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SYP encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Additionally we are shipping Synaptophysin Antibodies (309) and Synaptophysin Kits (47) and many more products for this protein.
Showing 4 out of 4 products:
Human Synaptophysin Protein expressed in Wheat germ - ABIN1322008
Caviness, Lue, Beach, Hentz, Adler, Sue, Sadeghi, Driver-Dunckley, Evidente, Sabbagh, Shill, Walker: Parkinson's disease, cortical dysfunction, and alpha-synuclein. in Movement disorders : official journal of the Movement Disorder Society 2011
Show all 2 references for ABIN1322008
In the amygdala, bold monkeys had higher levels of SYP mRNA than reserved monkeys
Synaptophysin decreases with age in the rhesus macaque brain similar to humans.
Study reveals the presence of two selected neuronal markers, MAP-2 and SYP mRNAs and protein expression, in eutopic endometrium and in endometriotic lesions.
Anomalous expression of all intermediate filament proteins and synaptophysin was found in significant subsets of malignant melanoma.
Docosahexaenoic acid-containing phosphatidylcholines and PSD-95 (show DLG4 Proteins) decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease.
This study demonstrated that synaptophysin was significantly lower in Down syndrome with Alzheimer disease compared with Down syndrome alone and similar to sporadic Alzheimer disease.
Patterns of the immunoreactivity with antibodies to SNAP-25 (show SNAP25 Proteins), synapsin-I (show SYN1 Proteins) and synaptophysin are completely appropriate to those of adult's OB on the 38-40 weeks of the prenatal development.
The results of this study suggested that SYP may be primarily associated with ADHD-I and its genetic mechanism may be gender-specific.
The paucity or absence of synaptophysin-positive cells in all three phenotypes of Barrett's mucosa might mirror a sequela of chronic inflammation caused by the particular pathogenic bacteria present in the immediate oesophageal microenvironment.
Data suggest that multi-antibody assay of TTF1 (show NKX2-1 Proteins), Vimentin (show VIM Proteins), p63 (show RPE65 Proteins) CD56 (show NCAM1 Proteins), chromogranin and synaptophysin may be of special value, especially in diagnosing small biopsies.
the author showed that, in cutaneous basal cell carcinoma, the expression of NCAM (show NCAM1 Proteins) and c-KIT was high, PDGFRA (show PDGFRA Proteins) was intermediate, and chromogranin A (show CHGA Proteins) and synaptophysin was relatively low
Depressed patients showed significant decreases in synaptophysin (SYN) and VGLUT1 expression.
The structure of SYP has been determined.
HSV-1-infected neurons also exhibite significantly reduced expression of the presynaptic proteins synapsin-1 and synaptophysin. These effects depended on GSK-3 activation and intraneuronal accumulation of Ab
The balance between synaptophysin and sybII (show VAMP2 Proteins) levels is critical for the correct targeting of sybII (show VAMP2 Proteins) to synaptic vesicles and suggests that alterations in synaptophysin levels might affect the localisation of sybII (show VAMP2 Proteins) and subsequent presynaptic performance.
The high expression of P2X7 receptor (show P2RX7 Proteins) and low expression of synaptophysin in the hippocampus of pups may contribute to the neurotoxicity associated with maternal Pb exposure.
Trimethyltin decreased synaptophysin but not GAP-43 (show GAP43 Proteins) expression in the mouse hippocampus.
These studies suggest that the efficient retrieval of sybII (show VAMP2 Proteins) by synaptophysin may be key to maintaining synaptic health and perturbation of this event may contribute to the pathogenesis underlying neurodevelopmental disorders.
Data indicate that double transgenic (Tg-FDD-Tau) mice showed a significant decrease in synaptophysin levels.
Melatonin can reduce the expression levels of NF-kappaB (show NFKB1 Proteins) p65 (show NFkBP65 Proteins) and synaptophysin in the brain tissue to protect the brain and slow down the aging process.
Glycosylation is dispensable for sorting of synaptotagmin 1 (show SYT1 Proteins) but is critical for targeting of SV2 (show SV2A Proteins) and synaptophysin to recycling synaptic vesicles.
Synaptophysin controls synaptobrevin (sybII (show VAMP2 Proteins))traffic in nerve terminals during synaptic vesicle (SV) endocytosis, an interaction that may act as an adjustable regulator of SV retrieval efficiency.
Cognitive improvement of schizophrenic histopathology may be related to a restoration of synaptophysin and/or Arc (show NOL3 Proteins) levels in the frontal cortex.
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).
, major synaptic vesicle protein P38
, major synaptic vesicle protein p38
, BM89 antigen
, Syp I