You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Synaptotagmin I (SYT1) Antibodies

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Additionally we are shipping SYT1 Proteins (21) and SYT1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SYT1 74498 Q91X51
SYT1 6857 P21579
SYT1 25716 P21707
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top anti-SYT1 Antibodies at

Showing 10 out of 230 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Mouse Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF 0.1 mL Log in to see 6 to 8 Days
Rat Mouse Un-conjugated IF, IP, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF, WB 0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF, WB 0.1 mL Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated DB, IHC (fro), WB 0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Human Goat Un-conjugated IHC, ELISA, WB EB08253 (1µg/ml) staining of Human Hippocampus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using SYT1 mouse mAb against truncated Trx-SYT1 recombinant protein (1) . 100 μL Log in to see 3 to 4 Days

SYT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , , ,
, , , ,

, , , , , , , , , , ,
Human , , , ,
, , ,
, , , , , , , , , , , , , ,
Rat (Rattus) , , , ,
, , ,
, , , , , , , , , , ,

Top referenced anti-SYT1 Antibodies

  1. Rat (Rattus) Monoclonal SYT1 Primary Antibody for IF, IP - ABIN1109184 : Suzuki, Hide, Ido, Kohsaka, Inoue, Nakata: Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Show all 17 references for ABIN1109184

  2. Cow (Bovine) Polyclonal SYT1 Primary Antibody for DB, IHC (fro) - ABIN372724 : Fernández-Chacón, Königstorfer, Gerber, García, Matos, Stevens, Brose, Rizo, Rosenmund, Südhof: Synaptotagmin I functions as a calcium regulator of release probability. in Nature 2001 (PubMed)
    Show all 5 references for ABIN372724

  3. Human Polyclonal SYT1 Primary Antibody for IF, WB - ABIN319341 : Cnops, Hu, Burnat, Arckens: Influence of binocular competition on the expression profiles of CRMP2, CRMP4, Dyn I, and Syt I in developing cat visual cortex. in Cerebral cortex (New York, N.Y. : 1991) 2008 (PubMed)
    Show all 3 references for ABIN319341

  4. Human Polyclonal SYT1 Primary Antibody for IF, WB - ABIN401634 : Lynch, Gerona, Larsen, Marcia, Mitchell, Martin: Synaptotagmin C2A loop 2 mediates Ca2+-dependent SNARE interactions essential for Ca2+-triggered vesicle exocytosis. in Molecular biology of the cell 2007 (PubMed)
    Show all 3 references for ABIN401634

  5. Cow (Bovine) Polyclonal SYT1 Primary Antibody for WB - ABIN372723 : Littleton, Bellen: Synaptotagmin controls and modulates synaptic-vesicle fusion in a Ca(2+)-dependent manner. in Trends in neurosciences 1995 (PubMed)
    Show all 2 references for ABIN372723

  6. Rat (Rattus) Monoclonal SYT1 Primary Antibody for WB - ABIN1449190 : Watson, Schinzel, Palm, Johnson: The crystal structure of Escherichia coli maltodextrin phosphorylase provides an explanation for the activity without control in this basic archetype of a phosphorylase. in The EMBO journal 1997 (PubMed)
    Show all 2 references for ABIN1449190

  7. Human Polyclonal SYT1 Primary Antibody for IF - ABIN401602 : Gustavsson, Lao, Maximov, Chuang, Kostromina, Repa, Li, Radda, Südhof, Han: Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against SYT1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Synaptotagmin I (SYT1) interaction partners

  1. tethering of Syt1 to synaptic vesicles in vivo is a prerequisite for its role in facilitating fast synchronous synaptic vesicle release and suppressing asynchronous and spontaneous fusion

  2. synaptic transmission can be regulated by Syt1 multimerization and that both C2 domains of Syt1 are uniquely required for modulating Ca(2 (show CA2 Antibodies)+)-independent spontaneous fusion and Ca(2 (show CA2 Antibodies)+)-dependent synchronous release.

  3. effect of APP (show APP Antibodies) gene on synaptotagmin 1 mRNA level

  4. The major function of Ca2+ binding to synaptotagmin's C2A domain is to neutralize the negative charge of the pocket, thereby unleashing the fusion-stimulating activity of synaptotagmin.

