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anti-Syntaxin Binding Protein 1 (STXBP1) Antibodies

STXBP1 encodes a syntaxin-binding protein. Additionally we are shipping Syntaxin Binding Protein 1 Proteins (8) and Syntaxin Binding Protein 1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
STXBP1 25558 P61765
STXBP1 6812 P61764
STXBP1 20910 O08599
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Top anti-Syntaxin Binding Protein 1 Antibodies at

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COS7 cells treated with PMA 125... 100 μg Log in to see 2 to 3 Days
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated IHC, ELISA, WB ABIN185107 (0.1µg/ml) staining of Human Brain lysate (35µg protein in ... 100 μg Log in to see 4 to 5 Days
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcin... Immunofluorescence analysis of NIH-3T3 cells, using MUNC-18a (Ab-313) ... 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Munc-18 on a rat cerebrum lysate. Lane 1: 1:5... Immunohistochemical staining for Munc-18 on a formalin-fixed, paraffin... 50 μg Log in to see 5 to 6 Days
Cow Rabbit Un-conjugated WB   0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Anti- Munc18-1 Picoband antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IF, IHC (p), ELISA Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days

STXBP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Syntaxin Binding Protein 1 Antibodies

  1. Human Monoclonal STXBP1 Primary Antibody for IF, IP - ABIN967910 : Fisher, Pevsner, Burgoyne: Control of fusion pore dynamics during exocytosis by Munc18. in Science (New York, N.Y.) 2001 (PubMed)
    Show all 5 references for ABIN967910

  2. Cow (Bovine) Polyclonal STXBP1 Primary Antibody for WB - ABIN318802 : Chakarian, Durbin, Varekamp, Yarmoff: Formation of surface F centers on CaF2/Si(111). in Physical review. B, Condensed matter 1999 (PubMed)

  3. Human Polyclonal STXBP1 Primary Antibody for ELISA, WB - ABIN1531345 : Swanson, Steel, Valle: Identification and characterization of the human ortholog of rat STXBP1, a protein implicated in vesicle trafficking and neurotransmitter release. in Genomics 1998 (PubMed)

  4. Chicken Polyclonal STXBP1 Primary Antibody for WB - ABIN2792301 : Saitsu, Kato, Mizuguchi, Hamada, Osaka, Tohyama, Uruno, Kumada, Nishiyama, Nishimura, Okada, Yoshimura, Hirai, Kumada, Hayasaka, Fukuda, Ogata, Matsumoto: De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy. in Nature genetics 2008 (PubMed)

More Antibodies against Syntaxin Binding Protein 1 Interaction Partners

Human Syntaxin Binding Protein 1 (STXBP1) interaction partners

  1. Reduced expression of STXBP1 leads to changes in the expression and localization of syntaxin-1 (show STX1A Antibodies) in pluripotent stem cells from epileptic encephalopathy patient.

  2. Seizure severity and intellectual disability were connected to STXBP1 encephalopathy patients.

  3. partial STXBP1 loss of function robustly impairs neurotransmitter release in human neurons, and suggest that heterozygous STXBP1 mutations cause early epileptic encephalopathy specifically through a presynaptic impairment.

  4. The case described suggests a relationship between the Rett syndrome and the STXBP1 gene not described so far, making the search for STXBP1 gene mutations advisable in patients with Rett syndrome and early onset of epilepsy.

  5. A de novo mutation in STXBP1 was detected with exome sequencing together with profound impairment of complex I of the mitochondrial respiratory chain on muscle biopsy. Findings implicate a secondary impairment of mitochondrial function.

  6. Epileptic encephalopathy related to mutations in the STXBP1 genes.

  7. In vitro interaction assays indicated that Doc2b (show DOC2B Antibodies) is required to bridge the interaction between Munc18c (show STXBP3 Antibodies) and Munc18-1 in the macromolecular complex; Munc18c (show STXBP3 Antibodies) and Munc18-1 failed to associate in the absence of Doc2b (show DOC2B Antibodies)

  8. STXBP1 gene mutation was found in 1 out of 11 patients

  9. STXBP1 mutations associated with early epileptic encephalopathies.

  10. Recruitment of STXBP1 by the Rab27A (show RAB27A Antibodies) effector SYTL4 (show SYTL4 Antibodies) promotes Weibel-Palade body exocytosis.

