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anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) Antibodies

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Additionally we are shipping TIMD4 Proteins (7) and TIMD4 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIMD4 497891  
TIMD4 276891 Q6U7R4
TIMD4 91937 Q96H15
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Top anti-TIMD4 Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TIM-4 in Jurkat lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of TIM-4 in Jurkat cells with TIM-4 antibody at 10 μg/ml. Immunofluorescence of TIM-4 in Jurkat cells with TIM-4 antibody at 20 µg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$632.50
Details
Human Rabbit Un-conjugated WB TIMD4 Antibody (C-term) (ABIN1881886) western blot analysis in human Uterus tissue lysates (35 µg/lane). This demonstrates the TIMD4 antibody detected the TIMD4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rat Alexa Fluor 647 FACS 25 μg Log in to see 10 to 12 Days
$135.88
Details
Mouse Rat PE FACS, IP, ELISA 100 μg Log in to see 10 to 12 Days
$288.07
Details
Mouse Rat PE FACS 100 μg Log in to see 10 to 12 Days
$288.07
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rat Alexa Fluor 647 IF, ICFC, IHC 100 μg Log in to see 10 to 12 Days
$320.68
Details
Mouse Hamster Un-conjugated Func, EIA, IF   0.1 mg Log in to see 6 to 8 Days
$357.50
Details

TIMD4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TIMD4 Antibodies

  1. Mouse (Murine) Monoclonal TIMD4 Primary Antibody for FACS - ABIN2663932 : Rodriguez-Manzanet, Meyers, Balasubramanian, Slavik, Kassam, Dardalhon, Greenfield, Anderson, Sobel, Hafler, Strom, Kuchroo: TIM-4 expressed on APCs induces T cell expansion and survival. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 5 references for ABIN2663932

  2. Human Polyclonal TIMD4 Primary Antibody for WB - ABIN1881886 : Dorfman, Hornick, Shahsafaei, Freeman: The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms. in Human pathology 2010 (PubMed)
    Show all 5 references for ABIN1881886

  3. Mouse (Murine) Monoclonal TIMD4 Primary Antibody for IF, ICFC - ABIN2658022 : Kuchroo, Dardalhon, Xiao, Anderson: New roles for TIM family members in immune regulation. in Nature reviews. Immunology 2008 (PubMed)
    Show all 5 references for ABIN2658022

  4. Human Polyclonal TIMD4 Primary Antibody for EIA, IF - ABIN500917 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)
    Show all 4 references for ABIN500917

  5. Mouse (Murine) Monoclonal TIMD4 Primary Antibody for FACS, IP - ABIN2663930 : Miyanishi, Tada, Koike, Uchiyama, Kitamura, Nagata: Identification of Tim4 as a phosphatidylserine receptor. in Nature 2007 (PubMed)
    Show all 3 references for ABIN2663930

  6. Human Polyclonal TIMD4 Primary Antibody for WB - ABIN318767 : Meyers, Chakravarti, Schlesinger, Illes, Waldner, Umetsu, Kenny, Zheng, Umetsu, DeKruyff, Strom, Kuchroo: TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation. in Nature immunology 2005 (PubMed)
    Show all 2 references for ABIN318767

More Antibodies against TIMD4 Interaction Partners

Mouse (Murine) T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) interaction partners

  1. Blockade of Tim-4 aggravates atherosclerosis in LDL receptor (show LDLR Antibodies) knockout mice likely by prevention of phagocytosis of phosphatidylserine-expressing apoptotic cells and activated T cells by Tim-4-expressing cells.

  2. results indicate that Tim-4 is involved in negative regulation of NO production in macrophages, suggesting the critical role of Tim-4 in immune related diseases

  3. TIM-4 on dendritic cells plays a critical role in hepatic ischemia-reperfusion (IR) injury and may be an efficient target for the prevention of liver or other organ IR injuries.

  4. M2-like TIM-4hiCD169+ tissue-resident macrophages are immunoregulatory and promote engraftment of cardiac allografts, but their influence is diminished by TIM-4-dependent programmed cell death

  5. intrinsic macrophage-specific TIM-4 signaling has indispensable role in innate immunity-driven liver ischemia-reperfusion injury

  6. TIM4 engages integrins as coreceptors to evoke the signal transduction needed to internalize PtdSer-bearing targets such as apoptotic cells.