  5. this study provided direct support for the hypothesis that plasma membrane penetration, specifically by the C(2)B domain of synaptotagmin, is the critical effector interaction for coupling Ca(2 (show CA2 Antibodies)+) binding with vesicle fusion

  6. Results suggest that the tandem C2 domains of Syt 1 play independent roles in neurotransmission.

  7. The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo

  8. Synaptotagmins I and IV promote transmitter release independently of Ca(2 (show CA2 Antibodies)+) binding in the C(2)A domain

  9. Data show that synaptotagmin I is required for a post-docking step during vesicle fusion but does not function to stabilize the docked vesicle state.

  10. These results indicate that synaptotagmin is the major Ca(2 (show CA2 Antibodies)+) sensor for evoked release and functions to trigger synchronous fusion in response to Ca(2 (show CA2 Antibodies)+), while suppressing asynchronous release.

Mouse (Murine) Synaptotagmin I (SYT1) interaction partners

  1. GRASP65 (show GORASP1 Antibodies) phosphorylation may have a critical role in inducing cell death.

  2. We conclude that synaptotagmin-1 phosphorylation is an essential step in PKC (show PKC Antibodies)-dependent potentiation of synaptic transmission, acting downstream of the two other essential DAG/PKC (show PKC Antibodies) substrates, Munc13-1 (show UNC13A Antibodies) and Munc18-1 (show STXBP1 Antibodies).

  3. data show that hepatic Syt1 expression is influenced by diet and hormonal milieu

  4. different structural states of syt (show SS18 Antibodies) underlie the control of distinct forms of synaptic transmission.

  5. The interaction of Dvl1 (show DVL1 Antibodies) with Syt-1, which is regulated by Wnts, modulates neurotransmitter release.

  6. Data (including data from studies in knockout mice) suggest that loss of both Syt1/Syt7 (show SYT7 Antibodies) decreases capacity of readily-releasable pool (RRP (show RRBP1 Antibodies)) of Ca2 (show CA2 Antibodies)+ in synaptic vesicles without altering rate of priming into RRP (show RRBP1 Antibodies); Syt1/Syt7 (show SYT7 Antibodies) functions appear redundant.

  7. Syt-1 regulates Abeta (show APP Antibodies) levels in mouse neurons. Knockdown of endogenous Syt-1 in mouse primary neurons led to a significant reduction in both Abeta40 and Abeta42 generation.

  8. Increased expression of Syt1 in neural stem cells is essential for neurogenesis progression.

  9. This study provides new insights in how the two opposite sides of the C2B domain of Synaptotagmin-1 participate in secretory vesicle fusion, and in more upstream steps, especially vesicle docking.

  10. atomic-resolution crystal structures of Ca(2 (show CA2 Antibodies)+)- and Mg(2 (show MCOLN1 Antibodies)+)-bound complexes between synaptotagmin-1 and the neuronal SNARE (show VTI1B Antibodies) complex

Human Synaptotagmin I (SYT1) interaction partners

  1. These findings identify Syt1 as a novel Ca(2 (show CA2 Antibodies)+)-sensitive PS1 (show PSEN1 Antibodies) modulator that could regulate synaptic ABETA (show APP Antibodies), opening avenues for novel and selective synapse targeting therapeutic strategies.

  2. One-Step reverse transcriptase real time PCR for the detection SYT (show SS18 Antibodies)-SSX (show SSX2 Antibodies) transcript is feasible as an aid in confirming the diagnosis of synovial sarcoma.

  3. membrane tethering by E-Syt1 (show ESYT1 Antibodies) (ER to PM) and by synaptotagmin (secretory vesicles to PM) undergo a similar regulation by plasma membrane lipids and cytosolic Ca(2 (show CA2 Antibodies)+).

  4. A dominant negative de novo SYT1 missense variant(I368T)altered the kinetics of synaptic vesicle endocytosis and caused an early onset dyskinetic movement disorder, severe motor delay, and profound cognitive impairment.

  5. Data suggest that calcium-dependent phosphatidylinositol 4,5-diphosphate- (PI(4,5)P2-) binding proteins (such as SYT1, PRKCA (show PKCa Antibodies) [protein kinase C alpha (show PKCa Antibodies)], and ANXA2 (show ANXA2 Antibodies) [annexin A2 (show ANXA2 Antibodies)]) interactions with membrane microdomains are tightly regulated. [REVIEW]

  6. Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 (show DDR2 Antibodies) rearrangements.