Mouse (Murine) Syntaxin Binding Protein 1 (STXBP1) interaction partners

  1. In this studying the Munc18-1-/- nervous system, we demonstrate that synaptic activity is dispensable for the early formation of spinal motor circuits at the levels of axon guidance, differentiation of transcriptional identity, and mRNA expression.

  2. Vamp2 (show VAMP2 Antibodies) mutations that impair Munc18-1 binding inhibit spontaneous as well as evoked neurotransmitter release, providing evidence for the Vamp2 (show VAMP2 Antibodies)-regulating function of Munc18-1 in synaptic exocytosis.

  3. A dynamic PKC (show PKC Antibodies) phosphorylation/de-phosphorylation cycle of Munc18-1 drives short-term enhancement of transmitter release during post-tetanic potentiation.

  4. miR (show MLXIP Antibodies)-218 and miR (show MLXIP Antibodies)-322 directly interact with Stxbp1 by targeting the 3'UTR (show UTS2R Antibodies) of its mRNA.

  5. Munc18-1 levels correlate with synaptic strength.

  6. Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.

  7. [review] Regulation of cortical F-actin is a shared function of Sec1/Munc18-like proteins; a way to gain more insight in the molecular mechanism underlying the Munc18-1-mediated cortical F-actin regulation is proposed.

  8. The N-terminal syntaxin-1 (show STX1A Antibodies) domains mediate different functions in synaptic vesicle fusion, probably via formation of distinct Munc18/SNARE (show VTI1B Antibodies)-protein complexes.

  9. SNAREpin assembly by Munc18-1 requires previous vesicle docking by synaptotagmin 1 (show SYT1 Antibodies).

  10. a novel indirect role for Munc18-1 in facilitating syntaxin 4 (show STX4 Antibodies)-mediated granule pre-docking to support first-phase insulin (show INS Antibodies) exocytosis.

Zebrafish Syntaxin Binding Protein 1 (STXBP1) interaction partners

  1. Epilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish.

Syntaxin Binding Protein 1 (STXBP1) Antigen Profile

Protein Summary

This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with STXBP1

  • syntaxin binding protein 1 (stxbp1) antibody
  • syntaxin binding protein 1 (Tb09.160.0780) antibody
  • syntaxin binding protein 1 (STXBP1) antibody
  • syntaxin binding protein 1 (Stxbp1) antibody
  • syntaxin binding protein 1a (stxbp1a) antibody
  • AI317162 antibody
  • AI326233 antibody
  • ANC18HA antibody
  • fj43h10 antibody
  • hunc18 antibody
  • MGC88906 antibody
  • MGC146482 antibody
  • MMS10-G antibody
  • Ms10g antibody
  • Munc-18a antibody
  • MUNC18-1 antibody
  • N-sec1 antibody
  • nsec1 antibody
  • NSEC1A antibody
  • P67 antibody
  • Rb-sec1 antibody
  • RBSEC1 antibody
  • rbSec1A antibody
  • rbSec1B antibody
  • rop antibody
  • Sec1 antibody
  • stxbp1 antibody
  • Sxtbp1 antibody
  • UNC18 antibody
  • Unc18-1 antibody
  • UNC18A antibody
  • Unc18h antibody
  • wu:fj36d12 antibody
  • wu:fj43h10 antibody
  • zgc:114171 antibody

Protein level used designations for STXBP1

syntaxin binding protein 1 , Ras opposite , syntaxin-binding protein 1-like , p67 , protein unc-18 homolog 1 , protein unc-18 homolog A , syntaxin-binding protein 1 , unc-18 homolog , unc-18-1 , unc-18A , N-Sec1 , neuronal SEC1 , unc18-1 , UNC-18 homolog , minisatellite 10g detected by probe MMS10 , syntaxin 1-binding protein

448217 Xenopus (Silurana) tropicalis
779976 Xenopus (Silurana) tropicalis
3660246 Trypanosoma brucei TREU927
100397821 Callithrix jacchus
25558 Rattus norvegicus
6812 Homo sapiens
20910 Mus musculus
404293 Gallus gallus
282378 Bos taurus
100101272 Xenopus laevis
100173563 Pongo abelii
574003 Danio rerio
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