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Synaptonemal Complex Protein 1 Proteins (SYCP1)

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Additionally we are shipping SYCP1 Antibodies (57) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SYCP1 227292 P58466
SYCP1 6847 Q15431
Rat SYCP1 SYCP1 25276 Q03410
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Top SYCP1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SYCP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Synaptonemal Complex Protein 1 (SYCP1) Interaction Partners

Zebrafish Synaptonemal Complex Protein 1 (SYCP1) interaction partners

  1. Data from male/female transgenic zebrafish suggest proximal promoter fragment coupled to first exon/first intron of sycp1 gene contains information required for cell-specific expression of sycp1 in spermatocytes/spermatids and early primary oocytes.

Mouse (Murine) Synaptonemal Complex Protein 1 (SYCP1) interaction partners

  1. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha (show PKCa Proteins)-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  2. PLK1, but not PLK2-4, phosphorylates central element proteins SYCP1 and TEX12.

  3. SYCP1 and SYCP3 (show SYCP3 Proteins) act at the centromeres to promote the establishment and/or maintenance of centromere pairing and, by doing so, improve the segregation fidelity of mammalian meiotic chromosomes.

  4. Findings suggest that SCP1 (show CRISP1 Proteins) may inhibit the osteoblastic differentiation induced by the BMP-Smad (show SMAD1 Proteins) axis via Runx2 (show RUNX2 Proteins) by suppressing downstream effector(s).

  5. SYCP1 has a coordinating role, and ensures formation of crossovers

  6. The localisation of Syce1 (show SYCE1 Proteins) and Cesc1 (Syce2 (show SYCE2 Proteins)) to the central element depends on recruitment by Sycp1.

Human Synaptonemal Complex Protein 1 (SYCP1) interaction partners

  1. crystal structure of the middle part of the human synaptonemal complex protein 1 coiled-coil domain

  2. SYCP1, cTAGE1, and GTSF1 are expressed in cutaneous T-cell lymphoma, but not in normal skin or benign inflammatory dermatoses.

  3. Cancer-Testis Antigen SCP-1 mRNA is expressed in some nasopharyngeal carcinoma.

  4. an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4 (show CD4 Proteins)+ T cells

SYCP1 Protein Profile

Protein Summary

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Gene names and symbols associated with SYCP1

  • synaptonemal complex protein 1 (sycp1)
  • synaptonemal complex protein 1 (SYCP1)
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (Ctdsp1)
  • synaptonemal complex protein 1 (Sycp1)
  • synaptonemal complex protein ZYP1a (ZYP1a)
  • CT8 protein
  • GIP protein
  • HOM-TES-14 protein
  • Nif3 protein
  • NLIIF protein
  • SCP-1 protein
  • SCP1 protein
  • sycp1 protein
  • syn1 protein
  • T16E15.12 protein
  • T16E15_12 protein
  • ZYP1 protein

Protein level used designations for SYCP1

synaptonemal complex protein 1 , synaptonemal complex protein 1-like , NLI-interacting factor 3 , carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 , golli-interacting protein , nuclear LIM interactor-interacting factor 3 , small C-terminal domain phosphatase 1 , small CTD phosphatase 1 , SCP-1 , cancer/testis antigen 8 , A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes , Meiotic chromosome synaptic protein

GENE ID SPECIES
402797 Danio rerio
457147 Pan troglodytes
772081 Gallus gallus
100049304 Oryzias latipes
100065564 Equus caballus
100415496 Callithrix jacchus
100444416 Pongo abelii
100484897 Ailuropoda melanoleuca
100592558 Nomascus leucogenys
227292 Mus musculus
20957 Mus musculus
6847 Homo sapiens
25276 Rattus norvegicus
606964 Canis lupus familiaris
525413 Bos taurus
101841470 Mesocricetus auratus
838831 Arabidopsis thaliana
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