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SNTG2 encodes a protein belonging to the syntrophin family. Additionally we are shipping SNTG2 Antibodies (35) and SNTG2 Proteins (3) and many more products for this protein.
MYT1L and the SNTG2 genes within the reported region could probably relate to the phenotypic discordance of the monozygotic twins.
role in regulating SCN5A (show SCN5A ELISA Kits) gating by a PDZ domain (show INADL ELISA Kits)-mediated interaction
A de novo binding partner of X-linked neuroligin 4 and neuroligin 3, which correlates with autism-related mutations.
Gamma1-Syntrophin (show SNTG1 ELISA Kits) is highly expressed in brain and is specifically localized in hippocampal pyramidal neurons, Purkinje neurons in cerebellum, and cortical neurons. gamma2-Syntrophin is expressed in many tissues including skeletal muscle.
This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
syntrophin, gamma 2