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Syntaxin 4 Proteins (STX4)

Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity).. Additionally we are shipping Syntaxin 4 Antibodies (74) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STX4 6810 Q12846
Rat STX4 STX4 81803 Q08850
STX4 20909 P70452
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Top Syntaxin 4 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

STX4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

Top referenced Syntaxin 4 Proteins

  1. Human STX4 Protein expressed in Escherichia coli (E. coli) - ABIN1098360 : Yang, Coker, Kim, Mora, Thurmond, Davis, Yang, Williamson, Shulman, Pessin: Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance. in The Journal of clinical investigation 2001 (PubMed)
    Show all 2 references for ABIN1098360

More Proteins for Syntaxin 4 (STX4) Interaction Partners

Human Syntaxin 4 (STX4) interaction partners

  1. When the expression of STX4 mRNA was inhibited with short or small interfering, or silencing, RNA in macrophages, the survival of Brucella melitensis was significantly reduced.

  2. Syntaxin-4 has a role in mediating exocytosis of pre-docked and newcomer insulin (show INS Proteins) granules underlying biphasic glucose-stimulated insulin (show INS Proteins) secretion in human pancreatic beta cells

  3. Increased level of SNAP23 (show SNAP23 Proteins)-Syntaxin4-VAMP7 (show VAMP7 Proteins) interaction correlates with decreased Syntaxin4 phosphorylation and trafficking of MT1-MMP (show MMP14 Proteins) to invadopodia during cellular invasion.

  4. upregulation of Syntaxin 4 is sufficient to significantly improve insulin (show INS Proteins) secretory function to human type 2 diabetes islets retaining low levels of residual function

  5. STX4 is implicated in the antibody secretion.

  6. Syntaxin-4 plays a vital role in exocytosis of IgE from plasma cells. Knock-down of syntaxin-4, but not VAMP3 dramatically reduced IgE secretion from U266 plasma cells causing it to accumulate in the cell.

  7. These results revealed, for the first time, the extracellular role of syntaxin4 and shed light on the division of the extracellular effects exerted by epimorphin (show STX2 Proteins) and syntaxin4 on keratinocyte cornification.

  8. Syntaxin 4 activation and insulin (show INS Proteins) release in the absence of the glucose stimulus, consistent with nitrosative stress and dysfunctional exocytosis

  9. Stx4 is an essential postsynaptic component for synaptic plasticity in hippocampal neurons.

  10. Syntaxin 4 is required for acid sphingomyelinase (show SMPD1 Proteins) activity and apoptotic function.

Mouse (Murine) Syntaxin 4 (STX4) interaction partners

  1. Syn4 transgenic mice with high level expression of Syn4 had a significant extension of lifespan (33% increase in median) and showed increased peripheral insulin (show INS Proteins) sensitivity, even at ages where controls exhibited age-related insulin (show INS Proteins) resistance.

  2. Non-directional stimulation with extracellular syntaxin-4 induces a dramatic morphological change in teratocarcinoma F9 cells and in several endodermal markers, both of which effects are reminiscent of the cells treated with all-trans retinoic acid.

  3. Delivery of GLUT4 (show SLC2A4 Proteins) to the plasma membrane is mediated by formation of functional SNARE (show VTI1B Proteins) complexes containing syntaxin4, SNAP23 (show SNAP23 Proteins), and VAMP2 (show VAMP2 Proteins).

  4. data support a mechanistic model for gelsolin's role in insulin (show INS Proteins) exocytosis: gelsolin (show GSN Proteins) clamps unsolicited soluble N-ethylmaleimide-sensitive factor (show NSF Proteins) attachment receptor-regulated exocytosis through association with Syn4 which is relieved upon stimulus-induced calcium influx to activate gelsolin (show GSN Proteins) to facilitate insulin (show INS Proteins) exocytosis

  5. Syntaxin 4 activation and insulin (show INS Proteins) release in the absence of the glucose stimulus, consistent with nitrosative stress and dysfunctional exocytosis

  6. functions as the necessary t-SNARE (show VTI1B Proteins) protein responsible for correct fusion of the GLUT8 (show SLC2A8 Proteins)-containing vesicle with the plasma membrane in the mouse blastocyst

  7. Interacts with tomosyn (show STXBP5 Proteins) and plays a role in insulin (show INS Proteins)-stimulated GLUT4 (show SLC2A4 Proteins) translocation.

  8. female Syn4 transgenic mice exhibited an increased rate of glucose clearance during glucose tolerance tests that was repressible by the administration of tetracycline

  9. Data show that Munc18c (show STXBP3 Proteins) binds to monomeric syntaxin4 and the N-terminal 29 amino acids of syntaxin4 are necessary for this interaction.

  10. One mechanism accounting for the PDGF (show PDGFA Proteins) induction of Glut4 (show SLC2A4 Proteins) translocation is the suppression of the Munc18c (show STXBP3 Proteins) negative regulation of Syntaxin 4 function.

Syntaxin 4 (STX4) Protein Profile

Protein Summary

Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity).

Gene names and symbols associated with Syntaxin 4 Proteins (STX4)

  • Syntaxin 4 (Syx4)
  • syntaxin 4 (STX4)
  • syntaxin 4 (stx4)
  • syntaxin 4 (Stx4)
  • syntaxin 4A (placental) (Stx4a)
  • CG2715 protein
  • Dmel\\CG2715 protein
  • DmSyx4 protein
  • Dm Syx4 protein
  • EG:95B7.1 protein
  • EG:95B7.11 protein
  • p35-2 protein
  • Stx4 protein
  • Stx4a protein
  • Syn-4 protein
  • Syn4 protein
  • syntaxin4 protein
  • Syx protein
  • Syx-4 protein
  • syx4 protein

Protein level used designations for Syntaxin 4 Proteins (STX4)

CG2715-PA , CG2715-PB , Syx4-PA , Syx4-PB , syntaxin , syntaxin 4 , renal carcinoma antigen NY-REN-31 , syntaxin 4A (placental) , syntaxin-4

GENE ID SPECIES
31269 Drosophila melanogaster
489919 Canis lupus familiaris
493473 Xenopus (Silurana) tropicalis
734915 Xenopus laevis
6810 Homo sapiens
81803 Rattus norvegicus
508675 Bos taurus
20909 Mus musculus
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