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anti-T-Complex Protein 1 (TCP1) Antibodies

TCP1 encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. Additionally we are shipping T-Complex Protein 1 Kits (7) and T-Complex Protein 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TCP1 21454 P11983
TCP1 8626 Q9H3D4
TCP1 246334 Q9JJP6
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Top anti-T-Complex Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat heart labeled with Rabbit Anti P63 protein/P51A Polyclonal Antibody, Unconjugated (ABIN672336) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ChIP, ICC, IF, WB p63 antibody (pAb) tested by ChIP. Chromatin IP was performed on chromatin from HaCaT cells. PCR primers were used to amplify a region of the FXDR gene promoter. Lane 1: negative control IgG. Lane 2: p63 antibody. Lane 3: Input DNA control. p63 antibody (pAb) tested by immunofluorescence. HaCaT cells stained with p63 antibody (pAb) (1:500 dilution). 100 μL Log in to see 1 to 2 Days
$466.67
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with TNF 2500U/ML 30', using p63 (Phospho-Ser455) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using p63 (Phospho-Ser455) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from LOVO cells treated with nocodazole 1ug/ml 18h, A549 cells treated with nocodazole 1ug/ml 18h and HepG2 cells treated with nocodazole 1ug/ml 18h, using p63 (Phospho-Ser395) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from COS7 cells, using p63 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using p63 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using p63, antibody at 1:100 dilution. WB Image p63 antibody [N2C1], Internal detects TP63 protein by Western blot analysis. A. 50 µg rat brain lysate/extract 7.5 % SDS-PAGE p63 antibody [N2C1], Internal , dilution: 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using p63 , antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB 50 μL Log in to see 10 to 12 Days
$135.88
Details
Human Rabbit Un-conjugated FACS 50 μL Log in to see 10 to 12 Days
$135.88
Details
Chicken Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of p63 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of p63 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details

TCP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-T-Complex Protein 1 Antibodies

  1. Human Polyclonal TCP1 Primary Antibody for FACS - ABIN2666196 : Ghioni, Bolognese, Duijf, Van Bokhoven, Mantovani, Guerrini: Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. in Molecular and cellular biology 2002 (PubMed)
    Show all 7 references for ABIN2666196

  2. Human Polyclonal TCP1 Primary Antibody for IHC, WB - ABIN2666194 : Bénard, Douc-Rasy, Ahomadegbe: TP53 family members and human cancers. in Human mutation 2003 (PubMed)
    Show all 6 references for ABIN2666194

  3. Human Polyclonal TCP1 Primary Antibody for ChIP, ICC - ABIN2668832 : Rhie, Hazelett, Coetzee, Yan, Noushmehr, Coetzee: Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells. in BMC genomics 2014 (PubMed)

  4. Human Polyclonal TCP1 Primary Antibody for IF (p), IHC (p) - ABIN672336 : Yang, Xie, Shu, Liu, Chen, Ruan, Qi: An improved method for the isolation and culture of rat epidermal stem cells. in International journal of clinical and experimental pathology 2013 (PubMed)

More Antibodies against T-Complex Protein 1 Interaction Partners

Mouse (Murine) T-Complex Protein 1 (TCP1) interaction partners

  1. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (show P2RX7 Antibodies) (P2X7R (show P2RX7 Antibodies)) and plays a role in lymphoid neoplasm metastasis.

  2. The data presented here reveal an additional level of interplay between CCT (show FLVCR2 Antibodies) and actin mediated via gelsolin (show GSN Antibodies), suggesting that CCT (show FLVCR2 Antibodies) may influence processes depending on gelsolin (show GSN Antibodies) activity, such as cell motility.

  3. Host CCTalpha (show PCYT1A Antibodies) is required for efficient transcription and replication of rabies virus.

  4. Our data provide new evidence indicating the essential role of the chaperonin CCT in the biogenesis of vertebrate photoreceptor sensory cilia

  5. Results suggest that chaperonin containing t-complex protein 1 (CCT) is required for efficient delivery of enzymatically active toxin to the cytosol and are consistent with a direct role for CCT in translocation of LF through the protective antigen pore.