  7. Tim-4 expression was higher in Behcet's disease (BD) mice than that in BDN mice.

  8. In addition to the known phosphatidylserine(PS) binding pocket, Tim4 has four weaker sites of interaction, making it sensitive to PS surface concentration in a manner capable of differential recognition on the basis of PS exposure level.

  9. the engulfment of apoptotic cells by resident peritoneal macrophages proceeds in two steps: binding to Tim4, a PtdSer receptor, followed by MerTK (show MERTK Antibodies)-mediated cell engulfment

  10. Data suggest that trans-membrane (or T cell) immunoglobulin and mucin (show SLC13A2 Antibodies) (TIM) molecules are expressed in embryonic hematopoietic tissues in chicken and mouse and that in fetal liver, TIM-4 is expressed by myeloid progenitor cells.

Human T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) interaction partners

  1. TIM-4 rs7700944 and not TIM-1 (show ARHGEF5 Antibodies) rs41297579 G>A (-1454) is associated with rheumatoid arthritis(RA) in the present cohort of Egyptian and may be a risk factor for development of RA in Egyptian.

  2. Data showed up-regulation of TIM-4 in lung cancer tissues and a correlation with poor prognosis. Also, TIM-4 was found to promote growth of lung cancer cells by its interaction with integrin alphavbeta3 (show ITGAV Antibodies) through its RGD motif.

  3. Tim-4 expression on monocytes and Tim-4 level in plasma were more highly increased in ankylosing spondylitis patients than in controls.

  4. Our results do not support an association between the rs7700944 polymorphism of the TIM-4 gene and rheumatoid arthritis

  5. Data suggest that genetic polymorphisms in ANGPTL3 (angiopoietin-like 3 (show ANGPTL3 Antibodies) protein), TIMD4 (T cell immunoglobulin mucin-4 (show MUC4 Antibodies)), and apolipoproteins A5 and B are among the genetic determinants of hypertriglyceridemia in Amerindian populations. [REVIEW]

  6. TIM4 expression is promoted by Cockroach allergen Bla (show LACTB Antibodies) g 7 in dendritic cells leading to Th2 polarization

  7. TIM-1 (show ARHGEF5 Antibodies) and TIM-4 are novel targets for ADAM10 (show ADAM10 Antibodies)- and ADAM17 (show ADAM17 Antibodies)-mediated ectodomain shedding.

  8. FG-CC' siRNA blocking interaction of Tim-1 (show ARHGEF5 Antibodies) and Tim-4 can enhance dendritic cell vaccine activity against gastric cancer.

  9. There were four SNPs in the promoter region of TIM4 in asthma patients of Chinese Han population, which were in linkage disequilibrium.

  10. TIM-4 variant or a highly correlated nearby gene of the TIM-4 gene may play a critical role in the pathogenesis of rheumatoid arthritis in many ethnicities.

TIMD4 Antigen Profile

Protein Summary

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1.

Gene names and symbols associated with TIMD4

  • T-cell immunoglobulin and mucin domain containing 4 (Timd4) antibody
  • T-cell immunoglobulin and mucin domain containing 4 (TIMD4) antibody
  • T-cell immunoglobulin and mucin domain containing 4 (timd4) antibody
  • T cell immunoglobulin and mucin domain containing 4 (Timd4) antibody
  • B430010N18Rik antibody
  • MGC99322 antibody
  • RGD1564516 antibody
  • SMUCKLER antibody
  • TIM-4 antibody
  • TIM4 antibody
  • TIMD4 antibody

Protein level used designations for TIMD4

T-cell immunoglobulin and mucin domain containing 4 , T-cell immunoglobulin and mucin domain-containing protein 4 , T-cell membrane protein 4 , TIMD-4 , smuckler , spleen, mucin-containing, knockout of lymphotoxin protein , TIM-4

GENE ID SPECIES
497891 Rattus norvegicus
416250 Gallus gallus
447692 Xenopus laevis
462217 Pan troglodytes
489160 Canis lupus familiaris
507549 Bos taurus
100597340 Nomascus leucogenys
276891 Mus musculus
91937 Homo sapiens
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