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Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Additionally we are shipping STXBP4 Antibodies (21) and many more products for this protein.
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meta-analysis suggested that polymorphism STXBP4/COX11 rs6504950 variant was significantly associated with breast cancer risk; the A allele of rs6504950 decreased the risk of breast cancer
Syntaxin 4 (show STX4 Proteins) and Synip (syntaxin 4 interacting protein) regulate insulin (show INS Proteins) secretion in the pancreatic beta HC-9 (show PSMA4 Proteins) cells
Stxbp4 and RACK1 (show GNB2L1 Proteins), two scaffold proteins, play central roles in balancing DeltaNp63 protein levels. While Stxbp4 functions to stabilize DeltaNp63 proteins, RACK1 (show GNB2L1 Proteins) targets DeltaNp63 for degradation.
Serine 99 phosphorylation of Synip is required for Glut4 (show SLC2A4 Proteins) translocation and glucose uptake in both adipocytes and podocytes.
synip binding did not prevent the pairing of syntaxin-4 (show STX4 Proteins) with SNAP-23 (show SNAP23 Proteins) to form the binary t-SNARE (show VTI1B Proteins) complex
By altering the levels of individual components of the VAMP3 (show VAMP3 Proteins)/Stx4 (show STX4 Proteins)/SNAP23 (show SNAP23 Proteins) complex we show here that this SNARE (show VTI1B Proteins) complex regulates efficient macrophage adhesion, spreading and migration on fibronectin (show FN1 Proteins).
Syntaxin 4 (show STX4 Proteins)-based SNARE (show VTI1B Proteins) complexes are essential for biphasic insulin (show INS Proteins) granule fusion in pancreatic beta-cells.
Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity).
syntaxin binding protein 4
, STX4-interacting protein
, syntaxin 4 interacting protein
, syntaxin 4-interacting protein
, syntaxin-binding protein 4