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a synaptic vesicle protein; conserved between vertebrates and invertebrates. Additionally we are shipping and many more products for this protein.
Showing 10 out of 36 products:
Human Polyclonal SV2C Primary Antibody for ICC, IHC - ABIN1742261
Blum, Przedpelski, Tepp, Johnson, Barbieri: Entry of a recombinant, full-length, atoxic tetanus neurotoxin into Neuro-2a cells. in Infection and immunity 2014
Human Monoclonal SV2C Primary Antibody for ELISA, WB - ABIN524906
Crèvecoeur, Kaminski, Rogister, Foerch, Vandenplas, Neveux, Mazzuferi, Kroonen, Poulet, Martin, Sadzot, Rikir, Klitgaard, Moonen, Deprez: Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis. in Neuropathology and applied neurobiology 2014
Studies indicate that botulinum neurotoxins (BoNTs) in complex with its protein receptor, synaptic vesicle glycoprotein 2 (SV2 (show SV2A Antibodies)) family member C represented a major advance for the detailed molecular understanding of BoNT-host cell receptor interactions.
A genetic variant in SV2C predicted clinically relevant bevacizumab-induced hypertension in two independent, randomised phase III trials.
In classical mesial temporal sclerosis 1A, the expression of SV2 (show SV2A Antibodies) isoforms is altered with a selective increase of SV2C in sprouting mossy fibres.
The fact that multiple SNPs in SV2C may impact response to atypical antipsychotics suggests that further evaluation of SNPs in this gene
high-resolution crystal structure of the BoNT/A receptor-binding domain in complex with the SV2C luminal domain
Results showed that SV2C, a poorly functionally characterized protein is strongly involved in normal operation of the basal ganglia network and could be also involved in system adaptation in basal ganglia pathological conditions.
SV2C protein was expressed in a small subset of brain regions including the olfactory bulb, olfactory tubercle, nucleus accumbens, caudate-putamen, ventral pallidum, globus pallidus, substantia nigra and the ventral tegmental area.
findings show that botulinum neurotoxin (BoNT/A) enters neurons by binding to the synaptic vesicle protein SV2 (show SV2A Antibodies) (isoforms A, B, and C);SV2 (show SV2A Antibodies) acts as the protein receptor for BoNT/A
Botulinum neurotoxin A also interacts with a synaptic vesicle protein, the synaptic vesicle glycoprotein 2C (SV2C), but not with the homologous proteins SV2A (show SV2A Antibodies) and SV2B (show SV2B Antibodies).
a synaptic vesicle protein; conserved between vertebrates and invertebrates
synaptic vesicle glycoprotein 2C
, synaptic vesicle protein 2C