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Synaptotagmin I (SYT1) ELISA Kits

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Additionally we are shipping SYT1 Antibodies (221) and SYT1 Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SYT1 74498 Q91X51
Anti-Human SYT1 SYT1 6857 P21579
Anti-Rat SYT1 SYT1 25716 P21707
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Top SYT1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.09 ng/mL 0.16-10 ng/mL Diagramm of the ELISA kit to detect Mouse SYT1with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Log in to see 8 to 9 Days
$680.63
Details

More ELISA Kits for SYT1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Synaptotagmin I (SYT1) interaction partners

  1. tethering of Syt1 to synaptic vesicles in vivo is a prerequisite for its role in facilitating fast synchronous synaptic vesicle release and suppressing asynchronous and spontaneous fusion

  2. synaptic transmission can be regulated by Syt1 multimerization and that both C2 domains of Syt1 are uniquely required for modulating Ca(2 (show CA2 ELISA Kits)+)-independent spontaneous fusion and Ca(2 (show CA2 ELISA Kits)+)-dependent synchronous release.

  3. effect of APP (show APP ELISA Kits) gene on synaptotagmin 1 mRNA level

  4. The major function of Ca2+ binding to synaptotagmin's C2A domain is to neutralize the negative charge of the pocket, thereby unleashing the fusion-stimulating activity of synaptotagmin.

  5. this study provided direct support for the hypothesis that plasma membrane penetration, specifically by the C(2)B domain of synaptotagmin, is the critical effector interaction for coupling Ca(2 (show CA2 ELISA Kits)+) binding with vesicle fusion

  6. Results suggest that the tandem C2 domains of Syt 1 play independent roles in neurotransmission.

  7. The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo

  8. Synaptotagmins I and IV promote transmitter release independently of Ca(2 (show CA2 ELISA Kits)+) binding in the C(2)A domain

  9. Data show that synaptotagmin I is required for a post-docking step during vesicle fusion but does not function to stabilize the docked vesicle state.

  10. These results indicate that synaptotagmin is the major Ca(2 (show CA2 ELISA Kits)+) sensor for evoked release and functions to trigger synchronous fusion in response to Ca(2 (show CA2 ELISA Kits)+), while suppressing asynchronous release.

Mouse (Murine) Synaptotagmin I (SYT1) interaction partners

  1. data show that hepatic Syt1 expression is influenced by diet and hormonal milieu

  2. different structural states of syt (show SS18 ELISA Kits) underlie the control of distinct forms of synaptic transmission.

  3. The interaction of Dvl1 (show DVL1 ELISA Kits) with Syt-1, which is regulated by Wnts, modulates neurotransmitter release.

  4. Data (including data from studies in knockout mice) suggest that loss of both Syt1/Syt7 (show SYT7 ELISA Kits) decreases capacity of readily-releasable pool (RRP (show RRBP1 ELISA Kits)) of Ca2 (show CA2 ELISA Kits)+ in synaptic vesicles without altering rate of priming into RRP (show RRBP1 ELISA Kits); Syt1/Syt7 (show SYT7 ELISA Kits) functions appear redundant.

  5. Syt-1 regulates Abeta (show APP ELISA Kits) levels in mouse neurons. Knockdown of endogenous Syt-1 in mouse primary neurons led to a significant reduction in both Abeta40 and Abeta42 generation.

  6. Increased expression of Syt1 in neural stem cells is essential for neurogenesis progression.

  7. This study provides new insights in how the two opposite sides of the C2B domain of Synaptotagmin-1 participate in secretory vesicle fusion, and in more upstream steps, especially vesicle docking.

  8. atomic-resolution crystal structures of Ca(2 (show CA2 ELISA Kits)+)- and Mg(2 (show MCOLN1 ELISA Kits)+)-bound complexes between synaptotagmin-1 and the neuronal SNARE (show VTI1B ELISA Kits) complex

  9. the Ca(2 (show CA2 ELISA Kits)+) dependence of the interaction between PRIP (show NCOA6 ELISA Kits)-C2 and Syt1-C2A was attributed to Ca(2 (show CA2 ELISA Kits)+) binding with Syt1-C2A, but not PRIP (show NCOA6 ELISA Kits)-C2, using a series of mutants prepared from both C2 domains.

  10. Tissue-specific splicing, posttranslational modification and the variation in expression might suggest a different requirement of SYT1 for the specific function in each organ.

Human Synaptotagmin I (SYT1) interaction partners

  1. These findings identify Syt1 as a novel Ca(2 (show CA2 ELISA Kits)+)-sensitive PS1 (show PSEN1 ELISA Kits) modulator that could regulate synaptic ABETA (show APP ELISA Kits), opening avenues for novel and selective synapse targeting therapeutic strategies.

  2. One-Step reverse transcriptase real time PCR for the detection SYT-SSX transcript is feasible as an aid in confirming the diagnosis of synovial sarcoma.

  3. membrane tethering by E-Syt1 (ER to PM) and by synaptotagmin (secretory vesicles to PM) undergo a similar regulation by plasma membrane lipids and cytosolic Ca(2 (show CA2 ELISA Kits)+).

