You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-T-Cell Leukemia/lymphoma 1A (TCL1A) Antibodies

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM. Additionally we are shipping T-Cell Leukemia/lymphoma 1A Proteins (19) and T-Cell Leukemia/lymphoma 1A Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TCL1A 21432 P56280
TCL1A 8115 P56279
TCL1A 690575  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-T-Cell Leukemia/lymphoma 1A Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TCL1A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain WB Suggested Anti-TCL1A  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN238539 (0.1 ug/ml) staining of Jurkat Cell lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated IHC (fro), IHC (p)   1 mL Log in to see 6 to 8 Days
$1,006.50
Details
Human Mouse Un-conjugated FACS, IHC (p), IP, ICS, WB Staining of Daudi cells with 0.25 µg of Purified Mouse IgG2b Iso Cntrl (ABIN287096) (open histogram) or 0.25 µg of Purified anti -human TCL1 (1 -21) (colored histogram) followed by Biotin Anti -Mouse IgG (ABIN286910)and SAv -PE (ABIN286891). Total viable cells were used for analysis. 100 μg Log in to see 5 to 6 Days
$287.67
Details
Human Mouse PE FACS 100 Tests Log in to see 10 to 12 Days
$293.51
Details
Human Mouse Alexa Fluor 647 FACS 100 Tests Log in to see 10 to 12 Days
$320.68
Details

TCL1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
,

, , , , ,
Human , , , ,
, , ,
,
, , , , , , , , , , , , , , , , ,
Rat (Rattus) ,
,

Top referenced anti-T-Cell Leukemia/lymphoma 1A Antibodies

  1. Human Monoclonal TCL1A Primary Antibody for IHC (fro), IHC (p) - ABIN1109210 : Rodig, Vergilio, Shahsafaei, Dorfman: Characteristic expression patterns of TCL1, CD38, and CD44 identify aggressive lymphomas harboring a MYC translocation. in The American journal of surgical pathology 2007 (PubMed)
    Show all 7 references for ABIN1109210

  2. Human Monoclonal TCL1A Primary Antibody for FACS - ABIN2658007 : Laine, Künstle, Obata, Sha, Noguchi: The protooncogene TCL1 is an Akt kinase coactivator. in Molecular cell 2000 (PubMed)
    Show all 7 references for ABIN2658007

  3. Human Monoclonal TCL1A Primary Antibody for FACS - ABIN2663891 : Noguchi, Ropars, Roumestand, Suizu: Proto-oncogene TCL1: more than just a coactivator for Akt. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 (PubMed)
    Show all 7 references for ABIN2663891

  4. Human Polyclonal TCL1A Primary Antibody for WB - ABIN1944776 : Virgilio, Narducci, Isobe, Billips, Cooper, Croce, Russo: Identification of the TCL1 gene involved in T-cell malignancies. in Proceedings of the National Academy of Sciences of the United States of America 1995 (PubMed)
    Show all 4 references for ABIN1944776

  5. Human Monoclonal TCL1A Primary Antibody for FACS, IHC (p) - ABIN281404 : Herling, Patel, Teitell, Konopleva, Ravandi, Kobayashi, Jones: High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia. in Blood 2007 (PubMed)

  6. Mouse (Murine) Polyclonal TCL1A Primary Antibody for ELISA, WB - ABIN190822 : Shen, Ferguson, Renard, Hoyer, Kim, Hao, Alt, Roeder, Morse, Teitell: Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. in Blood 2006 (PubMed)

More Antibodies against T-Cell Leukemia/lymphoma 1A Interaction Partners

Mouse (Murine) T-Cell Leukemia/lymphoma 1A (TCL1A) interaction partners

  1. results indicate that decreased Cav-1 (show CAV1 Antibodies) in Emu-TCL1 mice significantly delays the onset of CLL and decreases leukemic progression by inhibiting MAPK-Erk (show MAPK1 Antibodies) signaling, suggesting a role for Cav-1 (show CAV1 Antibodies) in the proliferation and progression of CLL

  2. This review discusses the main features of the original TCL1 models and the different lines of research successively developed with particular attention to genetically compound mice and the therapeutic applications in drug development.

