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T, Brachyury Homolog (Mouse) (T) ELISA Kits

The protein encoded by T is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. Additionally we are shipping T, Brachyury Homolog (Mouse) Antibodies (24) and T, Brachyury Homolog (Mouse) Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse T T 20997 P20293
Anti-Human T T 6862 O15178
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More ELISA Kits for T, Brachyury Homolog (Mouse) Interaction Partners

Mouse (Murine) T, Brachyury Homolog (Mouse) (T) interaction partners

  1. data confirmed that Brachyury (show TBX1 ELISA Kits) might contribute to hypoxia-induced EMT (show ITK ELISA Kits) of breast cancer and trigger HIF-1alpha (show HIF1A ELISA Kits) expression via PTEN/Akt (show AKT1 ELISA Kits) signaling

  2. Results showed that the expression levels of HDAC1 (show HDAC1 ELISA Kits) and 3 are decreased gradually during embryonic stem cells (ESCs (show NR2E3 ELISA Kits)) mesodermal differentiation and interact physically with Bry protein, which is critical for mesodermal lineage commitment.

  3. Epithelial-to-mesenchymal transition (EMT (show ITK ELISA Kits)) initiates the controlled differentiation of embryonic stem cells, which is both fuelled and terminated by the action of brachyury (show TBX1 ELISA Kits), whose expression is dependent on the EMT (show ITK ELISA Kits) and beta-catenin (show CTNNB1 ELISA Kits) activity.

  4. results thus chart a comprehensive map of the Brachyury (show TBX1 ELISA Kits)-mediated gene-regulatory network and how it influences in vivo developmental homeostasis and coordination

  5. T (BRACHYURY), a classical and conserved mesodermal factor, was essential for robust activation of Blimp1 and Prdm14, two of the germline determinants.

  6. In vivo knockdown of Brachyury (show TBX1 ELISA Kits) results in skeletal defects and urorectal malformations resembling caudal (show CAD ELISA Kits) regression syndrome

  7. UTX (show KDM6A ELISA Kits) controls mesoderm differentiation and Brachyury (show TBX1 ELISA Kits) expression independent of H3K27 demethylase (show MBD2 ELISA Kits) activity; UTX (show KDM6A ELISA Kits) and UTY (show UTY ELISA Kits) are functionally redundant in ES cell differentiation and early embryonic development

  8. We found Tcf3 (show TCF7L1 ELISA Kits) as a potential target of gene repression by Nkx1-2 (show NKX1-2 ELISA Kits), and the down-regulation of Tcf3 (show TCF7L1 ELISA Kits) was partly required for effective activation of Brachyury (show TBX1 ELISA Kits) by Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling

  9. Data show that expression of Brachyury (show TBX1 ELISA Kits) targets Axin2 (show AXIN2 ELISA Kits), Fgf8 (show FGF8 ELISA Kits) and Wnt3a (show WNT3A ELISA Kits), is down regulated in Brachyury (show TBX1 ELISA Kits) mutant embryos.

  10. Id1 (show ID1 ELISA Kits) regulates self-renewal of embryonic stem cells by regulating levels of Nanog (show NANOG ELISA Kits) and Brachyury (show TBX1 ELISA Kits).

Xenopus laevis T, Brachyury Homolog (Mouse) (T) interaction partners

  1. DN-Xbra inhibits PV.1 expression and that the suppression of PV.1 reduces overall BMP signaling by inducing chordin (show CHRD ELISA Kits) and goosecoid expression.

  2. EphA4-dependent Brachyury (show TBX1 ELISA Kits) expression is required for dorsal mesoderm involution in the Xenopus gastrula.

  3. This is the first report to demonstrate that Brachyury (show TBX1 ELISA Kits) might affect the cytoskeletal structure through regulating the expression of an intermediate filament protein (show INA ELISA Kits), vimentin.

  4. Data suggest a dual regulation in which XESR5 produces a competent area for mesoderm formation by suppressing the gene expression of XESR1 (show ESR1 ELISA Kits), while XESR1 (show ESR1 ELISA Kits) sharpens the boundary of Xbra expression.

