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Synaptojanin 2 Proteins (SYNJ2)

The gene is a member of the inositol-polyphosphate 5-phosphatase family. Additionally we are shipping Synaptojanin 2 Antibodies (58) and Synaptojanin 2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SYNJ2 8871 O15056
SYNJ2 20975 Q9D2G5
Rat SYNJ2 SYNJ2 84018 O55207
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Top Synaptojanin 2 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

SYNJ2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for Synaptojanin 2 (SYNJ2) Interaction Partners

Human Synaptojanin 2 (SYNJ2) interaction partners

  1. Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.

  2. The genetic interactions associated with ILVatrophy rate in this study may be mapping variants inSYNJ2andPI4KAthat interact to decrease synthesisof PIP (show PIP Proteins).

  3. Src (show SRC Proteins)-mediated phosphorylation of SYNJ2 contributes to invadopodia formation.

  4. SYNJ2 is a novel gene in which variation is potentially associated with cognitive abilities.

  5. Single nucleotide polymorphisms in SYNJ2 are associated with personality disorders.

  6. SYNJ2 is a target gene of the BACH1 (show BACH1 Proteins) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 Proteins) 293 cells.

  7. Since Syn 2 is a phosphatidylinositol 4,5-biphosphatase involved in cell growth and rearrangement of actin filaments, the increased Syn 2 expression may correlate with the hairy cell leukemia etiology or the characteristic morphologic alterations.

  8. contributes to the role of Rac1 in cell invasion and migration by regulating the formation of invadopodia and lamellipodia

  9. Identification of inactivating mutations in the JAK1 (show JAK1 Proteins), SYNJ2, and CLPTM1 (show CLPTM1 Proteins) genes in prostate cancer cells

Mouse (Murine) Synaptojanin 2 (SYNJ2) interaction partners

  1. Clustering all known mouse Synj2 transcripts led to uncover a novel subset of transcripts that appears to derive from a region located within intron 7.

  2. These results reveal Synj2 as a critical regulator of hair cell survival that is essential for hair cell maintenance and hearing function.

Synaptojanin 2 (SYNJ2) Protein Profile

Protein Summary

The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Synaptojanin 2 Proteins (SYNJ2)

  • synaptojanin 2 (SYNJ2)
  • synaptojanin 2 (synj2)
  • synaptojanin 2 (Synj2)
  • AI481647 protein
  • INPP5H protein
  • mKIAA0348 protein
  • SJ2 protein
  • SYNJ2 protein

Protein level used designations for Synaptojanin 2 Proteins (SYNJ2)

synaptojanin 2 , inositol phosphate 5'-phosphatase 2 , synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2 , synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2 , synaptojanin-2

484052 Canis lupus familiaris
518435 Bos taurus
100059716 Equus caballus
100074269 Ornithorhynchus anatinus
100216051 Xenopus (Silurana) tropicalis
100355301 Oryctolagus cuniculus
100546337 Meleagris gallopavo
100562404 Anolis carolinensis
8871 Homo sapiens
20975 Mus musculus
84018 Rattus norvegicus
421656 Gallus gallus
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