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TAF15 encodes a member of the TET family of RNA-binding proteins. Additionally we are shipping TAF15 Proteins (3) and many more products for this protein.
Showing 10 out of 69 products:
Cow (Bovine) Polyclonal TAF15 Primary Antibody for IHC, WB - ABIN2779283
Lee, Kim, Pelletier, Kim: Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src. in FEBS letters 2004
Show all 3 references for ABIN2779283
Chicken Polyclonal TAF15 Primary Antibody for WB - ABIN2779282
Mitchell: Protonmotive redox mechanism of the cytochrome b-c1 complex in the respiratory chain: protonmotive ubiquinone cycle. in FEBS letters 1975
Show all 3 references for ABIN2779282
Human Polyclonal TAF15 Primary Antibody for IHC, ELISA - ABIN1534044
Morohoshi, Arai, Takahashi, Tanigami, Ohki: Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins. in Genomics 1997
Show all 2 references for ABIN1534044
Cow (Bovine) Polyclonal TAF15 Primary Antibody for WB - ABIN2778852
Kim, Lee, Jun, Kim: The hTAF II 68-TEC fusion protein functions as a strong transcriptional activator. in International journal of cancer. Journal international du cancer 2008
TAF15 is required for a critical alternative splicing event of the zeta-1 subunit of the glutamate N-methyl-D-aspartate receptor (show GRIN3A Antibodies) (Grin1 (show GRIN1 Antibodies)) that controls the activity and trafficking of NR1 (show GRIN1 Antibodies).
RNA binding by TAF-15 is dependent upon structural elements in the RNA rather than sequence.
our data suggest that TAF15 and TLS/FUS (show FUS Antibodies) operate within similar but not identical hnRNP M (show HNRNPM Antibodies)-TET protein complexes to influence the transcriptional or post-transcriptional output of a particular cell type.
Data indicate that distinct differences in proteins becoming Poly(ADP-ribose) PARylated upon various genotoxic insults are observed, exemplified by the PARylation of RNA-processing factors THRAP3 (show THRAP3 Antibodies) and TAF15 under oxidative stress.
TAF15 depletion inhibits growth & increases apoptosis. Its knockdown affects many genes involved in cell cycle & cell death. Among these, targets of microRNAs generated from the onco-miR-17 locus were overrepresented.
Data show that FUS (show FUS Antibodies) and TAF15 locate to cellular stress granules to a larger extend than EWS (show EWSR1 Antibodies). FET-protein stress granule association most likely is a downstream response to cellular stress.
The existence of a functionally discrete subset of U1 snRNP (show LSM2 Antibodies) in association with TAF15 was suggested and provided further support for the involvement of U1 snRNP (show LSM2 Antibodies) components in early steps of coordinated gene expression.
TAF15 plays a role in RNA transport and/or local RNA translation
Missense mutations of TAF-15, an RNA-binding protein, were found in patients with amyotrophic lateral sclerosis, and gene conferred neurodegeneration when expressend in Drosophila.
REsults suggest the possibility that alterations of TAF15 and EWS might also be involved in the pathogenesis of FUS proteinopathies such as ALS and FTLD.
Rare translocation t(12;17)(p13;q12), this translocation has been reported in 25 cases and its putative molecular consequence, the formation of a TAF15-ZNF384 (show ZNF384 Antibodies) fusion gene, in only six cases.
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kDa
, TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA binding protein 56)
, TATA-binding protein-associated factor 2N
, RBP56/CSMF fusion
, TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56)
, TATA box-binding protein-associated factor 2N (RNA-binding protein 56)
, TBP-associated factor 15