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TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa Proteins (TAF15)

TAF15 encodes a member of the TET family of RNA-binding proteins. Additionally we are shipping TAF15 Antibodies (69) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse TAF15 TAF15 70439  
Rat TAF15 TAF15 287571  
TAF15 8148 Q92804
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Top TAF15 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$498.21
Details

TAF15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) Interaction Partners

Mouse (Murine) TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) interaction partners

  1. TAF15 is required for a critical alternative splicing event of the zeta-1 subunit of the glutamate N-methyl-D-aspartate receptor (show GRIN3A Proteins) (Grin1 (show GRIN1 Proteins)) that controls the activity and trafficking of NR1 (show GRIN1 Proteins).

Human TAF15 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 68kDa (TAF15) interaction partners

  1. RNA binding by TAF-15 is dependent upon structural elements in the RNA rather than sequence.

  2. our data suggest that TAF15 and TLS/FUS (show FUS Proteins) operate within similar but not identical hnRNP M (show HNRNPM Proteins)-TET protein complexes to influence the transcriptional or post-transcriptional output of a particular cell type.

  3. Data indicate that distinct differences in proteins becoming Poly(ADP-ribose) PARylated upon various genotoxic insults are observed, exemplified by the PARylation of RNA-processing factors THRAP3 and TAF15 under oxidative stress.

  4. TAF15 depletion inhibits growth & increases apoptosis. Its knockdown affects many genes involved in cell cycle & cell death. Among these, targets of microRNAs generated from the onco-miR-17 locus were overrepresented.

  5. Data show that FUS (show FUS Proteins) and TAF15 locate to cellular stress granules to a larger extend than EWS (show EWSR1 Proteins). FET-protein stress granule association most likely is a downstream response to cellular stress.

  6. The existence of a functionally discrete subset of U1 snRNP (show LSM2 Proteins) in association with TAF15 was suggested and provided further support for the involvement of U1 snRNP (show LSM2 Proteins) components in early steps of coordinated gene expression.

  7. TAF15 plays a role in RNA transport and/or local RNA translation

  8. Missense mutations of TAF-15, an RNA-binding protein, were found in patients with amyotrophic lateral sclerosis, and gene conferred neurodegeneration when expressend in Drosophila.

  9. REsults suggest the possibility that alterations of TAF15 and EWS might also be involved in the pathogenesis of FUS proteinopathies such as ALS and FTLD.

  10. Rare translocation t(12;17)(p13;q12), this translocation has been reported in 25 cases and its putative molecular consequence, the formation of a TAF15-ZNF384 (show ZNF384 Proteins) fusion gene, in only six cases.

TAF15 Protein Profile

Protein Summary

This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with TAF15

  • TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf15)
  • TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa (TAF15)
  • 68kDa protein
  • 2610111C21Rik protein
  • Npl3 protein
  • RBP56 protein
  • TAF2N protein
  • TAFII68 protein

Protein level used designations for TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kDa , TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA binding protein 56) , TATA-binding protein-associated factor 2N , RBP56/CSMF fusion , TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) , TATA box-binding protein-associated factor 2N (RNA-binding protein 56) , TBP-associated factor 15

GENE ID SPECIES
70439 Mus musculus
287571 Rattus norvegicus
8148 Homo sapiens
417522 Gallus gallus
536067 Bos taurus
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