  5. controls the early homeobox (show PRRX1 ELISA Kits) gene expression domain in the animal-vegetal direction

  6. findings reveal that the N-terminal domain that restricts the inducing activity of Xbra interacts with Smad1 (show SMAD1 ELISA Kits)

  7. Embryo elongation can occur through the synergistic effect(s) of the organizer molecule chordin (show CHRD ELISA Kits), and the 'verall posteriorizing molecule Xbra.

  8. AP-2rep (show KLF12 ELISA Kits) is involved in the morphogenesis of the mesoderm at the gastrula stage, via the brachyury (show TBX1 ELISA Kits) and/or Wnt (show WNT2 ELISA Kits) pathways.

Human T, Brachyury Homolog (Mouse) (T) interaction partners

  1. Brachyury (show TBX1 ELISA Kits) expression promotes lung cancer cell proliferation and invasion, and correlates with reduced patient survival.

  2. Nuclear brachyury (show TBX1 ELISA Kits) expression is prevalent in embryonal carcinoma, seminoma, and small cell carcinoma of the lung but very rare in common carcinomas, sarcomas, and melanoma.

  3. Elevated Brachyury (show TBX1 ELISA Kits) facilitates hepatocellular carcinoma metastasis by promoting EMT (show ITK ELISA Kits) via PTEN/Akt (show AKT1 ELISA Kits)/Snail (show SNAI1 ELISA Kits)-dependent pathway.

  4. we found that Brachyury (show TBX1 ELISA Kits) expression was inversely correlated with CCL2 (show CCL2 ELISA Kits) and CCL4 (show CCL4 ELISA Kits) expression in human lung tumors

  5. Brachyury (show TBX1 ELISA Kits) plays an important role in regulating TGF beta 1 (show TGFB1 ELISA Kits)-mediated renal epithelial mesenchymal transition and could be an attractive target for progression of renal disease therapies

  6. the present study suggests that Brachyury (show TBX1 ELISA Kits) plays an important role in prostate cancer aggressiveness and points, for the first time, to Brachyury (show TBX1 ELISA Kits) as a significant predictor of poor prostate cancer prognosis

  7. Brachyury (show TBX1 ELISA Kits) separates chordoma from cytomorphologic mimics with high sensitivity and specificity in small biopsies.

  8. Brachyury (show TBX1 ELISA Kits) expression may useful for the differential diagnosis of renal hemangioblastoma from other neoplastic histological mimickers. [Review]

  9. Brachyury (show TBX1 ELISA Kits) knockdown reduces invasiveness and chemoresistance and radioresistance of cancer stem cells in vivo.

  10. The level of brachyury (show TBX1 ELISA Kits) expression in breast cancer cells was positively associated with their ability to invade the extracellular matrix, efficiently form mammospheres in vitro, and resist the cytotoxic effect of docetaxel

T, Brachyury Homolog (Mouse) (T) Antigen Profile

Antigen Summary

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with T

  • brachyury (T) antibody
  • T, brachyury homolog (t-a) antibody
  • T, brachyury homolog (mouse) (T) antibody
  • bra antibody
  • brachyury antibody
  • bu antibody
  • CH-T antibody
  • cou antibody
  • D17Mit170 antibody
  • Low antibody
  • Lr antibody
  • me75 antibody
  • ntl antibody
  • t antibody
  • T1 antibody
  • ta antibody
  • TFT antibody
  • Tl2 antibody
  • Tl3 antibody
  • X-bra antibody
  • xbra antibody
  • Xbrachyury antibody

Protein level used designations for T

brachyury protein , brachyury-like 2 , brachyury-like 3 , low ratio , protein T , T, brachyury homolog a , brachyury (T) , T brachyury homolog , T brachyury protein

20997 Mus musculus
399275 Xenopus laevis
6862 Homo sapiens
395782 Gallus gallus
403653 Canis lupus familiaris
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