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Implicated in vesicle trafficking to lysosomes. Additionally we are shipping Syntaxin 17 Antibodies (29) and Syntaxin 17 Proteins (5) and many more products for this protein.
Homotypic fusion and vacuole protein sorting complex colocalizes and interacts with Syntaxin 17, suggesting their association is critical during tethering and fusion of autophagosomes with lysosomes.
Syntaxin17 is recruited to the outer membrane of autophagosomes to mediate fusion through its interactions with ubisnap (SNAP-29 (show SNAP29 ELISA Kits)) and VAMP7 (show VAMP7 ELISA Kits) in Drosophila melanogaster
A 4.6 kb duplication in Syntaxin 17, associated with the Grey phenotype in horses, does not only predispose to melanoma development, but that a copy number expansion of the duplication may be a driving force for melanoma development.
In transgenic zebrafish, a construct with 2 copies of a 4.6-kb intronic duplication is a strong enhancer in neural crest cells but a single copy is a weak enhancer. It contains 2 MITF (show MITF ELISA Kits) binding sites.
Both STX17 and the neighboring NR4A3 (show NR4A3 ELISA Kits) gene are overexpressed in melanomas from Gray horses.
the homotypic fusion and protein sorting-tethering complex promotes autophagosome-lysosome fusion through interaction with STX17
Study identifies syntaxin 17 (Stx17) as the autophagosomal SNARE (show NAPA ELISA Kits) required for fusion with the endosome/lysosome.
The syntaxin 17 is essential for maintaining the architecture of ERGIC and Golgi.
Common variants in the STX17 gene region do not play a key role in the pathogenesis of human melanoma.
Study identifies syntaxin 17 (Stx17) as the autophagosomal SNARE (show VTI1B ELISA Kits) required for fusion with the endosome/lysosome.
Implicated in vesicle trafficking to lysosomes. Could be involved in processes related to cell division (By similarity).
, syntaxin 17