin 1 (show SYT1 Proteins) but is critical for targeting of SV2 and synaptophysin (show SYP Proteins) to recycling synaptic vesicles.

  5. study suggests that SV2A specifically regulates hilar GABAergic neurotransmission in the kindled hippocampus probably as a compensatory or prophylactic mechanism against kindling epileptogenesis

  6. Loss of synaptic vesicle glycoprotein 2a is associated with inhibition of tetanus neurotoxin into central neurons.

  7. These results indicate that SV2 performs at least two actions at the synapse that contribute to neurotransmitter release.

  8. SV2A is selectively localized in motor nerve terminals on slow (type I and small type IIA) muscle fibers.

  9. SV2 action modulates synaptic networks by ensuring that low-frequency neurotransmission is faithfully conveyed.

  10. findings show that botulinum neurotoxin (BoNT/A) enters neurons by binding to the synaptic vesicle protein SV2 (isoforms A, B, and C);SV2 acts as the protein receptor for BoNT/A

Human Synaptic Vesicle Glycoprotein 2A (SV2A) interaction partners

  1. Botulinum neurotoxin type A inhibits synaptic vesicle 2 expression in breast cancer cell lines.

  2. SV2A expression in the bladder urothelium increases after BoNT-A injection.

  3. the way LEV analogues may interact with SV2A

  4. agents that act on the conformation of SV2A might hold great potential in the search for new SV2A-based anticonvulsant therapies

  5. The newly identified galactose transport capability of SV2A may have an important role in regulating/modulating synaptic function.

  6. The SV2A/FE65 (show APBB1 Proteins) interaction might play a role in synaptic signal transduction.

  7. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a marked decrease of SV2A paralleling synaptic loss.

  8. High SV2A expression is associated with breast cancer.

  9. This study in the German population provides evidence, at a genetic level, for the involvement of the SV2A gene region in schizophrenia.

  10. Data report a combined modelling and mutagenesis study that successfully identifies another 11 residues in synaptic vesicle protein 2A that appear to be involved in ligand binding.

SV2A Protein Profile

Protein Summary

membrane glycoprotein\; acts as a synaptic vesicle-specific transporter

Gene names and symbols associated with SV2A

  • synaptic vesicle glycoprotein 2A (SV2A)
  • synaptic vesicle glycoprotein 2A (CpipJ_CPIJ017596)
  • synaptic vesicle glycoprotein 2A (sv2a)
  • synaptic vesicle glycoprotein 2 a (Sv2a)
  • synaptic vesicle glycoprotein 2a (Sv2a)
  • AI746429 protein
  • mKIAA0736 protein
  • SV2 protein

Protein level used designations for SV2A

synaptic vesicle glycoprotein 2 , synaptic vesicle glycoprotein 2A , synaptic vesicle glycoprotein 2A-like , calcium regulator SV2A , synaptic vesicle protein 2 , synaptic vesicle protein 2A , synaptic vesicle transmembrane transporter (SV2) RNA , p87

GENE ID SPECIES
457264 Pan troglodytes
6051544 Culex quinquefasciatus
100379721 Xenopus (Silurana) tropicalis
100396256 Callithrix jacchus
100465293 Ailuropoda melanoleuca
100597057 Nomascus leucogenys
100618145 Monodelphis domestica
64051 Mus musculus
117559 Rattus norvegicus
9900 Homo sapiens
101748163 Gallus gallus
280936 Bos taurus
483176 Canis lupus familiaris
100156610 Sus scrofa
100173959 Pongo abelii
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