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Synaptosomal-Associated Protein, 25kDa Proteins (SNAP25)

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). Additionally we are shipping SNAP25 Antibodies (342) and SNAP25 Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SNAP25 25012 P60881
SNAP25 20614 P60879
SNAP25 6616 P60880
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Top SNAP25 Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$327.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 7 to 9 Days
$364.64
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,031.33
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,504.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,504.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,504.33
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,504.33
Details

SNAP25 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human , ,
,

Top referenced SNAP25 Proteins

  1. Human SNAP25 Protein expressed in Escherichia coli (E. coli) - ABIN2004395 : Chen, Tomchick, Kovrigin, Araç, Machius, Südhof, Rizo: Three-dimensional structure of the complexin/SNARE complex. in Neuron 2002 (PubMed)
    Show all 2 references for ABIN2004395

More Proteins for Synaptosomal-Associated Protein, 25kDa (SNAP25) Interaction Partners

Mouse (Murine) Synaptosomal-Associated Protein, 25kDa (SNAP25) interaction partners

  1. Study showed that SNAP25 is synthesized in the motor nerve endings and that the level of SNAP25 mRNA affects the activity of exocytosis of the neurotransmitter

  2. Data demonstrate a role for SNAP-25 in controlling PSD-95 (show DLG4 Proteins) clustering and open the possibility that genetic reductions of the protein levels may contribute to the pathology through an effect on postsynaptic function and plasticity.

  3. Data suggest that porosome-associated proteins SNAP25, TREK-1 (show KCNK2 Proteins), syntaxin-1A (show STX1A Proteins), and Gai3 exhibit stability and functionality such that isolated proteins can be reconstituted as insulin (show INS Proteins)-secreting porosomes in cell membrane of live cells.

  4. we demonstrate that Syb2 (show VAMP2 Proteins) and SNAP25 mediate the vesicular release of BDNF (show BDNF Proteins) in axons and dendrites of cortical neurons

  5. The extreme C terminus of SNAP25 is a critical region for the GBetaGamma-SNARE (show VTI1B Proteins) interaction.

  6. Data show a significant increase of vesicle-associated membrane protein 2 (VAMP-2 (show VAMP2 Proteins)) mRNA expression, however, the expressions of synaptosome-associated protein of 25 kDa (SNAP-25) and syntaxin 1A (show STX1A Proteins) did not exhibit the changes in hippocampus.

  7. SNAP-25 phosphorylation is regulated in a stress-dependent manner through both central and peripheral mechanisms.

  8. Results indicate that reduction of SNAP-25 expression is associated to generation of epileptiform discharges and cognitive dysfunctions, which can be effectively treated by antiepileptic drugs

  9. direct interaction between TRIM9 (show TRIM9 Proteins) and the Netrin-1 (show NTN1 Proteins) receptor DCC (show DCC Proteins) as well as a Netrin-1 (show NTN1 Proteins)-sensitive interaction between TRIM9 (show TRIM9 Proteins) and the SNARE (show VTI1B Proteins) component SNAP25. The interaction with SNAP25 negatively regulates SNARE (show VTI1B Proteins)-mediated exocytosis and axon

  10. SNAP-25 regulates the organization of the molecular apparatus needed for dendritic spine formation by recruiting and stabilizing p140Cap (show SRCIN1 Proteins).

Human Synaptosomal-Associated Protein, 25kDa (SNAP25) interaction partners

  1. Snap25 rs363050 (G) allele, which results in a reduced expression of Snap25, is associated with altered glycemic parameters in T2DM possibly because of reduced functionality in the exocytotic machinery leading to suboptimal release of insulin (show INS Proteins).

  2. single nucleotide polymorphisms in either the region of NEUROD6 (show NEUROD6 Proteins) or SNAP25 were significantly associated with Alzheimer's Disease, in APOE4+ females and APOE4+ males, respectively.

  3. Data demonstrate a role for SNAP-25 in controlling PSD-95 (show DLG4 Proteins) clustering and open the possibility that genetic reductions of the protein levels may contribute to the pathology through an effect on postsynaptic function and plasticity.

  4. BoNT-A injection, but not Lipotoxin instillation, effectively cleaves SNAP-25 in the suburothelium.

  5. The expression of SNAP-25 within the enteric nervous system and its downregulation in DD suggest an essential role in enteric neurotransmission and as a marker for impaired synaptic plasticity in enteric neuropathies.

