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The protein encoded by SYT6 belongs to the synaptotagmin family. Additionally we are shipping Synaptotagmin VI Antibodies (99) and many more products for this protein.
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synaptotagmin must be dephosphorylated at a specific window of time and phosphorylated synaptotagmin has an active role at early stages of the acrosomal exocytosis.
Acrosomal exocytosis is regulated through the PKC (show PRRT2 Proteins)-mediated phosphorylation of conserved threonines in the polybasic regions of synaptotagmin VI.
SYT6 is hypermethylated in renal cell carcinoma (show MOK Proteins).
The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene.
, synaptotagmin 6