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anti-T-Cell Leukemia Homeobox 3 (TLX3) Antibodies

RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Additionally we are shipping TLX3 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TLX3 27140  
TLX3 30012 O43711
TLX3 497881  
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Top anti-TLX3 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TLX3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated WB Western blot analysis of TLX3 over-expressed 293 cell line, cotransfected with TLX3 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of TLX3 expression in transfected 293T cell line by TLX3 monoclonal antibody (M01), clone 2A3. Lane 1: TLX3 transfected lysate(31.9 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TLX3 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IP Immunoprecipitation of TLX3 transfected lysate using anti-TLX3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with TLX3 MaxPab mouse polyclonal antibody (B01) . 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of TLX3 expression in transfected 293T cell line by TLX3 MaxPab polyclonal antibody.Lane 1: TLX3 transfected lysate(32.01 KDa).Lane 2: Non-transfected lysate. TLX3 MaxPab polyclonal antibody. Western Blot analysis of TLX3 expression in human spleen. 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated RNAi, ELISA, WB TLX3 monoclonal antibody (M01), clone 2A3 Western Blot analysis of TLX3 expression in MCF-7 . Western blot analysis of TLX3 over-expressed 293 cell line, cotransfected with TLX3 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with TLX3 monoclonal antibody (M01), clone 2A3. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TLX3 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details

TLX3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Top referenced anti-TLX3 Antibodies

  1. Human Polyclonal TLX3 Primary Antibody for WB - ABIN2777500 : Baak, Gökbuget, Orawa, Schwartz, Hoelzer, Thiel, Burmeister: Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group. in Leukemia 2008 (PubMed)

More Antibodies against TLX3 Interaction Partners

Mouse (Murine) T-Cell Leukemia Homeobox 3 (TLX3) interaction partners

  1. Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP (show CREBBP Antibodies).

  2. Tlx3 uses distinct mechanisms to tightly modulate Prrxl1 (show DRGX Antibodies) activity, either by controlling its transcriptional levels or by increasing Prrxl1 (show DRGX Antibodies) phosphorylation state.

  3. The tlx2 (show TLX2 Antibodies) knockout mice failed to exhibit escape response evoked by dynamic mechanical stimuli but retained the ability to sense innocuous cooling and/or warm and development of a subset of excitatory neurons located in laminae I and II was impaired.

  4. Tlx3 is required for the acquisition of cholinergic phenotype at the late embryonic stage as well as the expression and maintenance of cholinergic peptides

  5. This study demonistrated that Tlx3 and Runx1 (show RUNX1 Antibodies) act in combination to coordinate the development of nociceptors, thermoceptors, and pruriceptors.

  6. Tlx1 (show TLX1 Antibodies)/3 and Ptf1a (show PTF1A Antibodies), the key transcription factors for fate determination of glutamatergic and GABAergic neurons in the dorsal spinal cord

  7. This study found that Tlx3 was required for specification of, and expressed in, glutamatergic neurons. and ectopic expression of Tlx3 was sufficient to suppress GABAergic differentiation and induce formation of glutamatergic neurons.

  8. Lbx1 (show Lbx1 Antibodies) and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes.

  9. The sequential and coordinated expression of the proneural and neuronal subtype-specific genes identifies Tlx3 as a selector gene in ES cells undergoing neural differentiation

Human T-Cell Leukemia Homeobox 3 (TLX3) interaction partners

  1. Immunophenotyping with CD135 (show FLT3 Antibodies) and CD117 predicts the FLT3 (show FLT3 Antibodies), IL-7R and TLX3 gene mutations in childhood T-cell acute leukemia.

  2. Studies suggest that homeobox protein TLX3 expression is not an indicator for the prognosis of pediatric T cell acute lymphocytic leukemia (T-ALL).

  3. these results place TLX1 (show TLX1 Antibodies) and TLX3 at the top of an oncogenic transcriptional network controlling leukemia development, and identify RUNX1 (show RUNX1 Antibodies) as a tumor-suppressor gene in T-ALL

  4. The cortical thymic maturation arrest in T-lineage Acute lymphoblastic leukemias (ALLs) that overexpress TLX1 (show TLX1 Antibodies) or TLX3 is due to binding of TLX1 (show TLX1 Antibodies)/TLX3 to ETS1 (show ETS1 Antibodies).

  5. We found that 22 (21%) out of 110 clinical samples of bladder cancer showed the methylated pattern using the COBRA assay in TLX3. We found a correlation between TLX3 methylation and the sensitivity to cisplatin in the clinical samples by SDI test.

  6. Results identify Tlx3 as a novel target for canonical Wnt (show WNT2 Antibodies) signaling that confers somatic stem cells with a sensory neuron phenotype upon neural induction.

  7. High TLX3/BCL11B (show BCL11B Antibodies) fusion protein expression is associated with T/myeloid acute bilineal leukemia.

  8. HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis.

  9. Authors conclude that RNX, and presumably its expression, are not altered in the index cases of congenital central hypoventilation syndrome.

  10. High incidence of Hox11L2 expression in children with T-ALL

TLX3 Antigen Profile

Protein Summary

RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine-47 replacing cytosine in the highly conserved homeodomain (Dear et al., 1993

Gene names and symbols associated with TLX3

  • T-cell leukemia homeobox 3 (tlx3) antibody
  • T-cell leukemia homeobox 3 (TLX3) antibody
  • T-cell leukemia homeobox 3 (LOC100340221) antibody
  • T cell leukemia, homeobox 3 (Tlx3) antibody
  • T-cell leukemia, homeobox 3 (Tlx3) antibody
  • HOX11L2 antibody
  • RGD1564190 antibody
  • RNX antibody
  • TLX-3 antibody
  • Tlx1l2 antibody
  • TLX3 antibody
  • tlx3-a antibody
  • XHox11L2 antibody

Protein level used designations for TLX3

T-cell leukemia homeobox 3 , homeobox protein 11-like 2 , T-cell leukemia homeobox protein 3 , T-cell leukemia, homeobox 3 , homeo box 11-like 2 , homeobox TLX-3 , homeobox protein Hox-11L2 , respiratory neuron homeobox protein

GENE ID SPECIES
373831 Xenopus laevis
471737 Pan troglodytes
548656 Xenopus (Silurana) tropicalis
618473 Bos taurus
100340221 Oryctolagus cuniculus
27140 Mus musculus
30012 Homo sapiens
489123 Canis lupus familiaris
789584 Bos taurus
395867 Gallus gallus
497881 Rattus norvegicus
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