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Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes. Additionally we are shipping and many more products for this protein.
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Human Polyclonal SYPL2 Primary Antibody for EIA, IHC (p) - ABIN500857
Nishi, Komazaki, Kurebayashi, Ogawa, Noda, Iino, Takeshima: Abnormal features in skeletal muscle from mice lacking mitsugumin29. in The Journal of cell biology 2000
Show all 4 references for ABIN500857
SYPL2 is a susceptibility gene for morbid obesity.
Mitsugumin (MG)29 is expressed in astrocytes of Alzheimer disease brains associated with senile plaques, but is is not expressed in neurons around lesions.
Ca(2+) transients in skeletal muscle are regulated via interaction between Mg29 and TRPC3.
Data show that slow cumulative calcium entry through store-operated calcium channel (show TRPC1 Antibodies) (SOC (show UBXN11 Antibodies)) is crucial for long-term calcium homeostasis, such that reduced SOC (show UBXN11 Antibodies) activity exaggerates muscle fatigue under conditions of intensive exercise.
MG29 is not involved in the store-operated Ca2 (show CA2 Antibodies)+ entry activation at variance with the previous conclusion with immature muscles
Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes.
, mitsugumin 29
, synaptophysin-like protein 2