  3. Tcl1 expression downregulated a distinct group of genes, including Ndp52 (show CALCOCO2 Antibodies), whose expression is very high in blastocysts but reduced in the primitive ectoderm.

  4. Data indicate that APRIL expression accelerates the onset of TCL1-driven leukemia formation mainly through TACI (show TNFRSF13B Antibodies) activation.

  5. These findings demonstrate cooperation of Tcl1 and the NF-kB pathway in the pathogenesis of aggressive chronic lymphocytic leukemia.

  6. An important role of TCL1 in activating the ER stress response in support for malignant progression of chronic lymphocytic leukemia.

  7. TCL1 and/or other genes in the TCL1 pathway are responsible for the initiation of human chronic lymphocytic leukemia.

  8. Akt (show AKT1 Antibodies) kinase activity can be inhibited by a peptide spanning the betaA strand of the proto-oncogene TCL1

  9. Tcl1 is a coactivator of Akt (show AKT1 Antibodies) signaling, in normal T- and B-cell development and function.

  10. Detailed mechanism for TCL1-augmented signaling helps explain the delayed occurrence of mature T cell expansions and leukemias despite tumorigenic TCL1 dysregulation that begins in early thymocytes.

Human T-Cell Leukemia/lymphoma 1A (TCL1A) interaction partners

  1. Our results suggest that intratumoral TCL1A+ B cells are important for controlling cervical cancer development.

  2. Our study suggests that TCL1 expression profile may have a role in the prediction of overall outcome in patient with MCL (show FH Antibodies) and call for prospective studies.

  3. We investigated TCL1 expression at the protein level in the bone marrow of a series of 59 patients with Waldenstrom macroglobulinemia: 76% of patients expressed TCL1, which appeared to be associated with a pejorative prognostic impact.

  4. Suggest miR (show MLXIP Antibodies)-181b as therapeutic target for chronic lymphocytic leukemia in the Emicro-TCL1 mouse model.

  5. High TCL1A expression is associated with chronic lymphocytic leukemia.

  6. Polymorphic genetic variations of cytochrome P450 19A1 (show CYP19A1 Antibodies) and T-cell leukemia 1A genes in the Tamil population

  7. Peptide-based TCL1-interphase mimics were potent in steric AKT (show AKT1 Antibodies) antagonization.

  8. demonstrated that miR (show MLXIP Antibodies)-3676 targets three consecutive 28-bp repeats within 3'UTR (show UTS2R Antibodies) of TCL1 and showed that miR (show MLXIP Antibodies)-3676 is a powerful inhibitor of TCL1

  9. Case Report: T-cell lymphoblastic leukemia/lymphoma with t(7;14)(p15 (show CDKN2B Antibodies);q32) [TCRgamma-TCL1A translocation] confirmed by FISH.

  10. Report frequent TCL1A rearrangements in T-cell prolymphocytic leukemia with cutaneous involvement.

T-Cell Leukemia/lymphoma 1A (TCL1A) Antigen Profile

Protein Summary

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998

Gene names and symbols associated with TCL1A

  • T-cell leukemia/lymphoma 1A (TCL1A) antibody
  • T cell lymphoma breakpoint 1 (Tcl1) antibody
  • T-cell leukemia/lymphoma 1A (Tcl1a) antibody
  • Tcl1 antibody
  • Tcl1a antibody

Protein level used designations for TCL1A

T-cell leukemia/lymphoma 1A , T-cell lymphoma-1 , T-cell leukemia/lymphoma protein 1A , T-cell lymphoma breakpoint 1 , TCL-1 , oncogene TCL-1 , oncogene TCL1 , protein p14 TCL1 , T-cell leukemia/lymphoma protein 1A (P14 TCL1 protein) (TCL1 oncogene) (TCL-1 protein)

GENE ID SPECIES
506540 Bos taurus
612421 Canis lupus familiaris
741380 Pan troglodytes
21432 Mus musculus
8115 Homo sapiens
690575 Rattus norvegicus
Selected quality suppliers for anti-T-Cell Leukemia/lymphoma 1A (TCL1A) Antibodies
Did you look for something else?