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T-Box 19 Proteins (TBX19)

TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. Additionally we are shipping T-Box 19 Antibodies (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TBX19 9095 O60806
TBX19 83993 Q99ME7
Rat TBX19 TBX19 304935  
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Top T-Box 19 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TBX19 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for T-Box 19 (TBX19) Interaction Partners

Human T-Box 19 (TBX19) interaction partners

  1. Identification of nine new TPIT mutations in a large series of congenital isolated ACTH (show POMC Proteins)-deficiency patients.

  2. TPIT is identified as a target autoantigen in 10.5% of patients with lymphocytic hypophysitis.

  3. The coordinate expression of Etv1 (show ETV1 Proteins) with POMC (show POMC Proteins) cell differentiation and its interaction with the highly cell-restricted Tpit factor indicate that Etv1 (show ETV1 Proteins) participates in a combinatorial code for pituitary cell-specific gene expression.

  4. Review. Association of 2 mutations with an ACTH (show POMC Proteins) deficiency is consistent with the role of tbx19 in differentiation of POMC (show POMC Proteins) cells.

  5. TPIT has a role in expression of the pro-opiomelanocortin (show POMC Proteins) gene and terminal differentiation of the pituitary corticotroph lineage, and its mutation causes early onset pituitary ACTH (show POMC Proteins) deficiency

  6. Tpit, along with NGFI-B (show NR4A1 Proteins) and SRC-2 (show NCOA2 Proteins), is part of a transcription regulatory complex assembled on the POMC (show POMC Proteins) promoter in response to hormonal stimulation.

  7. mutations in the TPIT gene, a T-box factor selectively expressed in developing corticotroph cells, have been found in cases of early-onset isolated ACTH (show POMC Proteins) deficiency

  8. TPIT gene mutations is the principal molecular cause of neonatal congenital isolated ACTH (show POMC Proteins) deficiency

  9. We report largest series of congenital ACTH (show POMC Proteins) deficiency and demonstrate molecular mechanism involves Tpit in majority of cases.

  10. Overtransmission of a haplotype GAC (show GLS Proteins) at the TBX19 locus was associated with increased angry/hostility scores among suicide attempters.

Mouse (Murine) T-Box 19 (TBX19) interaction partners

  1. The coordinate expression of Etv1 (show ETV1 Proteins) with POMC (show POMC Proteins) cell differentiation and its interaction with the highly cell-restricted Tpit factor indicate that Etv1 (show ETV1 Proteins) participates in a combinatorial code for pituitary cell-specific gene expression.

  2. Review. Association of 2 mutations with an ACTH (show POMC Proteins) deficiency is consistent with the role of tbx19 in differentiation of POMC (show POMC Proteins) cells.

  3. TPIT has a role in expression of the pro-opiomelanocortin (show POMC Proteins) gene and terminal differentiation of the pituitary corticotroph lineage, and its mutation causes early onset pituitary ACTH (show POMC Proteins) deficiency

  4. Tpit has a role as a negative regulator of gonadotroph differentiation in developing mouse

  5. Tpit and NeuroD1 (show NEUROD1 Proteins) are not essential for early corticotroph commitment. There are different levels of control for commitment of POMC (show POMC Proteins) lineages compared to cell survival or to cell-specific transcription of POMC (show POMC Proteins).

  6. the M86R TPIT mutation is defining an important surface of the T domain for multiple protein interactions and for transcription

T-Box 19 (TBX19) Protein Profile

Protein Summary

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.

Gene names and symbols associated with T-Box 19 Proteins (TBX19)

  • T-box 19 (TBX19)
  • T-box 19 (LOC100352422)
  • T-box 19 (Tbx19)
  • AU019250 protein
  • CH-TBXT protein
  • D1Ertd754e protein
  • dJ747L4.1 protein
  • TBS19 protein
  • TBX19 protein
  • TBXT protein
  • Tpit protein

Protein level used designations for T-Box 19 Proteins (TBX19)

T-box 19 , T-box transcription factor TBX19-like , T-box factor, pituitary , T-box protein 19 , T-box transcription factor TBX19 , TBS 19 , T-box containing protein , T-box-containing protein TBXT , T-box transcription factor 19

GENE ID SPECIES
699312 Macaca mulatta
748358 Pan troglodytes
100352422 Oryctolagus cuniculus
100403282 Callithrix jacchus
100606186 Nomascus leucogenys
9095 Homo sapiens
395793 Gallus gallus
449029 Canis lupus familiaris
514352 Bos taurus
83993 Mus musculus
304935 Rattus norvegicus
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