  6. Upon glucose stimulation BAG3 (show BAG3 Proteins) is phosphorylated by FAK (show PTK2 Proteins) and dissociates from SNAP-25 allowing the formation of the SNARE (show NAPA Proteins) complex, destabilization of the F-actin network and insulin (show INS Proteins) release.

  7. The SNAP-25 Ddel T/C genotype was more common in fibromyalgia syndrome patients compared to controls, and it related to behavioral symptoms, personality and psychological disorders.

  8. This study demonstrated that SNAP-25 polymorphisms may be associated with Alzheimer's disease and correlate with alterations in categorical fluency and a reduced localized brain activity.

  9. SNARE (show NAPA Proteins) complex genes and their interactions may play a significant role in susceptibility and working memory of ADHD.

  10. Patterns of the immunoreactivity with antibodies to SNAP-25, synapsin-I (show SYN1 Proteins) and synaptophysin (show SYP Proteins) are completely appropriate to those of adult's OB on the 38-40 weeks of the prenatal development.

Cow (Bovine) Synaptosomal-Associated Protein, 25kDa (SNAP25) interaction partners

  1. In individual chromaffin cells, we tracked conformational changes in SNAP25 by total internal reflection fluorescence resonance energy transfer (FRET) microscopy while exocytotic catecholamine release from single vesicles was simultaneously recorded

  2. dynamic experiments using TIRFM revealed that attenuation of cortical F-actin movement clearly diminishes the mobility of SNAP-25 clusters.

  3. Stable syntaxin/SNAP-25 dimers are a central principle of the SNARE (show NAPA Proteins) assembly pathway underlying regulated exocytosis.

  4. microdomains carrying syntaxin1 (show STX1A Proteins)/SNAP-25 and different types of calcium channels act as the sites for physiological granule fusion in "in situ" chromaffin cells

Rhesus Monkey Synaptosomal-Associated Protein, 25kDa (SNAP25) interaction partners

  1. These data demonstrate a differential ability of SNAP-25 homlog to support neuronal function.

Zebrafish Synaptosomal-Associated Protein, 25kDa (SNAP25) interaction partners

  1. data indicate that SNARE (show NAPA Proteins) proteins VAMP-2 (show VAMP2 Proteins) and SNAP-25 play an essential role in daughter blastomere apposition, possibly via the delivery of components that promote the cell-to-cell adhesion required for the successful completion of cytokinesis

SNAP25 Protein Profile

Protein Summary

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Gene names and symbols associated with SNAP25

  • synaptosomal-associated protein, 25kDa (snap25)
  • synaptosomal-associated protein 25 (BACOIKO003_07)
  • synaptosomal-associated protein 25 (Tsp_10811)
  • SNAP25a (snap25)
  • synaptosomal-associated protein 25 (Snap25)
  • synaptosomal-associated protein 25 (LOC100340057)
  • synaptosomal-associated protein, 25kDa (SNAP25)
  • synaptosomal-associated protein, 25kDa (Snap25)
  • zgc:101731 (zgc:101731)
  • bA416N4.2 protein
  • Bdr protein
  • dJ1068F16.2 protein
  • fj55h11 protein
  • RIC-4 protein
  • RIC4 protein
  • SEC9 protein
  • SNAP protein
  • SNAP-25 protein
  • SNAP-25a protein
  • SNAP-25B protein
  • snap25 protein
  • sp protein
  • wu:fj55h11 protein

Protein level used designations for SNAP25

synaptosomal-associated protein 25 , SNAP-25 , SUP , super protein , synaptosomal-associated 25 kDa protein , synaptosomal-associated protein, 25 kDa , GENA 70 , blind drunk , resistance to inhibitors of cholinesterase 4 homolog , synaptosomal associated protein-25 , synaptosomal-associated protein 25 isoform SNAP25B , synaptosomal-associated 25kD protein

GENE ID SPECIES
380202 Xenopus laevis
549255 Xenopus (Silurana) tropicalis
6166920 Oikopleura dioica
10897177 Trichinella spiralis
399171 Xenopus laevis
25012 Rattus norvegicus
20614 Mus musculus
100340057 Oryctolagus cuniculus
6616 Homo sapiens
540853 Bos taurus
396444 Gallus gallus
477158 Canis lupus familiaris
100724783 Cavia porcellus
101092511 Felis catus
574204 Macaca mulatta
100174149 Pongo abelii
458096 Pan troglodytes
447892 Danio rerio
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