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SYNRG encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. Additionally we are shipping SYNRG Kits (9) and SYNRG Proteins (3) and many more products for this protein.
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the aftiphilin (show AFTPH Antibodies)/p200 (show CUX1 Antibodies)/gamma-synergin complex facilitates AP-1 (show FOSB Antibodies) function
AP-3 and AP-1 (show FOSB Antibodies) function in partially redundant pathways to transfer tyrosinase (show TYR Antibodies) from distinct endosomal subdomains to melanosomes
Data show that by recruiting aftiphilin (show AFTPH Antibodies)/gamma-synergin in addition to clathrin, AP-1 (show FOSB Antibodies) coordinates formation of Weibel-Palade bodies with their acquisition of a regulated secretory phenotype.
This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene.
, AP1 gamma subunit binding protein 1
, synergin gamma
, AP1 subunit gamma-binding protein 1
, adaptor-related protein complex 1 gamma subunit-binding protein 1