  6. Normal CCT function is ultimately required for the morphogenesis and survival of sensory neurons of the retina.

  7. TRiC (show MARVELD2 Antibodies)-peptide complexes of the heat shock protein 60 (show HSPD1 Antibodies) family are efficient vehicles of cross-presentation in assays in vitro and in mice in vivo; immunization with TRiC (show MARVELD2 Antibodies) purified from a tumor elicits specific protection against a challenge with that tumor.

  8. downregulated expression in T cells following treatment with bis (show BAG3 Antibodies)(tri (show VANGL2 Antibodies)-n-butylin)oxide (TBTO), an immunotoxic organotin

  9. cellular distribution of CCT during spermatogenesis; in the cytoplasm,it associates to the microtubule organizing center and the manchette; in the nucleus, it concentrates at highly condensed chromatin regions

Human T-Complex Protein 1 (TCP1) interaction partners

  1. Suggest p63 (show RPE65 Antibodies) is a reliable marker in non-small cell lung carcinoma and can be used in differential diagnosis.

  2. demonstrated the role of OTX2 (show OTX2 Antibodies) on TAp63 regulation necessary for the correct formation of macular neuroepithelium

  3. a transcript encoding the death receptor DR5 (show TNFRSF10B Antibodies) originates from an ERV9-LTR inserted upstream of the protein coding regions of the TNFRSF10B (show TNFRSF10B Antibodies) gene, and it shows an expression pattern similar to GTAp63

  4. We report a multiplex nonconsanguineous family with TP63 (show TP63 Antibodies) nonsense mutation leading to a premature termination codon (PTC (show F9 Antibodies)) (p.Gln16X), but the same mutation gave rise to marked phenotypic variability

  5. UPII, GATA3, and p40, when used in combination, are highly sensitive in the differential diagnosis of invasive urothelial carcinoma.

  6. T allele reduced the post-transcriptional levels of TP63 (show TP63 Antibodies) mediated by interfering binding efficiency of miR (show MLXIP Antibodies)-140-5p. In addition, overexpression of miR (show MLXIP Antibodies)-140-5p inhibited bladder cancer cell proliferation and attenuated cell migration

  7. p63 (show RPE65 Antibodies) is a sensitive marker in the diagnosis of mucoepidermoid carcinoma

  8. DeltaNp63-CYGB (show CYGB Antibodies) axis is also present in lung and breast cancer cell lines, indicating that CYGB (show CYGB Antibodies)-mediated ROS (show ROS1 Antibodies)-scavenging activity may also have a role in epithelial tumours

  9. human breast tumors data sets the MTSS1 (show MTSS1 Antibodies)/p63 (show RPE65 Antibodies) co-expression is a negative prognostic factor on patient survival, suggesting that the MTSS1 (show MTSS1 Antibodies)/p63 (show RPE65 Antibodies) axis might be functionally important to regulate breast tumor progression

  10. deltaNp63 has an antimetastatic role in the context of p53 (show TP53 Antibodies) deficiency and epidermis

T-Complex Protein 1 (TCP1) Antigen Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with TCP1

  • t-complex protein 1 (Tcp1) antibody
  • tumor protein p63 (TP63) antibody
  • tumor protein p63 (Tp63) antibody
  • AI528772 antibody
  • AIS antibody
  • B(p51A) antibody
  • B(p51B) antibody
  • c-cpn antibody
  • CCT antibody
  • Cct1 antibody
  • Ccta antibody
  • EEC3 antibody
  • Ket antibody
  • LMS antibody
  • NBP antibody
  • OFC8 antibody
  • p40 antibody
  • p51 antibody
  • p53CP antibody
  • p63 antibody
  • p73H antibody
  • P73l antibody
  • RHS antibody
  • SHFM4 antibody
  • Tcp-1 antibody
  • TP53CP antibody
  • TP53L antibody
  • Tp63 antibody
  • Tp73l antibody
  • TRic antibody
  • Trp63 antibody

Protein level used designations for TCP1

CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , transformation-related protein 63 , tumor protein 63 , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa

GENE ID SPECIES
21454 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
Selected quality suppliers for anti-T-Complex Protein 1 (TCP1) Antibodies
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