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Syncoilin Proteins (Sync)

Sync encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. Additionally we are shipping Syncoilin Antibodies (20) and Syncoilin Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Sync 68828 Q9EPM5
Rat Sync Sync 362606  
Sync 81493 Q9H7C4
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Top Syncoilin Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Sf-9 Cells Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$460.85
Details

Sync Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Syncoilin (Sync) Interaction Partners

Mouse (Murine) Syncoilin (Sync) interaction partners

  1. in the liver, syncoilin is predominantly expressed by activated Hepatic stellate cells and displays very low-expression levels in other liver cell types, making it a good marker of activated Hepatic stellate cells.

  2. A neuronal analysis of the syn (show PRPH Proteins)coilin-null mouse (Sync(-/-)) revealed a reduced ability in accelerating treadmill and rotarod tests.

  3. The data show that absence of alpha-dystrobrevin (show DTNA Proteins) or desmin (show DES Proteins) leads to dynamic changes in syncoilin that may compensate for, or participate in, different muscle myopathies.

  4. Syncoilin may play a supportive role for desmin (show DES Proteins) in the efficient coupling of mechanical stress between the myofibril and muscle fiber exterior.

  5. A second viable syncoilin knockout model and highlights the importance of further investigations to determine the role of syncoilin in skeletal muscle.

  6. Despite lacking an apparent structural role in striated (show NSDHL Proteins) muscle, the three syncoilin isoforms are differentially and strongly upregulated during muscle regeneration and atrophy in C57BL/6 mice, possibly suggesting an atypical role for syncoilin in muscle.

Human Syncoilin (Sync) interaction partners

  1. Syncoilin modulates peripherin (show PRPH Proteins) filament network formation.

  2. The differences in human syncoilin and beta-synemin (show SYNM Proteins) mRNA ratios between Duchenne muscular dystrophy (show DMD Proteins) and normal muscles were not statistically significant

  3. the result of this study raise the possibility that mutations in the gene encoding for syncoilin may underlie some forms of muscle disease.

Syncoilin (Sync) Protein Profile

Protein Summary

This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Syncoilin Proteins (Sync)

  • syncoilin (Sync)
  • syncoilin, intermediate filament protein (Sync)
  • syncoilin, intermediate filament protein (SYNC)
  • 1110057H03Rik protein
  • SNIP4 protein
  • SYNC1 protein
  • SYNCOILIN protein

Protein level used designations for Syncoilin Proteins (Sync)

syncoilin intermediate filament 1 , syncoilin-1 , intermediate filament protein syncoilin , syncoilin , syncoilin, intermediate filament 1

GENE ID SPECIES
68828 Mus musculus
362606 Rattus norvegicus
81493 Homo sapiens
419664 Gallus gallus
487303 Canis lupus familiaris
100620771 Sus scrofa
618122 Bos taurus
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