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T-Box 18 Proteins (TBX18)

TBX18s codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. Additionally we are shipping T-Box 18 Antibodies (53) and T-Box 18 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TBX18 9096 O95935
TBX18 76365 Q9EPZ6
Rat TBX18 TBX18 315870  
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Top T-Box 18 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details

TBX18 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

More Proteins for T-Box 18 (TBX18) Interaction Partners

Human T-Box 18 (TBX18) interaction partners

  1. Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development.

  2. The DNA sequence variants within the TBX18 gene promoter identified in ventricular septal defects (VSD) patients may be involved in the VSD etiology.

  3. connexin43 (show GJA1 Proteins) transcriptional suppression by TBX18 undermines cardiomyocyte cell-cell electrical coupling

  4. Tbx18 interacts with Gata4 (show GATA4 Proteins) and Nkx2-5 (show NKX2-5 Proteins) and competes Tbx5 (show TBX5 Proteins)-mediated activation of the cardiac Natriuretic peptide precursor type a-promoter. Tbx18 down-regulates Tbx6 (show TBX6 Proteins)-activated Delta-like 1 (show DLL1 Proteins) expression in the somitic mesoderm in vivo

Zebrafish T-Box 18 (TBX18) interaction partners

  1. Areas of strong tbx18 expression are found in the developing somitic and presomitic mesoderm, in the heart and in pectoral fin mesenchyme, as well as the ventral neuroectoderm and the developing palate

Mouse (Murine) T-Box 18 (TBX18) interaction partners

  1. The temporal suppression of Tbx18 gene expression by the hypermethylation of its promoter seems to trigger the differentiation of mesenchymal cells into hypertrophic chondrocytes in the early stages of endochondral ossification.

  2. A distant downstream enhancer directs essential expression of Tbx18 in urogenital tissues.

  3. Tbx18 has a role in normal development of vasculature network and glomerular mesangium in the mammalian kidney

  4. Tbx18, a T-box family member highly expressed in the proepicardium, controls critical early steps in coronary development.

  5. Tbx18 is required to prepattern mouse ureteric mesenchyme

  6. Tbx18 and Wt1 (show WT1 Proteins) directly bound to the Slug (show SNAI2 Proteins) promoter region and regulated Slug (show SNAI2 Proteins) expression

  7. Tbx18 is dispensable for epicardial development but that a transcriptional activator form of Tbx18 is sufficient to induce premature smooth muscle differentiation of epicardial cells.

  8. Tbx18 is dispensable for normal dermal papilla function.

  9. Data show that Tbx18- and Wt1 (show WT1 Proteins)-deficient mice additionally exhibit partial pericardial absence.

  10. phenotypes result from competition between the ectopically expressed Tbx6 (show TBX6 Proteins) and the endogenously expressed Tbx18 and Tbx15 (show TBX15 Proteins) at the binding sites of target genes

T-Box 18 (TBX18) Protein Profile

Protein Summary

This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors.

Gene names and symbols associated with T-Box 18 Proteins (TBX18)

  • T-box 18 (TBX18)
  • T-box 18 (LOC100227912)
  • T-box 18 (tbx18)
  • T-box18 (Tbx18)
  • 2810012F10Rik protein
  • 2810404D13Rik protein
  • TBX18 protein

Protein level used designations for T-Box 18 Proteins (TBX18)

T-box 18 , T-box transcription factor TBX18-like , t-box transcription factor TBX18-like , T-box transcription factor TBX18 , transcription factor Tbx18 , T-box protein 18

GENE ID SPECIES
462861 Pan troglodytes
696007 Macaca mulatta
100065507 Equus caballus
100076100 Ornithorhynchus anatinus
100227912 Taeniopygia guttata
100412573 Callithrix jacchus
100489044 Xenopus (Silurana) tropicalis
100606514 Nomascus leucogenys
395104 Gallus gallus
9096 Homo sapiens
481903 Canis lupus familiaris
517044 Bos taurus
572713 Danio rerio
100152747 Sus scrofa
76365 Mus musculus
315870 Rattus norvegicus
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