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Synovial Sarcoma Translocation, Chromosome 18 Proteins (SS18)

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Additionally we are shipping Synovial Sarcoma Translocation, Chromosome 18 Antibodies (27) and Synovial Sarcoma Translocation, Chromosome 18 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SS18 6857 P21579
SS18 268996 Q62280
Rat SS18 SS18 361295  
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Top Synovial Sarcoma Translocation, Chromosome 18 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,160.67
Details

SS18 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Synovial Sarcoma Translocation, Chromosome 18 (SS18) Interaction Partners

Human Synovial Sarcoma Translocation, Chromosome 18 (SS18) interaction partners

  1. These findings identify Syt1 (show SYT1 Proteins) as a novel Ca(2 (show CA2 Proteins)+)-sensitive PS1 (show PSEN1 Proteins) modulator that could regulate synaptic ABETA (show APP Proteins), opening avenues for novel and selective synapse targeting therapeutic strategies.

  2. One-Step reverse transcriptase real time PCR for the detection SYT-SSX (show SSX2 Proteins) transcript is feasible as an aid in confirming the diagnosis of synovial sarcoma.

  3. membrane tethering by E-Syt1 (ER to PM) and by synaptotagmin (secretory vesicles to PM) undergo a similar regulation by plasma membrane lipids and cytosolic Ca(2 (show CA2 Proteins)+).

  4. a rare variant of the SS18-SSX1 (show SSX1 Proteins) fusion transcript, which could not be identified by routine procedures for genetic diagnosis, was detected. In addition, 8 missense mutations of cancer-related genes were confirmed

  5. A dominant negative de novo SYT1 (show SYT1 Proteins) missense variant(I368T)altered the kinetics of synaptic vesicle endocytosis and caused an early onset dyskinetic movement disorder, severe motor delay, and profound cognitive impairment.

  6. Data suggest that calcium-dependent phosphatidylinositol 4,5-diphosphate- (PI(4,5)P2-) binding proteins (such as SYT1 (show SYT1 Proteins), PRKCA (show PKCa Proteins) [protein kinase C alpha (show PKCa Proteins)], and ANXA2 (show ANXA2 Proteins) [annexin A2 (show ANXA2 Proteins)]) interactions with membrane microdomains are tightly regulated. [REVIEW]

  7. Case Report: bronchial biphasic synovial sarcoma with SS18 gene rearrangement.

  8. SS18-SSX (show SSX2 Proteins)-induced Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling appears to be of crucial biological importance in synovial sarcoma tumorigenesis and progression.

  9. Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 (show SYT1 Proteins) and DDR2 (show DDR2 Proteins) rearrangements.

  10. SYT gene split is associated with Synovial sarcoma.

Mouse (Murine) Synovial Sarcoma Translocation, Chromosome 18 (SS18) interaction partners

  1. disruption of the Ss18 gene results in a recessive embryonic lethal phenotype, due to placental failure caused by impairment of placental vascularization and/or chorio-allantoic fusion

  2. Syt may contribute to the signaling pathway important for various cellular functions in vivo and in vitro, and we propose that Syt-deficient MEFs would be a powerful means to understand the biological roles of SYT in vitro.

Synovial Sarcoma Translocation, Chromosome 18 (SS18) Protein Profile

Protein Summary

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001

Gene names and symbols associated with SS18

  • synaptotagmin I (SYT1)
  • synovial sarcoma translocation, chromosome 18 (SS18)
  • synovial sarcoma translocation, Chromosome 18 (Ss18)
  • D130059H17 protein
  • P65 protein
  • Ssxt protein
  • SVP65 protein
  • Syt protein

Protein level used designations for SS18

synaptotagmin 1 , synaptotagmin-1 , sytI , protein SSXT , synovial sarcoma translocated to X chromosome protein , synovial sarcoma, translocated to X chromosome , synovial sarcoma associated SS18-beta , synovial sarcoma associated SS18-delta , synovial sarcoma associated SS18-gamma , synovial sarcoma-associated Ss18-alpha

GENE ID SPECIES
6857 Homo sapiens
6760 Homo sapiens
268996 Mus musculus
361295 Rattus norvegicus
100173694 Pongo abelii
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