  7. Hydrophobic interactions play a key role in Syt1 binding botulinum neurotoxin DC.

  8. Structural insights into the Ca2 (show CA2 Antibodies)+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A (show RPH3A Antibodies) and synaptotagmin 1.

  9. synaptotagmin-1 is involved in a rapid vesicular Ca(2 (show CA2 Antibodies)) sequestration through a Ca(2 (show CA2 Antibodies))/H antiport

  10. PRIP (show PLCL1 Antibodies) inhibits regulated exocytosis through the interaction of its C2 domain with syntaxin 1 (show STX1A Antibodies) and SNAP-25 (show SNAP25 Antibodies), potentially competing with accessory proteins such as synaptotagmin I and by directly inhibiting trans-SNARE (show NAPA Antibodies) complex formation

Cow (Bovine) Synaptotagmin I (SYT1) interaction partners

SYT1 Antigen Profile

Protein Summary

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001

Gene names and symbols associated with anti-Synaptotagmin I (SYT1) Antibodies

  • Synaptotagmin 1 (Syt1) antibody
  • synaptotagmin I (Syti) antibody
  • synaptotagmin I (SYT1) antibody
  • synaptotagmin-1 (Tsp_06980) antibody
  • synaptotagmin-1 (Tsp_08220) antibody
  • synaptotagmin 1 (syt1) antibody
  • DKFZP459P193 protein (DKFZP459P193) antibody
  • golgi reassembly stacking protein 1 (Gorasp1) antibody
  • synaptotagmin I (Syt1) antibody
  • synaptotagmin VIII (syt8) antibody
  • synaptotagmin VIII (SYT8) antibody
  • synaptotagmin-like 1 (SYTL1) antibody
  • synaptotagmin, p65 (LOC100533340) antibody
  • 5430411C10Rik antibody
  • AW124717 antibody
  • CG3139 antibody
  • D. Syt I antibody
  • DKFZP459P193 antibody
  • Dmel\\CG3139 antibody
  • Droso1 antibody
  • DSypt antibody
  • dSYT antibody
  • dsyt1 antibody
  • Dsyt2 antibody
  • dsytI antibody
  • G630098F17Rik antibody
  • GB20036 antibody
  • GOLPH5 antibody
  • GRASP65 antibody
  • l(2)23AB1 antibody
  • l(2)23Ba antibody
  • l(2)k05909 antibody
  • p65 antibody
  • SVP65 antibody
  • syt antibody
  • syt-1 antibody
  • syt 1 antibody
  • syt1 antibody
  • syt I antibody
  • Syti antibody

Protein level used designations for anti-Synaptotagmin I (SYT1) Antibodies

CG3139-PA , CG3139-PB , CG3139-PC , CG3139-PE , CG3139-PF , CG3139-PG , Synaptotagmin-1 , Synaptotagmin-I , Synaptotagmin1 , SynaptotagminI , Syt1-PA , Syt1-PB , Syt1-PC , Syt1-PE , Syt1-PF , Syt1-PG , synaptoptagmin 1 , synaptotagmin , synaptotagmin 1 , synaptotagmin I , synaptotagmin-1 , DKFZP459P193 protein , Synaptotagmin I , Golgi reassembly-stacking protein 1 , golgi peripheral membrane protein p65 , golgi reassembly-stacking protein of 65 kDa , sytI , p65 , synaptotagmin p65 , synaptotagmin 8 , synaptotagmin I VQ/C2B-beta

33473 Drosophila melanogaster
408613 Apis mellifera
657877 Tribolium castaneum
751605 Taeniopygia guttata
10903271 Trichinella spiralis
10906784 Trichinella spiralis
100037879 Xenopus (Silurana) tropicalis
100189845 Pongo abelii
74498 Mus musculus
6857 Homo sapiens
20979 Mus musculus
25716 Rattus norvegicus
482579 Canis lupus familiaris
281511 Bos taurus
396083 Gallus gallus
100513599 Sus scrofa
100174463 Pongo abelii
695390 Macaca mulatta
570237 Danio rerio
423095 Gallus gallus
487346 Canis lupus familiaris
100511935 Sus scrofa
527641 Bos taurus
100533340 Aplysia californica
Selected quality suppliers for anti-SYT1 (SYT1) Antibodies
Did you look for something else?