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Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.
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Cloning and expression analys (show THEG Proteins)is of a similar gene in mouse.
TSEG-2 may participate in the apoptosis of spermatogenic cells and the pathogenesis of cryptorchidism.
SYCE3 is required for male and female fertility.
A novel mouse testis specific (show AIF1 Proteins) gene TSEG-2 was successfully cloned, which could be down-regulated by cryptorchidism-inducible 17-beta estradiol. [TSEG-2]
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility (By similarity).
testis highly expressed gene 2 protein
, testis highly expressed protein 2
, testis-specific expressed protein 2