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T-Complex Protein 1 Proteins (TCP1)

TCP1 encodes a member of the p53 family of transcription factors. Additionally we are shipping T-Complex Protein 1 Antibodies (105) and T-Complex Protein 1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TCP1 21454 P11983
TCP1 8626 Q9H3D4
TCP1 246334 Q9JJP6
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Top T-Complex Protein 1 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
Human Un-conjugated   5 μg Log in to see 6 to 8 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days

TCP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
Human ,
Rat (Rattus)

More Proteins for T-Complex Protein 1 (TCP1) Interaction Partners

Mouse (Murine) T-Complex Protein 1 (TCP1) interaction partners

  1. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (show P2RX7 Proteins) (P2X7R (show P2RX7 Proteins)) and plays a role in lymphoid neoplasm metastasis.

  2. The data presented here reveal an additional level of interplay between CCT (show FLVCR2 Proteins) and actin mediated via gelsolin (show GSN Proteins), suggesting that CCT (show FLVCR2 Proteins) may influence processes depending on gelsolin (show GSN Proteins) activity, such as cell motility.

  3. Host CCTalpha (show PCYT1A Proteins) is required for efficient transcription and replication of rabies virus.

  4. Our data provide new evidence indicating the essential role of the chaperonin CCT in the biogenesis of vertebrate photoreceptor sensory cilia

  5. Results suggest that chaperonin containing t-complex protein 1 (CCT) is required for efficient delivery of enzymatically active toxin to the cytosol and are consistent with a direct role for CCT in translocation of LF through the protective antigen pore.

  6. Normal CCT function is ultimately required for the morphogenesis and survival of sensory neurons of the retina.

  7. TRiC (show MARVELD2 Proteins)-peptide complexes of the heat shock protein 60 (show HSPD1 Proteins) family are efficient vehicles of cross-presentation in assays in vitro and in mice in vivo; immunization with TRiC (show MARVELD2 Proteins) purified from a tumor elicits specific protection against a challenge with that tumor.

  8. downregulated expression in T cells following treatment with bis (show BAG3 Proteins)(tri (show VANGL2 Proteins)-n-butylin)oxide (TBTO), an immunotoxic organotin

  9. cellular distribution of CCT during spermatogenesis; in the cytoplasm,it associates to the microtubule organizing center and the manchette; in the nucleus, it concentrates at highly condensed chromatin regions

Human T-Complex Protein 1 (TCP1) interaction partners

  1. demonstrated the role of OTX2 (show OTX2 Proteins) on TAp63 regulation necessary for the correct formation of macular neuroepithelium

  2. a transcript encoding the death receptor DR5 (show TNFRSF10B Proteins) originates from an ERV9-LTR inserted upstream of the protein coding regions of the TNFRSF10B (show TNFRSF10B Proteins) gene, and it shows an expression pattern similar to GTAp63

  3. We report a multiplex nonconsanguineous family with TP63 (show TP63 Proteins) nonsense mutation leading to a premature termination codon (PTC (show F9 Proteins)) (p.Gln16X), but the same mutation gave rise to marked phenotypic variability

  4. UPII, GATA3, and p40, when used in combination, are highly sensitive in the differential diagnosis of invasive urothelial carcinoma.

  5. T allele reduced the post-transcriptional levels of TP63 (show TP63 Proteins) mediated by interfering binding efficiency of miR (show MLXIP Proteins)-140-5p. In addition, overexpression of miR (show MLXIP Proteins)-140-5p inhibited bladder cancer cell proliferation and attenuated cell migration

  6. p63 (show RPE65 Proteins) is a sensitive marker in the diagnosis of mucoepidermoid carcinoma

  7. DeltaNp63-CYGB (show CYGB Proteins) axis is also present in lung and breast cancer cell lines, indicating that CYGB (show CYGB Proteins)-mediated ROS (show ROS1 Proteins)-scavenging activity may also have a role in epithelial tumours

  8. human breast tumors data sets the MTSS1 (show MTSS1 Proteins)/p63 (show RPE65 Proteins) co-expression is a negative prognostic factor on patient survival, suggesting that the MTSS1 (show MTSS1 Proteins)/p63 (show RPE65 Proteins) axis might be functionally important to regulate breast tumor progression

  9. deltaNp63 has an antimetastatic role in the context of p53 (show TP53 Proteins) deficiency and epidermis

  10. Both TKTL1 and p63 (show RPE65 Proteins) are independent prognostic factors of the poor outcome of gastric cancer patients

T-Complex Protein 1 (TCP1) Protein Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with T-Complex Protein 1 Proteins (TCP1)

  • t-complex protein 1 (Tcp1)
  • tumor protein p63 (TP63)
  • tumor protein p63 (Tp63)
  • AI528772 protein
  • AIS protein
  • B(p51A) protein
  • B(p51B) protein
  • c-cpn protein
  • CCT protein
  • Cct1 protein
  • Ccta protein
  • EEC3 protein
  • Ket protein
  • LMS protein
  • NBP protein
  • OFC8 protein
  • p40 protein
  • p51 protein
  • p53CP protein
  • p63 protein
  • p73H protein
  • P73l protein
  • RHS protein
  • SHFM4 protein
  • Tcp-1 protein
  • TP53CP protein
  • TP53L protein
  • Tp63 protein
  • Tp73l protein
  • TRic protein
  • Trp63 protein

Protein level used designations for T-Complex Protein 1 Proteins (TCP1)

CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , transformation-related protein 63 , tumor protein 63 , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa

21454 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
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