Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Additionally we are shipping SNCA Antibodies (650) and SNCA Kits (67) and many more products for this protein.
Showing 10 out of 68 products:
Human SNCA Protein expressed in Escherichia coli (E. coli) - ABIN1046507
Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. in Proceedings of the National Academy of Sciences of the United States of America 1994
Show all 3 references for ABIN1046507
Mouse (Murine) SNCA Protein expressed in Escherichia coli (E. coli) - ABIN667142
Kim: Evidence that the precursor protein of non-A beta component of Alzheimer's disease amyloid (NACP) has an extended structure primarily composed of random-coil. in Molecules and cells 1997
Show all 3 references for ABIN667142
Human SNCA Protein expressed in Escherichia coli (E. coli) - ABIN2005039
Lee, Choi, Lee: Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form. in The Journal of biological chemistry 2002
Show all 2 references for ABIN2005039
Rat (Rattus) SNCA Protein expressed in Rabbit - ABIN1742284
Jüttner, Moré, Das, Babich, Meier, Henning, Erdmann, Mu Ller, Otto, Grantyn, Rathjen: Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity. in Neuron 2005
study examined the spatial and temporal expression patterns of three synuclein genes (snca, sncbb, sncg (show SNCG Proteins)) during embryogenesis
Data suggest the produced mouse lines represent a set of useful tools for studies of alpha-synuclein normal function and the role of this protein in disease pathogenesis.
that loss of glucocerebrosidase function may contribute to SNCA accumulation through inhibition of autophagy via PPP2A inactivation
provides evidence for a novel interaction of alpha-synuclein and SOD1 (show SOD1 Proteins) that might be relevant for neurodegenerative diseases
It found that chromosome 1 harbors an expression quantitative trait locus that modulates Sncg (show SNCG Proteins) expression in the mouse retina, and identified the prefoldin-2 (PFDN2 (show PFDN2 Proteins)) gene as the candidate upstream modulator of Sncg (show SNCG Proteins) expression.
The response of CPLX1 and Foxp1 levels to SNCA deficiency supports the notion that these factors are regulated by altered physiological function of alpha-synuclein.
The pattern of expression and distribution of alpha-synuclein during the development of ciliary body and iris of mice, chick and fish data concluded that alpha-synuclein has important cellular function during eye development of studied animals.
Longitudinal Metabolomics Profiling of Parkinson's Disease-Related alpha-Synuclein A53T Transgenic Mice.
This would suggest that as complex I-deficient cells have already adapted to their mitochondrial defect, the subsequent toxic effects of alpha-synuclein are reduced.
The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice and has an important role.
These findings support a reciprocal modulatory interaction of alpha-syn and synapsin III (show SYN3 Proteins) in the regulation of dopamine neuron synaptic function.
Samples were taken from six sites and immunostained for phosphorylated alpha-synuclein
This study deminstrated that alpha-Synuclein methylation levels depended on disease status, sex, age, and the genotype of rs3756063.
HMGB1 or Beclin1 upregulate alpha-synuclein degradation, ameliorating alpha-synuclein-mediated autophagy reduction in PC12 cells.
his study showed that decreased Levels of monomeric Alpha-Synuclein correlate with Duration of Dementia.
Chemical cross-linking in combination with solution-state NMR and multiangle static light scattering (MALS (show NCR3 Proteins)) of alpha-Syn particles reveal a high-order protein-lipid entity composed of approximately 8-10 alpha-Syn molecules.
Results imply that accumulating alpha-synuclein severely affects hippocampal neurogenesis paralleled by impaired 5-HT (show DDC Proteins) neurotransmission prior to the onset of aggregation pathology and overt motor deficits in a transgenic rat Parkinson's disease model
utility of alpha-synuclein as biofluid marker in neurodegenerative diseases
single-molecule Forster Resonance Energy Transfer to visualize directly the protein self-assembly process by wild-type alpha-synuclein and A53T, A30P and E46K mutants and to compare the structural properties of the ensemble of oligomers generated.
An alpha-synuclein mutant inhibited two forms of endocytosis, slow and rapid, in central nerve terminals.
analysis of membrane curvature sensing by amphipathic helices using alpha-synuclein and annexin B12 (show TNFAIP1 Proteins) [ANXB12]
Immunocytochemistry shows alpha synuclein localized to the Golgi apparatus and vesicles of bovine adrenal medullary chromaffin cells, consistent with its putative role in vesicular function within synapses.
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
, alpha SYN
, non-A beta component of AD amyloid
, non-A4 component of amyloid
, non A-beta component of AD amyloid
, synuclein alpha-140
, alpha synuclein