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Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) ELISA Kits

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SNCA SNCA 20617 O55042
Anti-Human SNCA SNCA 6622 P37840
Anti-Rat SNCA SNCA 29219 P37377
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More ELISA Kits for Synuclein, alpha (Non A4 Component of Amyloid Precursor) Interaction Partners

Rhesus Monkey Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) interaction partners

  1. Overexpression of mutant alpha-synuclein causes age-dependent pathological changes in brain.

Mouse (Murine) Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) interaction partners

  1. Data suggest the produced mouse lines represent a set of useful tools for studies of alpha-synuclein normal function and the role of this protein in disease pathogenesis.

  2. that loss of glucocerebrosidase (show GBA ELISA Kits) function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation

  3. provides evidence for a novel interaction of alpha-synuclein and SOD1 (show SOD1 ELISA Kits) that might be relevant for neurodegenerative diseases

  4. It found that chromosome 1 harbors an expression quantitative trait locus that modulates Sncg (show SNCG ELISA Kits) expression in the mouse retina, and identified the prefoldin-2 (PFDN2 (show PFDN2 ELISA Kits)) gene as the candidate upstream modulator of Sncg (show SNCG ELISA Kits) expression.

  5. The response of CPLX1 (show CPLX1 ELISA Kits) and Foxp1 (show FOXP1 ELISA Kits) levels to SNCA deficiency supports the notion that these factors are regulated by altered physiological function of alpha-synuclein.

  6. The pattern of expression and distribution of alpha-synuclein during the development of ciliary body and iris of mice, chick and fish data concluded that alpha-synuclein has important cellular function during eye development of studied animals.

  7. Longitudinal Metabolomics Profiling of Parkinson's Disease-Related alpha-Synuclein A53T Transgenic Mice.

  8. This would suggest that as complex I-deficient cells have already adapted to their mitochondrial defect, the subsequent toxic effects of alpha-synuclein are reduced.

  9. The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice and has an important role.

  10. These findings support a reciprocal modulatory interaction of alpha-syn and synapsin III (show SYN3 ELISA Kits) in the regulation of dopamine neuron synaptic function.

Human Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) interaction partners

  1. Samples were taken from six sites and immunostained for phosphorylated alpha-synuclein

  2. This study deminstrated that alpha-Synuclein methylation levels depended on disease status, sex, age, and the genotype of rs3756063.

  3. HMGB1 (show HMGB1 ELISA Kits) or Beclin1 (show BECN1 ELISA Kits) upregulate alpha-synuclein degradation, ameliorating alpha-synuclein-mediated autophagy reduction in PC12 cells.

  4. his study showed that decreased Levels of monomeric Alpha-Synuclein correlate with Duration of Dementia.

  5. Chemical cross-linking in combination with solution-state NMR and multiangle static light scattering (MALS (show NCR3 ELISA Kits)) of alpha-Syn particles reveal a high-order protein-lipid entity composed of approximately 8-10 alpha-Syn molecules.

  6. Results imply that accumulating alpha-synuclein severely affects hippocampal neurogenesis paralleled by impaired 5-HT (show DDC ELISA Kits) neurotransmission prior to the onset of aggregation pathology and overt motor deficits in a transgenic rat Parkinson's disease model

  7. utility of alpha-synuclein as biofluid marker in neurodegenerative diseases

  8. single-molecule Forster Resonance Energy Transfer to visualize directly the protein self-assembly process by wild-type alpha-synuclein and A53T, A30P and E46K mutants and to compare the structural properties of the ensemble of oligomers generated.

  9. An alpha-synuclein mutant inhibited two forms of endocytosis, slow and rapid, in central nerve terminals.

  10. that loss of glucocerebrosidase (show GBA ELISA Kits) function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation

Cow (Bovine) Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) interaction partners

  1. analysis of membrane curvature sensing by amphipathic helices using alpha-synuclein and annexin B12 (show TNFAIP1 ELISA Kits) [ANXB12]

  2. Immunocytochemistry shows alpha synuclein localized to the Golgi apparatus and vesicles of bovine adrenal medullary chromaffin cells, consistent with its putative role in vesicular function within synapses.

Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) Antigen Profile

Antigen Summary

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

Gene names and symbols associated with SNCA

  • synuclein, alpha (non A4 component of amyloid precursor) (SNCA) antibody
  • alpha-synuclein (LOC100359228) antibody
  • alpha-synuclein-like (SNCA) antibody
  • synuclein, alpha (Snca) antibody
  • synuclein, alpha (non A4 component of amyloid precursor) (Snca) antibody
  • alphaSYN antibody
  • NACP antibody
  • PARK1 antibody
  • PARK4 antibody
  • PD1 antibody

Protein level used designations for SNCA

alpha SYN , alpha-synuclein , non-A beta component of AD amyloid , non-A4 component of amyloid , non A-beta component of AD amyloid , synuclein alpha-140 , alpha synuclein

GENE ID SPECIES
100053270 Equus caballus
100359228 Oryctolagus cuniculus
706985 Macaca mulatta
20617 Mus musculus
6622 Homo sapiens
29219 Rattus norvegicus
478478 Canis lupus familiaris
282857 Bos taurus
641350 Sus scrofa
395393 Gallus gallus
100725375 Cavia porcellus
100294604 Ovis aries
100190854 Pongo abelii
461375 Pan troglodytes
100984304 Pan paniscus
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