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SYT12 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Additionally we are shipping Synaptotagmin XII Proteins (7) and many more products for this protein.
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Mouse (Murine) Polyclonal SYT12 Primary Antibody for IHC, WB - ABIN350912
Carninci, Kasukawa, Katayama, Gough, Frith, Maeda, Oyama, Ravasi, Lenhard, Wells, Kodzius, Shimokawa, Bajic, Brenner, Batalov, Forrest, Zavolan, Davis, Wilming, Aidinis, Allen, Ambesi-Impiombato et al.: The transcriptional landscape of the mammalian genome. ... in Science (New York, N.Y.) 2005
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Studies of the orthologous gene in rat have shown that spontaneous synaptic-vesicle exocytosis is selectively modulated by synaptotagmin 12 (show SYT11 Antibodies).
Synaptotagmin-12 is essential for cyclic AMP-dependent protein kinase presynaptic long term potentiation at mossy-fiber synapses.
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
, synaptotagmin 12
, synaptotagmin-related gene 1 protein