  4. A dominant negative de novo SYT1 missense variant(I368T)altered the kinetics of synaptic vesicle endocytosis and caused an early onset dyskinetic movement disorder, severe motor delay, and profound cognitive impairment.

  5. Data suggest that calcium-dependent phosphatidylinositol 4,5-diphosphate- (PI(4,5)P2-) binding proteins (such as SYT1, PRKCA (show PKCa ELISA Kits) [protein kinase C alpha (show PKCa ELISA Kits)], and ANXA2 (show ANXA2 ELISA Kits) [annexin A2 (show ANXA2 ELISA Kits)]) interactions with membrane microdomains are tightly regulated. [REVIEW]

  6. Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 (show DDR2 ELISA Kits) rearrangements.

  7. Hydrophobic interactions play a key role in Syt1 binding botulinum neurotoxin DC.

  8. Structural insights into the Ca2 (show CA2 ELISA Kits)+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A (show RPH3A ELISA Kits) and synaptotagmin 1.

  9. synaptotagmin-1 is involved in a rapid vesicular Ca(2 (show CA2 ELISA Kits)) sequestration through a Ca(2 (show CA2 ELISA Kits))/H antiport

  10. PRIP (show PLCL1 ELISA Kits) inhibits regulated exocytosis through the interaction of its C2 domain with syntaxin 1 (show STX1A ELISA Kits) and SNAP-25 (show SNAP25 ELISA Kits), potentially competing with accessory proteins such as synaptotagmin I and by directly inhibiting trans-SNARE (show NAPA ELISA Kits) complex formation

Cow (Bovine) Synaptotagmin I (SYT1) interaction partners

SYT1 Antigen Profile

Antigen Summary

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001

Gene names and symbols associated with Synaptotagmin I (SYT1) ELISA Kits

  • Synaptotagmin 1 (Syt1) antibody
  • synaptotagmin I (Syti) antibody
  • synaptotagmin I (SYT1) antibody
  • synaptotagmin-1 (Tsp_06980) antibody
  • synaptotagmin-1 (Tsp_08220) antibody
  • synaptotagmin 1 (syt1) antibody
  • DKFZP459P193 protein (DKFZP459P193) antibody
  • golgi reassembly stacking protein 1 (Gorasp1) antibody
  • synaptotagmin I (Syt1) antibody
  • synaptotagmin VIII (syt8) antibody
  • synaptotagmin VIII (SYT8) antibody
  • synaptotagmin-like 1 (SYTL1) antibody
  • synaptotagmin, p65 (LOC100533340) antibody
  • 5430411C10Rik antibody
  • AW124717 antibody
  • CG3139 antibody
  • D. Syt I antibody
  • DKFZP459P193 antibody
  • Dmel\\CG3139 antibody
  • Droso1 antibody
  • DSypt antibody
  • dSYT antibody
  • dsyt1 antibody
  • Dsyt2 antibody
  • dsytI antibody
  • G630098F17Rik antibody
  • GB20036 antibody
  • GOLPH5 antibody
  • GRASP65 antibody
  • l(2)23AB1 antibody
  • l(2)23Ba antibody
  • l(2)k05909 antibody
  • p65 antibody
  • SVP65 antibody
  • syt antibody
  • syt-1 antibody
  • syt 1 antibody
  • syt1 antibody
  • syt I antibody
  • Syti antibody

Protein level used designations for Synaptotagmin I (SYT1) ELISA Kits

CG3139-PA , CG3139-PB , CG3139-PC , CG3139-PE , CG3139-PF , CG3139-PG , Synaptotagmin-1 , Synaptotagmin-I , Synaptotagmin1 , SynaptotagminI , Syt1-PA , Syt1-PB , Syt1-PC , Syt1-PE , Syt1-PF , Syt1-PG , synaptoptagmin 1 , synaptotagmin , synaptotagmin 1 , synaptotagmin I , synaptotagmin-1 , DKFZP459P193 protein , Synaptotagmin I , Golgi reassembly-stacking protein 1 , golgi peripheral membrane protein p65 , golgi reassembly-stacking protein of 65 kDa , sytI , p65 , synaptotagmin p65 , synaptotagmin 8 , synaptotagmin I VQ/C2B-beta

GENE ID SPECIES
33473 Drosophila melanogaster
408613 Apis mellifera
657877 Tribolium castaneum
751605 Taeniopygia guttata
10903271 Trichinella spiralis
10906784 Trichinella spiralis
100037879 Xenopus (Silurana) tropicalis
100189845 Pongo abelii
74498 Mus musculus
6857 Homo sapiens
20979 Mus musculus
25716 Rattus norvegicus
482579 Canis lupus familiaris
281511 Bos taurus
396083 Gallus gallus
100513599 Sus scrofa
100174463 Pongo abelii
695390 Macaca mulatta
570237 Danio rerio
423095 Gallus gallus
487346 Canis lupus familiaris
100511935 Sus scrofa
527641 Bos taurus
100533340 Aplysia californica
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